scholarly journals Qualitative Interviews on The Diagnosis Process of Hepatitis B Among 50 Patients in Chongqing, China

2021 ◽  
Author(s):  
xiangxi zhou ◽  
fan zhang ◽  
yong Ao ◽  
chun lu ◽  
ting li ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Liver Function ◽  
Liver Function Test ◽  
Healthy Lifestyle ◽  
Negative Emotion ◽  
Qualitative Interviews ◽  
Signs And Symptoms ◽  
Health Lifestyle ◽  
Function Test

Abstract Objective: To identify the obstacles preventing and controlling hepatitis B and put forward suggestions for its prevention and treatment by describing the discovery process of hepatitis B patients. Methods: We conducted face-to-face interviews with 50 hepatitis B patients in Chongqing, China from July to August 2019 by constructing a thematic analysis framework, which included interviewees’ social demographic characteristics, diagnosis approach, signs and symptoms at the time of discovery, feelings after diagnosis, and doctor’s instructions.Results: Most of the patients were firstly found hepatitis B via physical examination when patients were asymptomatic or had no obvious symptoms. The majority of them were shocked, frightened, and at a loss when they were diagnosed. The patients could remember doctor’s instructions on keeping healthy lifestyle, but they had very little impression about doctors’ reminding about regular liver function test. Failure of regular follow-up to liver function test brought irreversible loss for certain patients.Conclusions: Most of the patients were found hepatitis B passively. The patients need professional mental help after the diagnosis to overcome the negative emotion. The doctors’ instruction should emphasize more on the importance of regular follow-up to liver function test besides health lifestyle.

scholarly journals Diagnosis experiences from 50 hepatitis B patients in Chongqing, China: a qualitative study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiangxi Zhou ◽  
Fan Zhang ◽  
Yongping Ao ◽  
Chunli Lu ◽  
Tingting Li ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Liver Function ◽  
Healthy Lifestyle ◽  
Signs And Symptoms ◽  
Liver Function Tests ◽  
Irreversible Damage ◽  
Function Tests ◽  
Professional Mental Health ◽  
The Impact

Abstract Background The aim of this study was to provide recommendations for reducing the impact of hepatitis B infection on patients with chronic hepatitis B by describing their experiences during the diagnosis process. Methods We conducted face-to-face interviews with 50 hepatitis B patients recruited by convenient sampling from an infectious diseases department of a teaching hospital in Chongqing, China from July to August 2019. Thematic analysis framework included interviewees’ social demographic characteristics, diagnosis approach, signs and symptoms before diagnosis, feelings after diagnosis, and doctor’s instructions. Results Most patients first detected hepatitis B through various types of physical examinations when the patients were asymptomatic or had only mild symptoms. Most patients were shocked, scared, or overwhelmed when they were diagnosed with hepatitis B. They were able to remember the doctor’s instructions about maintaining a healthy lifestyle, but not impressed by the doctor’s advice about regular follow-up liver function tests. The lack of regular follow-up has caused irreversible damage to some patients. Conclusions Most patients are passively diagnosed with hepatitis B due to their lack of awareness on active hepatitis B prevention. Patients need professional mental health care to overcome the negative emotions that following the diagnosis. Physicians’ instruction should emphasize the importance of regular follow-up liver function tests in addition to a healthy lifestyle.

scholarly journals Hepatitis B Virus Genotypes in the Kingdom of Bahrain: Prevalence, Gender Distribution and Impact on Hepatic Biomarkers

Medicina ◽  
2019 ◽  
Vol 55 (10) ◽  
pp. 622 ◽  
Author(s):  
Essam M. Janahi ◽  
Zahra Ilyas ◽  
Sara Al-Othman ◽  
Abdulla Darwish ◽  
Sanad J. Sanad ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Liver Function ◽  
Liver Function Test ◽  
Gamma Glutamyl Transferase ◽  
Hbv Genotypes ◽  
B Virus ◽  
Function Test ◽  
Glutamyl Transferase ◽  
Genotype A

Background: Approximately 400 million people are infected with Hepatitis B virus (HBV) around the world, which makes it one of the world’s major infectious diseases. The prevalence of HBV genotypes and predictive factors for risk are poorly known in the Kingdom of Bahrain. Objectives: The aim of the present study was to investigate the prevalence of HBV genotypes, its correlation with demographic factor sand impacts on hepatic biomarkers. Materials and Methods: Venous blood samples were collected from 82 HBV positive patients (48 males, 34 females). The extraction of HBV DNA, PCR amplification, and genotyping were done to classify different genotypes (A, A/D, B, B/D, C, D, D/E, E). HBV genotypes association with gender, nationality, mode of transmission, and liver cirrhosis complication was determined by descriptive statistic and univariate analysis of variance (ANOVA). For liver function test, unpaired t-test and ANOVA were performed. Results: The predominant genotype among patients under study was genotype D (61%), followed by genotype A (10%), and lowest frequency was found for undetermined genotype (1%). In general, there was no significant association between the different genotypes and some demographical factors, serological investigations, and liver function test. The prevalence of HBV genotypes was higher in male patients as compared to female patients and higher in non-Bahraini than in Bahraini. Patients with the dominant genotype D showed higher than the normal maximum range for alanine aminotransferase (ALT) (mean = 45.89) and Gamma-glutamyl transferase (GGT) (mean = 63.36). Conclusions: The most common HBV genotype in Bahrain was genotype D, followed by genotype A. Further studies involving the sources of transmission and impact of hepatic biomarker in Bahrain are required to enhance the control measures of HBV infections.

scholarly journals Liver Function Test on HBsAg Positive Blood Donors

2018 ◽  
Vol 4 ◽  
pp. 9-10 ◽  
Author(s):  
Amrit MS Maharjan ◽  
Bharat Jha ◽  
Anjana Singh
Keyword(s):  
Hepatitis B ◽  
Liver Function ◽  
Liver Function Test ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Albumin Level ◽  
Normal Range ◽  
Serum Samples ◽  
B Virus ◽  
Function Test

Objectives: The study was done to assess liver function test among hepatitis B surface antigen (HBsAg) positive blood donors.Methods: Liver function test (LFT) were studied in 71 HBsAg positive serum samples from healthy blood donors.Results: In the study, 14(19.7Ü) serum samples showed elevated alanine aminotransferase (ALT) level above the normal range (5_35 IU/I) with mean 66.3±27.6; 16(22.5%) showed aspartate aminotransferase (AST) level above the normal range (5-40 IU/I) with mean 87.5±35.7; 4(5.6%) serum samples showed alkaline phosphatase (ALP) level above the normal range (306 IU/I) with mean 376.5±31.5; 49(69%) samples were found to be below the normal albumin level (38-51gm/I) with mean 23.9±5.76.Conclusion: Deviations in the serum enzymes (ALT, AST and ALP) as well as total protein and albumin level showed the silent infection of hepatitis B virus in healthy blood donors.  

scholarly journals Liver Function Test in Cholestasis

2018 ◽  
Vol 35 (7-8) ◽  
pp. 180-4
Author(s):  
Kompiang Gautama ◽  
Anki Tri Rini ◽  
Sudaryati S.
Keyword(s):  
Liver Function ◽  
Liver Function Test ◽  
Bile Flow ◽  
Central Hospital ◽  
Extrahepatic Cholestasis ◽  
Severity Of Disease ◽  
Function Test ◽  
Other Substances ◽  
Conjugated Bilirubin

Cholestasis is impaired bile flow that cause prolonged evacuation of conjugated bilirubin and other substances which are dependent of bile flow for its excretion. The liver function test is useful to determine the severity of disease, to follow up its progress, and to predict the prognosis. This study was performed restropectively from the medical record of cholestatic patients who were admitted to the Department of Child Health, Central Hospital of Denpasar, from January 1992 to December 1993. Among 34 patients with cholestasis, 27 (19 intrahepatic and 8 extrahepatic cholestasis) were included in this study. Although the means of transaminase enzymes (SGOT, SGPT) in intrahepatic cholestasis were higher significantly than those in extrahepatic cholestasis, the increase of these enzymes five times or more than normal was not different significantly. The means of GGT and alkaline phospatase (AP) in extrahepatic groups were higher significantly than those in intrahepatic groups, and the increase of GGT more five times than normal was dilferent significantly as well. The means of total and conjugated bilirubin levels were higher in .extrahepatic group, but were not dilferent significantly.

The follow up study of liver function test after blood transfusion and prognosis of serum hepatitis

1966 ◽  
Vol 1 (1) ◽  
pp. 40-41
Author(s):  
S. Yamaoka ◽  
M. Kawamura ◽  
M. Abe ◽  
T. Oshita ◽  
T. Nose
Keyword(s):  
Blood Transfusion ◽  
Liver Function ◽  
Liver Function Test ◽  
Serum Hepatitis ◽  
Follow Up Study ◽  
Function Test

scholarly journals Evaluation of effect of cholecystectomy on common bile duct diameter using ultrasonography and liver function test: a prospective study

2018 ◽  
Vol 5 (4) ◽  
pp. 1323
Author(s):  
Shreyas Bhalerao Shreyas Bhalerao ◽  
Pooja Batra ◽  
Maneshwar Singh Utaal ◽  
Chirag Sasan
Keyword(s):  
Bile Duct ◽  
Common Bile Duct ◽  
Liver Function ◽  
Liver Function Test ◽  
Imaging Method ◽  
Duct Diameter ◽  
Function Test ◽  
The Difference ◽  
Common Bile Duct Diameter

Background:Different factors influencing the post cholecystectomy CBD diameter have been implicated. Ultrasound has emerged as a diagnostic imaging method of choice for liver and extrahepatic biliary system. In order to differentiate the diagnosis of asymptomatic bile duct dilatation, one needs to perform either MRCP or ERCP, which are both expensive and/or invasive test. Therefore, it is necessary to understand the physiological changes in bile duct after cholecystectomy to reduce unnecessary testing for early detection of bile duct lesions.Methods: 100 cases of gall stone disease undergoing cholecystectomy in the department of surgery were studied. Pre operative and Post operative Ultrasound whole abdomen with focus on CBD diameter and Liver function test were done, Post operative data was collected on 10th day and again after 3 months. The data was compiled, compared and analysed.Results:The mean preoperative diameter was 4.12 mm, postoperatively, the mean diameter of the CBD in early follow up period i.e. at 10th day and at 3 months, was found to be 4.75 and 5.14 mm respectively. The difference between mean preoperative and mean postoperative (10th day follow up) diameter was found to be 0.63 mm (p<0.01). The difference between mean preoperative and mean postoperative (3 months follow up) diameter was found to be 1.02 (p<0.01) mm, both statistically significant. Conclusions:Significant compensatory dilatation does occur in common bile duct diameter after cholecystectomy in most of the patients.

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