scholarly journals Clinical characteristics of peripheral type of diabetic retinopathy diagnosed with ultra-wide field fluorescein angiography

2014 ◽  
Vol 7 (1) ◽  
pp. 38a-38a
Author(s):  
Shuichiro Hirahara ◽  
Taneto Tomiyasu ◽  
Miho Nozaki ◽  
Munenori Yoshida ◽  
Yuichiro Ogura
2017 ◽  
Vol Volume 11 ◽  
pp. 803-807 ◽  
Author(s):  
Alessandro Rabiolo ◽  
Mariacristina Parravano ◽  
Lea Querques ◽  
Maria Vittoria Cicinelli ◽  
Adriano Carnevali ◽  
...  

2021 ◽  
pp. bjophthalmol-2020-317488
Author(s):  
Wenying Fan ◽  
Akihito Uji ◽  
Muneeswar Nittala ◽  
Charles Clifton Wykoff ◽  
David Brown ◽  
...  

AimsTo quantify retinal vascular bed area (RVBA) in square millimetres on stereographically projected ultra-wide field (UWF) fluorescein angiography (FA) in eyes with diabetic retinopathy (DR).MethodsA prospective, observational study. Baseline Optos 200Tx UWF FA images of 80 eyes with DR from the DAVE (NCT01552408) and RECOVERY (NCT02863354) studies were stereographically projected at the Doheny Image Reading Center to adjust for peripheral distortion. The early-phase FA frame was used to extract the retinal vasculature as a mask for calculating RVBA. The pixels of the retinal vasculature were automatically computed in square millimetres using manufacturer-provided software.ResultsEighteen of 80 diabetic eyes were excluded because image quality and contrast were insufficient for automatic extraction of the retinal vasculature from the background fluorescence. The remaining 62 eyes were included in the final analysis. In comparison with age-matched and sex-matched normal controls, eyes with DR had a higher global RVBA for the entire retina (p<0.001), and RVBA correlated with DR severity (p<0.001), with a higher RVBA in eyes with proliferative DR (66.1±16.2 mm2) than in those with non-proliferative DR (56.2±16.6 mm2) or in normal controls (37.2±9.9 mm2). This tendency was also present in the posterior retina and mid-periphery but absent in the far-periphery. RVBA did not correlate with retinal ischaemia (p>0.05).ConclusionsEyes with DR harboured a larger global RVBA for the entire retina than normal controls, and RVBA appeared to indicate DR severity. However, this biomarker was not observed to be a good indicator of retinal ischaemia.


2016 ◽  
Vol 57 (13) ◽  
pp. 5278 ◽  
Author(s):  
Abhilash Guduru ◽  
Teresa G. Martz ◽  
Alexa Waters ◽  
Abhijit V. Kshirsagar ◽  
Seema Garg

Retina ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Wenying Fan ◽  
Muneeswar Gupta Nittala ◽  
Charles c Wykoff ◽  
David M. Brown ◽  
Akihito Uji ◽  
...  

2020 ◽  
Author(s):  
Shintaro Horie ◽  
Nobuyuki Kukimoto ◽  
Koju Kamoi ◽  
Tae Igarashi-Yokoi ◽  
Takeshi Yoshida ◽  
...  

Abstract Diabetic retinopathy (DR) is one of the leading causes of blindness worldwide. The retinal ischemic changes in DR need to be detected and treated appropriately to prevent further progression. At present, fluorescein angiography (FA) is the most commonly used method to detect the ischemic areas. We present our results that showed a practical method of detecting retinal ischemic area covering mid-peripheral retina by multicolor widefield scanning laser ophthalmoscopy (SLO) without fluorescein. Ninety patients with and 50 patients without diabetes mellitus were studied retrospectively. All had undergone multicolor widefield SLO imaging. Hyporeflective areas in blue image of SLO were found in the incidence of 76.6% in eyes with proliferative DR eyes. In a comparison of the hyporeflective areas of the blue SLO images to the non-perfused areas in the FA images, the appearance and the correspondence in the locations of these findings in the two types of images were found, and the incidence were highly concordant with Cohen kappa value of 0.785. The high concordance between the hyporeflective areas in the wide-field blue SLO images and the NPAs in the FA images indicates that this method can be clinically useful to identify ischemic retinal areas in DR.


2012 ◽  
Vol 27 (5-6) ◽  
pp. 221-227 ◽  
Author(s):  
Ahmed Z. Soliman ◽  
Paolo S. Silva ◽  
Lloyd Paul Aiello ◽  
Jennifer K. Sun

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