scholarly journals Measurement of the energy spectrum of secondary neutrons in a proton therapy environment

2017 ◽  
Vol 3 (2) ◽  
pp. 83-86
Author(s):  
Martin Dommert ◽  
Marcel Reginatto ◽  
Miroslav Zboril ◽  
Fine Fiedler ◽  
Stephan Helmbrecht ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Energy Spectrum ◽  
Monte Carlo Simulations ◽  
Proton Beam ◽  
Proton Therapy ◽  
Secondary Neutron ◽  
Incoming Proton ◽  
Secondary Neutrons ◽  
Proton Therapy Facility

AbstractMeasurement of the energy spectrum of secondary neutrons were carried out at the OncoRay Proton Therapy facility in Dresden, following an approach originating in neutron metrology which is well suited for both the characterization of secondary neutron fields at proton therapy facilities and the validation of Monte Carlo simulations. For the experiment, a brass target was placed in the proton beam and Bonner spheres measurements were made at a distance of 2 m from the target and at different angles, 15° to 120°, with respect to the incoming proton beam. The measured spectra were compared to Monte Carlo simulations.

Neutron H*(10) inside a proton therapy facility: comparison between Monte Carlo simulations and WENDI-2 measurements

2013 ◽  
Vol 161 (1-4) ◽  
pp. 417-421 ◽  
Author(s):  
V. De Smet ◽  
F. Stichelbaut ◽  
T. Vanaudenhove ◽  
G. Mathot ◽  
G. De Lentdecker ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Proton Therapy ◽  
Proton Therapy Facility

Assessment of secondary neutrons in particle therapy by Monte Carlo simulations

2021 ◽  
Author(s):  
José Vedelago ◽  
Federico A Geser ◽  
Iván D Muñoz ◽  
Alberto Stabilini ◽  
Eduardo G Yukihara ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Angular Distribution ◽  
Monte Carlo Simulations ◽  
Radiation Transport ◽  
Heavy Ion ◽  
High Energy ◽  
Particle Therapy ◽  
Carbon Ions ◽  
Secondary Neutron ◽  
Secondary Neutrons

Abstract Objective: The purpose of this study is to estimate the energy and angular distribution of secondary neutrons inside a phantom in hadron therapy, which will support decisions on detector choice and experimental setup design for in-phantom secondary neutron measurements. Approach: Dedicated Monte Carlo simulations were implemented, considering clinically relevant energies of protons, helium and carbon ions. Since scored quantities can vary from different radiation transport models, the codes FLUKA, TOPAS and MCNP were used. The geometry of an active scanning beam delivery system for heavy ion treatment was implemented, and simulations of pristine and spread-out Bragg peaks were carried out. Previous studies, focused on specific ion types or single energies, are qualitatively in agreement with the obtained results. Main results: The secondary neutrons energy distributions present a continuous spectrum with two peaks, one centred on the thermal/epithermal region, and one on the high-energy region, with the most probable energy ranging from 19 MeV up to 240 MeV, depending on the ion type and its initial energy. The simulations show that the secondary neutron energies may exceed 400 MeV and, therefore, suitable neutron detectors for this energy range shall be needed. Additionally, the angular distribution of the low energy neutrons is quite isotropic, whereas the fast/relativistic neutrons are mainly scattered in the down-stream direction. Significance: It would be possible to minimize the influence of the heavy ions when measuring the neutron-generated recoil protons by selecting appropriate measurement positions within the phantom. Although there are discrepancies among the three Monte Carlo codes, the results agree qualitatively and in order of magnitude, being sufficient to support further investigations with the ultimate goal of mapping the secondary neutron doses both in- and out-of-field in hadrontherapy. The obtained secondary neutron spectra are available as supplementary material.

The radiation fields around a proton therapy facility: A comparison of Monte Carlo simulations

2014 ◽  
Vol 95 ◽  
pp. 236-239 ◽  
Author(s):  
G. Ottaviano ◽  
L. Picardi ◽  
M. Pillon ◽  
C. Ronsivalle ◽  
S. Sandri
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Proton Therapy ◽  
Radiation Fields ◽  
Proton Therapy Facility

scholarly journals A Monte Carlo Determination of Dose and Range Uncertainties for Preclinical Studies with a Proton Beam

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1889
Author(s):  
Arthur Bongrand ◽  
Charbel Koumeir ◽  
Daphnée Villoing ◽  
Arnaud Guertin ◽  
Ferid Haddad ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Proton Beam ◽  
Dose Response ◽  
Small Animal ◽  
Absorbed Dose ◽  
Normal Tissue Damage ◽  
Dose Homogeneity ◽  
And Control ◽  
The Impact

Proton therapy (PRT) is an irradiation technique that aims at limiting normal tissue damage while maintaining the tumor response. To study its specificities, the ARRONAX cyclotron is currently developing a preclinical structure compatible with biological experiments. A prerequisite is to identify and control uncertainties on the ARRONAX beamline, which can lead to significant biases in the observed biological results and dose–response relationships, as for any facility. This paper summarizes and quantifies the impact of uncertainty on proton range, absorbed dose, and dose homogeneity in a preclinical context of cell or small animal irradiation on the Bragg curve, using Monte Carlo simulations. All possible sources of uncertainty were investigated and discussed independently. Those with a significant impact were identified, and protocols were established to reduce their consequences. Overall, the uncertainties evaluated were similar to those from clinical practice and are considered compatible with the performance of radiobiological experiments, as well as the study of dose–response relationships on this proton beam. Another conclusion of this study is that Monte Carlo simulations can be used to help build preclinical lines in other setups.

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