Synthesis and characterization of temperature/pH-sensitive hydroxypropylcellulose/ sodium alginate hydrogel

e-Polymers ◽  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Hui Li ◽  
Guo-li Gong
Keyword(s):  
Sodium Alginate ◽  
Ph Value ◽  
Ph Sensitive ◽  
Swelling Ratio ◽  
Ph Responsive ◽  
Alginate Hydrogel ◽  
Sensitive Material ◽  
Maximum Value ◽  
Responsive Hydrogels

AbstractA series of temperature and pH responsive hydrogels were synthesized by using hydroxypropylcellulose (HPC) as temperature natural sensitive material, sodium alginate (SA) as pH sensitive material. The effect of SA to LCST has been studied and the mechanism of the influence has been presented. In addition, the swelling ratio and controlling factor of swelling process were all researched in this paper. The main results obtained are as follows: the LCST decreased gradually as SA was added into HPC; the HPC/SA hydrogel responded to both temperature and pH value of the medium; the swelling ratio reached maximum value at pH value of 6.

Swelling Characterization of Double Sensitive Hydroxypropylcellulose / Sodium Alginate Hydrogel

2011 ◽  
Vol 221 ◽  
pp. 184-188
Author(s):  
Guo Li Gong ◽  
Hui Li ◽  
Zhen Hua Guo
Keyword(s):  
Sodium Alginate ◽  
Temperature Sensitivity ◽  
Ph Value ◽  
Natural Material ◽  
Swelling Ratio ◽  
Ph Responsive ◽  
Alginate Hydrogel ◽  
Maximum Value ◽  
Responsive Hydrogels

A series of temperature and pH responsive hydrogels was synthesized by using hydroxypropylcellulose (HPC) as temperature sensitivity material and the natural material, sodium alginate (SA) as pH sensitivity material. The effect of SA to LCST has been studied and the mechanism of the influence has been presented. In addition, the swelling ratio and controlling factor of swelling process were all researched in this paper. The main results obtained are as follows: the LCST decreased gradually as added SA into HPC; the HPC/SA hydrogel responded both temperature and pH value of the medium; the swelling ratio reached maximum value as pH value of 6.

Fabrication and characterization of biocompatible pH responsive halloysite nanotubes grafted with sodium alginate for sustained release of phenytoin sodium

2019 ◽  
Vol 43 (26) ◽  
pp. 10523-10530 ◽  
Author(s):  
Leila Zeraatpishe ◽  
Alireza Mohebali ◽  
Majid Abdouss
Keyword(s):  
Controlled Release ◽  
Sustained Release ◽  
Sodium Alginate ◽  
Halloysite Nanotubes ◽  
Ph Sensitive ◽  
New Method ◽  
Ph Responsive ◽  
Phenytoin Sodium ◽  
Fabrication And Characterization

Schematic design of a new method for fabrication of biocompatible pH sensitive halloysite nanocomposites for controlled release of phenytoin sodium.

Synthesis and characterization of pH- and salt-responsive hydrogels based on etherificated sodium alginate

2010 ◽  
Vol 115 (6) ◽  
pp. 3161-3167 ◽  
Author(s):  
Hailin Lin ◽  
Jinjin Zhou ◽  
Cui Yingde ◽  
Sundaram Gunasekaran
Keyword(s):  
Sodium Alginate ◽  
Synthesis And Characterization ◽  
Responsive Hydrogels

Synthesis and characterization of pH-responsive hydrogels based on chemically modified Arabic gum polysaccharide

Polymer ◽  
2006 ◽  
Vol 47 (6) ◽  
pp. 2023-2029 ◽  
Author(s):  
Adriano V. Reis ◽  
Marcos R. Guilherme ◽  
Osvaldo A. Cavalcanti ◽  
Adley F. Rubira ◽  
Edvani C. Muniz
Keyword(s):  
Synthesis And Characterization ◽  
Ph Responsive ◽  
Arabic Gum ◽  
Chemically Modified ◽  
Responsive Hydrogels

pH-Responsive prodrug nanoparticles based on a sodium alginate derivative for selective co-release of doxorubicin and curcumin into tumor cells

Nanoscale ◽  
2017 ◽  
Vol 9 (34) ◽  
pp. 12533-12542 ◽  
Author(s):  
Cheng Gao ◽  
Fan Tang ◽  
Guiyi Gong ◽  
Jianxiang Zhang ◽  
Maggie P. M. Hoi ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Tumor Cells ◽  
Sodium Alginate ◽  
Safety Profile ◽  
Ph Sensitive ◽  
Efficacy And Safety ◽  
Ph Responsive

A pH-sensitive prodrug nanoparticle demonstrated the selective co-delivery of doxorubicin and curcumin into cancer cells with much improved efficacy and safety profile.

Synthesis and Characterization of a Novel Starch-Based pH-Sensitive Hydrogel

2013 ◽  
Vol 303-306 ◽  
pp. 2602-2605 ◽  
Author(s):  
Jie Du ◽  
Tian Qin Zhao ◽  
Yi Liu ◽  
Jing Jie
Keyword(s):  
Ph Sensitive ◽  
Butyl Methacrylate ◽  
Porous Structures ◽  
Stimuli Responsive ◽  
Ft Ir ◽  
Responsive Hydrogels ◽  
Formed Structure ◽  
Novel Starch ◽  
Ph Sensitive Hydrogel

Stimuli-responsive hydrogels are extensively investigated to implement new biomedical and pharmaceutical approaches. In this work, novel pH-sensitive hydrogel, with potassium persulfate as the initiator, acrylic acid and butyl methacrylate as graft monomer, were synthesized by microwave irradiation. FT-IR measurements testified the hydrogels formed structure. The SEM micrographs revealed that the porous structures of hydrogels changed with the increasing AA content. The experimental results demonstrated that the gels do not swell greatly at low pH media whereas they swelled sufficiently at high pH media, exhibiting smart pH sensitivity.

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