scholarly journals TRIPLE NEGATIVE APOCRINE CARCINOMA OF BREAST: A CASE REPORT

2016 ◽  
Vol 5 (68) ◽  
pp. 4937-4938
Author(s):  
Devadhason Darwin Britto ◽  
Arun Prasanth ◽  
Alankrith Ramesh Kashyap ◽  
Floret Soundrapandian ◽  
Vidya Thiagu
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sawsan Ismail ◽  
Haidara Kherbek ◽  
Jana Skef ◽  
Nadim Zahlouk ◽  
Rafik Abdulal ◽  
...  

Abstract Background Apocrine carcinoma is a rare tumor that constitutes < 4% of all breast malignancies, characterized by the proliferation of large atypical cells with strictly defined borders, abundant eosinophilic cytoplasm, large nuclei, and prominent nucleoli in more than 90% of tumor cells. Triple-negative apocrine carcinoma is a rare molecular subtype that constitutes less than 1% of triple-negative breast cancers and is characterized by negative expression of estrogen receptor, progesterone receptor, and human epidermal growth factor receptor, with positive expression of androgen receptor. Case presentation We report a case of a 45-year-old Syrian female who presented to our hospital due to a painless palpable mass in her left breast. Following physical and radiological examinations, an excisional biopsy was performed. Microscopic examination of the specimen followed by immunohistochemical staining revealed the diagnosis of a triple-negative apocrine carcinoma. Conclusion Triple-negative apocrine carcinoma is an extremely rare neoplasm that must be considered in the differential diagnoses of breast lesions through detailed clinical, histological, and immunohistochemical correlations. In our manuscript, we aimed to present the first case report of a Syrian female who was diagnosed with a triple-negative apocrine carcinoma, aiming to highlight the importance of detailed clinical, histological and immunohistochemical correlations with a detailed review of diagnostic criteria, molecular characteristics, and treatment recommendations.


2005 ◽  
Vol 77 (3) ◽  
pp. 285-289 ◽  
Author(s):  
Shinji Shimato ◽  
Toshihiko Wakabayashi ◽  
Masaaki Mizuno ◽  
Norimoto Nakahara ◽  
Hisashi Hatano ◽  
...  

2021 ◽  
Vol 16 (3) ◽  
pp. 606
Author(s):  
Sheena Ali ◽  
Rohit Balasubramanian ◽  
A Manohar ◽  
SangitaS Mehta

2011 ◽  
Vol 45 (3) ◽  
pp. 326
Author(s):  
Jeana Kim ◽  
Tae-Eun Kim ◽  
Ah-Won Lee ◽  
Yeong-Jin Choi ◽  
Kyo-Young Lee ◽  
...  

2019 ◽  
Author(s):  
Yoji Yamagishi ◽  
Takahiro Einama ◽  
Tamio Yamasaki ◽  
Tomomi Koiwai ◽  
Miyuki Hiratsuka ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Jyotsna V. Wader ◽  
Akash Jain ◽  
Suresh J. Bhosale ◽  
Pandurang G. Chougale ◽  
Sujata S. Kumbhar

Apocrine carcinoma is a very rare form of breast malignancy with an incidence of <1% of female invasive breast carcinoma. We report a case of apocrine carcinoma in a 42-year female with marked adenosis showing apocrine metaplasia and discuss the criteria to diagnose apocrine carcinoma with the emerging concept of androgen receptor positivity with its implication on treatment and management of the patient.


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