scholarly journals Liver Function Test in Cholestasis

2018 ◽  
Vol 35 (7-8) ◽  
pp. 180-4
Author(s):  
Kompiang Gautama ◽  
Anki Tri Rini ◽  
Sudaryati S.

Cholestasis is impaired bile flow that cause prolonged evacuation of conjugated bilirubin and other substances which are dependent of bile flow for its excretion. The liver function test is useful to determine the severity of disease, to follow up its progress, and to predict the prognosis. This study was performed restropectively from the medical record of cholestatic patients who were admitted to the Department of Child Health, Central Hospital of Denpasar, from January 1992 to December 1993. Among 34 patients with cholestasis, 27 (19 intrahepatic and 8 extrahepatic cholestasis) were included in this study. Although the means of transaminase enzymes (SGOT, SGPT) in intrahepatic cholestasis were higher significantly than those in extrahepatic cholestasis, the increase of these enzymes five times or more than normal was not different significantly. The means of GGT and alkaline phospatase (AP) in extrahepatic groups were higher significantly than those in intrahepatic groups, and the increase of GGT more five times than normal was dilferent significantly as well. The means of total and conjugated bilirubin levels were higher in .extrahepatic group, but were not dilferent significantly.

2021 ◽  
Author(s):  
xiangxi zhou ◽  
fan zhang ◽  
yong Ao ◽  
chun lu ◽  
ting li ◽  
...  

Abstract Objective: To identify the obstacles preventing and controlling hepatitis B and put forward suggestions for its prevention and treatment by describing the discovery process of hepatitis B patients. Methods: We conducted face-to-face interviews with 50 hepatitis B patients in Chongqing, China from July to August 2019 by constructing a thematic analysis framework, which included interviewees’ social demographic characteristics, diagnosis approach, signs and symptoms at the time of discovery, feelings after diagnosis, and doctor’s instructions.Results: Most of the patients were firstly found hepatitis B via physical examination when patients were asymptomatic or had no obvious symptoms. The majority of them were shocked, frightened, and at a loss when they were diagnosed. The patients could remember doctor’s instructions on keeping healthy lifestyle, but they had very little impression about doctors’ reminding about regular liver function test. Failure of regular follow-up to liver function test brought irreversible loss for certain patients.Conclusions: Most of the patients were found hepatitis B passively. The patients need professional mental help after the diagnosis to overcome the negative emotion. The doctors’ instruction should emphasize more on the importance of regular follow-up to liver function test besides health lifestyle.


1966 ◽  
Vol 1 (1) ◽  
pp. 40-41
Author(s):  
S. Yamaoka ◽  
M. Kawamura ◽  
M. Abe ◽  
T. Oshita ◽  
T. Nose

2018 ◽  
Vol 5 (4) ◽  
pp. 1323
Author(s):  
Shreyas Bhalerao Shreyas Bhalerao ◽  
Pooja Batra ◽  
Maneshwar Singh Utaal ◽  
Chirag Sasan

Background:Different factors influencing the post cholecystectomy CBD diameter have been implicated. Ultrasound has emerged as a diagnostic imaging method of choice for liver and extrahepatic biliary system. In order to differentiate the diagnosis of asymptomatic bile duct dilatation, one needs to perform either MRCP or ERCP, which are both expensive and/or invasive test. Therefore, it is necessary to understand the physiological changes in bile duct after cholecystectomy to reduce unnecessary testing for early detection of bile duct lesions.Methods: 100 cases of gall stone disease undergoing cholecystectomy in the department of surgery were studied. Pre operative and Post operative Ultrasound whole abdomen with focus on CBD diameter and Liver function test were done, Post operative data was collected on 10th day and again after 3 months. The data was compiled, compared and analysed.Results:The mean preoperative diameter was 4.12 mm, postoperatively, the mean diameter of the CBD in early follow up period i.e. at 10th day and at 3 months, was found to be 4.75 and 5.14 mm respectively. The difference between mean preoperative and mean postoperative (10th day follow up) diameter was found to be 0.63 mm (p<0.01). The difference between mean preoperative and mean postoperative (3 months follow up) diameter was found to be 1.02 (p<0.01) mm, both statistically significant. Conclusions:Significant compensatory dilatation does occur in common bile duct diameter after cholecystectomy in most of the patients.


2003 ◽  
Vol 124 (4) ◽  
pp. A754-A755
Author(s):  
Elwyn Elias ◽  
Charles Mills ◽  
Marc Halphen ◽  
Norman Barras ◽  
Hans-Juergen Gruss

1928 ◽  
Vol 25 (8) ◽  
pp. 675-677
Author(s):  
A. R. Bernheim

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