Midsystolic Carotid Pulse Wave Retraction in Subjects with Prolapsed Mitral Valve Leaflets

In recent years, researchers have mainly focused on the humoral and endogenous predictors of atherosclerosis, not paying due attention to anatomical, functional and biomechanical factors. The purpose of the study is an anatomical and functional analysis of the role of extrasystoles as a risk factor for atherosclerosis of the arterial vessels. A total of 270 patients with supraventricular and ventricular extrasystoles were examined. Among the patients there were 162 men and 108 women aged 63.4 ± 6.6 years. The patients underwent sphygmography, electrocardiography, echocardiography and Doppler ultrasound of the arterial main vessels. Anatomical and functional and biomechanical indices of the heart and vessels were determined. The results of the study showed that there are four structural and functional effects of extrasistoly, which play an important role as predictors of atherosclerosis (arterial sprain, mechanical damage to their endothelium, the appearance of additional pulsation waves and the formation of atheroma). The authors believe that the risk factor is not the extrasystole itself, but the pulse wave of the first post-extrasystolic contraction, especially after an early extrasystole, which occurred before the opening of the mitral valve, therefore the treatment tactics and the expediency of its at extrasystoles in many aspects is determined by the degree of hemodynamic disturbances in each specific variant of this rhythm disturbance.

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Effect of Edge-to-Edge-Repair on Annulus Tension of Prolapsed Mitral Valve

ASME 2010 Summer Bioengineering Conference, Parts A and B ◽

10.1115/sbc2010-19571 ◽

2010 ◽

Author(s):

Shamik Bhattacharya ◽

Zhaoming He

Keyword(s):

Mitral Valve ◽

Heart Surgery ◽

Open Heart Surgery ◽

Force Component ◽

Posterior Leaflet ◽

Ring Annuloplasty ◽

Repair Procedure ◽

Prolapsed Mitral Valve ◽

Leaflet Prolapse

The edge-to-edge repair (ETER) technique is a mitral valve (MV) repair procedure. It approximates the leading edges of the mitral leaflets by use of sutures, exhibits promising predictable repair results and offers the advantage of being performed pericutaneously without the need for open heart surgery. The technique is becoming a popular surgical procedure to correct MV prolapse caused by abnormal chordal elongation. MV prolapse leads to mitral regurgitation (MR). Generally the ETER technique is performed as a secondary procedure to ring annuloplasty. Although some groups have performed ETER without the ring annuloplasty, recent studies have shown that ETER technique alone leads to substandard results [1]. It is necessary to define the MV annulus mechanics in ETER condition during valve closure or mid-systole as it directly affects the annulus tension (AT) in the annulus plane. AT in the annulus plane is an important force component which balances the myocardium force and contributes to maintaining the annulus shape and size. This AT change caused by the ETER can lead to annulus dilation, reoccurrence of MR and impact reintervention. The objective of the current study is to understand this AT change in the MV annulus tension during the mid-systole in the ETER condition in order to improve the long term efficacy of the ETER procedure on MV annulus tension, after the technique has been applied with both anterior leaflet prolapse and posterior leaflet prolapse.

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Pulmonary Hypertension Care Centers: Hope for the Future From a Patient's and Caregiver's Perspectives

Advances in Pulmonary Hypertension ◽

10.21693/1933-088x-13.4.172 ◽

2015 ◽

Vol 13 (4) ◽

pp. 172-173

Author(s):

Diane Ramirez ◽

Laura Hoyt D'Anna

Keyword(s):

United States ◽

Pulmonary Hypertension ◽

Mitral Valve ◽

Support Groups ◽

Lung Transplant ◽

Primary Pulmonary Hypertension ◽

The United States ◽

Advocacy Group ◽

Lack Of Information ◽

Prolapsed Mitral Valve

In 1987, after three years of being treated aggressively for asthma and then a prolapsed mitral valve, I was finally diagnosed with primary pulmonary hypertension (PPH). I was told I would be lucky if I lived 2 years without having a heart/double lung transplant and that I didn't have much time to get my affairs in order. There were fewer than 200 patients in the United States at the time. There were no treatment centers, support groups, or even an advocacy group like the Pulmonary Hypertension Association (PHA). I struggled with the loneliness of this diagnosis and the lack of information available.

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