scholarly journals A CASE OF MIXED CONNECTIVE TISSUE DISORDER WITH INTERSTITIAL LUNG DISEASE: CASE REPORT

2016 ◽  
Vol 5 (33) ◽  
pp. 1860-1862
Author(s):  
Bency Thomas K ◽  
Praveen Radhakrishnan ◽  
Yuvarajan S
Keyword(s):  
Case Report ◽  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Lung Disease ◽  
Connective Tissue Disorder ◽  
Disease Case ◽  
Mixed Connective Tissue Disorder

scholarly journals Undifferentiated connective tissue disease presenting with prevalent interstitial lung disease: Case report and review of literature

2011 ◽  
Vol 6 (1) ◽  
pp. 50 ◽  
Author(s):  
Francesca Lunardi ◽  
Elisabetta Balestro ◽  
Beatrice Nordio ◽  
Franco Cozzi ◽  
Roberta Polverosi ◽  
...  
Keyword(s):  
Case Report ◽  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Lung Disease ◽  
Connective Tissue Disease ◽  
Undifferentiated Connective Tissue Disease ◽  
Review Of Literature ◽  
Disease Case

Rituximab-Induced Interstitial Lung Disease: Case Report and Literature Review

Pharmacology ◽  
2011 ◽  
Vol 87 (5-6) ◽  
pp. 318-320 ◽  
Author(s):  
Aymen Zayen ◽  
Henda Rais ◽  
Hela Rifi ◽  
Mouna Ouarda ◽  
Mehdi Afrit ◽  
...  
Keyword(s):  
Case Report ◽  
Interstitial Lung Disease ◽  
Literature Review ◽  
Lung Disease ◽  
Disease Case

scholarly journals Distal Renal Tubular Acidosis as complication of Mixed Connective Tissue Disorder with autoimmune hypothyroidism- a case report

2016 ◽  
Vol 27 (1) ◽  
pp. 37-39
Author(s):  
Md Daharul Islam ◽  
SM Tajdit Rahman ◽  
Khaleda Akter ◽  
Md Azizul Hoque
Keyword(s):  
Case Report ◽  
Connective Tissue ◽  
Renal Tubular Acidosis ◽  
Connective Tissue Disorder ◽  
Distal Renal Tubular Acidosis ◽  
Undifferentiated Connective Tissue Disease ◽  
Acid Transport ◽  
Autoimmune Hypothyroidism ◽  
Renal Tubular ◽  
Mixed Connective Tissue Disorder

Renal tubular acidosis (RTA) is a constellation of syndromes arising from different derangements of tubular acid transport. Multiple associations have been established with renal tubular acidosis. We report a case of distal renal tubular acidosis which may be associated with undifferentiated connective tissue disease in which patient is also having autoimmune hypothyroidism along with that is not very common.Bangladesh J Medicine Jan 2016; 27(1) : 37-39

scholarly journals Mycobacterium intracellulare Infection Mimicking Progression of Scleroderma

2017 ◽  
Vol 2017 ◽  
pp. 1-3
Author(s):  
Simon Krabbe ◽  
Merete Engelhart ◽  
Sören Thybo ◽  
Søren Jacobsen
Keyword(s):  
Case Report ◽  
Listeria Monocytogenes ◽  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Connective Tissue Disorder ◽  
High Dose ◽  
Esophageal Dysmotility ◽  
Mycobacterium Intracellulare ◽  
The Right ◽  
Inflammatory Changes

This case report describes a patient with scleroderma who developed Mycobacterium intracellulare infection, which for more than a year mimicked worsening of her connective tissue disorder. The patient was diagnosed with scleroderma based on puffy fingers that developed into sclerodactyly, abnormal nail fold capillaries, interstitial lung disease, Raynaud’s phenomenon, esophageal dysmotility, and positivity for rheumatoid factor and anti-SSA antibodies. She developed massive inflammatory changes of the cutis, the subcutis, and the muscle fasciae of the right leg, that after several failed attempts of immunosuppressive treatments were found to be caused by Mycobacterium intracellulare. While she was receiving high-dose prednisolone, as worsening of her connective tissue disease was suspected to be the cause of the inflammatory changes, she had Listeria monocytogenes meningitis and was hospitalized for several weeks, but she recovered from this without sequelae. After Mycobacterium intracellulare infection was diagnosed, she was treated with clarithromycin and rifampicin. Her skin manifestations, arthralgias, and fatigue improved considerably, and the wounds of the right leg healed, unfortunately with significant scarring. Immunodeficiency testing was unremarkable. In summary, an infection with Mycobacterium intracellulare was mistaken for an unusually severe progression of scleroderma.

The Pulmonary Histopathology of Anti-KS Transfer RNA Synthetase Syndrome

2015 ◽  
Vol 139 (1) ◽  
pp. 122-125 ◽  
Author(s):  
Frank Schneider ◽  
Rohit Aggarwal ◽  
David Bi ◽  
Kevin Gibson ◽  
Chester Oddis ◽  
...  
Keyword(s):  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Lung Disease ◽  
Interstitial Pneumonia ◽  
Usual Interstitial Pneumonia ◽  
Connective Tissue Disorder ◽  
Transfer Rna ◽  
Organizing Pneumonia ◽  
Antisynthetase Syndrome ◽  
Pulmonary Manifestations

Context The clinical spectrum of the antisynthetase syndromes (AS) has been poorly defined, although some frequently present with pulmonary manifestations. The anti-KS anti–asparaginyl-transfer RNA synthetase syndrome is one in which pulmonary interstitial lung disease is almost always present and yet the histopathologic spectrum is not well described. Objective To define the morphologic manifestations of pulmonary disease in those patients with anti-KS antiasparaginyl syndrome. Design We reviewed the connective tissue disorder registry of the University of Pittsburgh and identified those patients with anti-KS autoantibodies who presented with interstitial lung disease and had surgical lung biopsies. Results The 5 patients with anti-KS antisynthetase syndrome were usually women presenting with dyspnea and without myositis, but with mechanic's hands (60%) and Raynaud phenomenon (40%). They most often presented with a usual interstitial pneumonia pattern of fibrosis (80%), with the final patient displaying organizing pneumonia. Conclusions Pulmonary interstitial lung disease is a common presentation in patients with the anti-KS–antisynthetase syndrome, who are often women with rather subtle or subclinical connective tissue disease, whereas the literature emphasizes the nonspecific interstitial pneumonia pattern often diagnosed clinically. Usual interstitial pneumonia and organizing pneumonia patterns of interstitial injury need to be added to this clinical differential diagnosis.

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