Concurrent Colonic Infection with Strongyloides stercoralis, Cytomegalovirus and Clostridium difficile in an Immunocompromised Host

2012 ◽  
Vol 107 ◽  
pp. S480
Author(s):  
Melissa Reynon ◽  
Nakechand Pooran ◽  
Saroja Rampertab
2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Kartik Natrajan ◽  
Mahenderkumar Medisetty ◽  
Raviraj Gawali ◽  
Ajit Tambolkar ◽  
Divya Patel ◽  
...  

Parasitic infections such as Strongyloides stercoralis and HIV have been reported to coexist, particularly in resource-limited settings such as India. In an immunocompromised host, S. stercoralis can progress to strongyloidiasis hyperinfection syndrome (SHS). However, SHS is not common in patients with advanced HIV disease. Immune reconstitution inflammatory syndrome (IRIS) developing after initiation of antiretroviral therapy (ART) can target multiple pathogens including S. stercoralis. The authors present here a 46-year-old HIV-infected female who was recently diagnosed with HIV-1 infection, started ART, and developed SHS. Her upper GI endoscopy revealed severe gastroduodenitis, and X-ray chest showed extensive bilateral pneumonitis. We could identify S. stercoralis in induced sputum and duodenal biopsy. We could also identify gut inflammation to restrict invading parasites. After receiving antihelminthic therapy, she showed improvement, a course of events that fit the diagnosis of unmasking S. stercoralis IRIS.


Cureus ◽  
2022 ◽  
Author(s):  
Neha Sharma ◽  
Kaveh Zivari ◽  
Daria Yunina ◽  
Matthew Grunwald ◽  
Omar Azar ◽  
...  

2019 ◽  
Vol 6 (7) ◽  
pp. e00135
Author(s):  
Brooks R. Crowe ◽  
Sean M. Duenas ◽  
Antonio Serrano ◽  
Joseph Kingsbery ◽  
Renee Williams

2009 ◽  
Vol 104 ◽  
pp. S267
Author(s):  
Shyam Dang ◽  
Muhannad Heif ◽  
Madan Dang ◽  
Saumya Kumar ◽  
Muslim Atiq ◽  
...  

Anaerobe ◽  
2016 ◽  
Vol 42 ◽  
pp. 31-32 ◽  
Author(s):  
Xuewu Zhang ◽  
Yunbo Chen ◽  
Silan Gu ◽  
Beiwen Zheng ◽  
Tao Lv ◽  
...  

2021 ◽  
Vol 2 (1) ◽  
pp. 47-49
Author(s):  
Mohammad Shohidul Islam

Strongyloidiasis is a chronic self-limited parasitic infection associated with mostly nonspecific sign symptoms. But in immunocompromised patient’s morbidity and mortality is high due to hyperinfection syndrome and disseminated disease. So early diagnosis is very important. Here we report a case of hyperinfection with Strongyloides stercoralis in an elderly immunocompromised patient diagnosed by endoscopic biopsy who was treated successfully later on. Keywords: Strongyloidiasis; parasitic infection; Immunocompromised host, Hyperinfection Disseminated disease


2015 ◽  
Vol 18 (4) ◽  
pp. 160-163
Author(s):  
Ramona Stefania Popescu ◽  
◽  
Adina Ilie ◽  
Rodica Bacruban ◽  
Catalin Apostolescu ◽  
...  

The risk of developing secondary infections in immunocompromised patients due to hematological malignancies and the treatments for such conditions is very well known. Fever can be the only manifestation of a serious infection among this category of patients. The degree and duration of neutropenia is directly related to the risk of multiple infectious complications. When we are dealing with severely impaired host defenses virtually any microorganism can become invasive, bacteria (gram-positive pathogens, but gram-negative as well), being the greatest immediate threat. Multiple pathogens isolated from an immunocompromised host can represent a major challenge for the clinician, especially when we have to face multidrug resistant (MDR) microorganisms, also called “superbugs”. Besides, when we confront such a patient with many comorbidities and a high risk for MDR pathogens infection, we also confront with a lot of limitations in terms of treatment options. We present a complicated case of glycopeptide-resistant Enterococcus faecium sepsis secondary to Clostridium difficile colitis in a 63 years old female patient with B-cell non-Hodgkin Lymphoma (NHL) during the R-CHOP therapy.


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