Thymidylate synthase inhibitors for non-small cell lung cancer

Expert Opinion on Investigational Drugs ◽

10.1517/13543784.2011.617742 ◽

2011 ◽

Vol 20 (10) ◽

pp. 1343-1356 ◽

Author(s):

Elena Galvani ◽

Godefridus J Peters ◽

Elisa Giovannetti

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Small Cell Lung ◽

Thymidylate Synthase Inhibitors

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Efficacy of Pemetrexed in Relapsed Non-Small Cell Lung Cancer and Thymidylate Synthase Expression

Tuberculosis and Respiratory Diseases ◽

10.4046/trd.2009.67.3.191 ◽

2009 ◽

Vol 67 (3) ◽

pp. 191 ◽

Author(s):

Choel-Kyu Park ◽

Kyu-Sik Kim ◽

In-Jae Oh ◽

Manaljav Tseden-Ish ◽

Yoo-Duk Choi ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Small Cell Lung

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The Pemetrexed-Containing Treatments in the Non-small Cell Lung Cancer, Is -/Low Thymidylate Synthase Expression Better than +/High Thymidylate Synthase Expression? A Meta-analysis

CHEST Journal ◽

10.1378/chest.1832401 ◽

2014 ◽

Vol 145 (3) ◽

pp. 349A

Author(s):

Lei Wang ◽

Rui Wang ◽

Yunjian Pan ◽

Yihua Sun ◽

Jie Zhang ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Meta Analysis ◽

Small Cell Lung ◽

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Pemetrexed/Carboplatin/Bevacizumab followed by Maintenance Pemetrexed/Bevacizumab in Hispanic Patients with Non-Squamous Non-Small Cell Lung Cancer: Outcomes according to Thymidylate Synthase Expression

PLoS ONE ◽

10.1371/journal.pone.0154293 ◽

2016 ◽

Vol 11 (5) ◽

pp. e0154293 ◽

Author(s):

Andrés Felipe Cardona ◽

Leonardo Rojas ◽

Beatriz Wills ◽

Oscar Arrieta ◽

Hernán Carranza ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Cancer Outcomes ◽

Small Cell Lung ◽

Hispanic Patients

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Prognostic and predictive significance of thymidylate synthase protein expression in non-small cell lung cancer: A systematic review and meta-analysis

Cancer Biomarkers ◽

10.3233/cbm-140432 ◽

2015 ◽

Vol 15 (1) ◽

pp. 65-78 ◽

Author(s):

Qingyun Liu ◽

Zubin Yu ◽

Ying Xiang ◽

Na Wu ◽

Long Wu ◽

...

Keyword(s):

Lung Cancer ◽

Systematic Review ◽

Protein Expression ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Meta Analysis ◽

Small Cell Lung

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The deubiquitinating enzyme UCHL1 promotes resistance to pemetrexed in non-small cell lung cancer by upregulating thymidylate synthase

Theranostics ◽

10.7150/thno.42096 ◽

2020 ◽

Vol 10 (13) ◽

pp. 6048-6060

Author(s):

Xinyuan Ding ◽

Yuting Gu ◽

Min Jin ◽

Xin Guo ◽

Sudong Xue ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Deubiquitinating Enzyme ◽

Small Cell Lung

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Abstract 2927: Rapamycin decreases expression of thymidylate synthase and enhances the response to pemetrexed in preclinical studies and a Phase I/II clinical study of subjects with non-small cell lung cancer

10.1158/1538-7445.am2014-2927 ◽

2014 ◽

Author(s):

Shigeru Kawabata ◽

Chun-Te Chiang ◽

Regan M. Memmott ◽

Takefumi Komiya ◽

Joell J. Gills ◽

...

Keyword(s):

Lung Cancer ◽

Clinical Study ◽

Phase I ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Preclinical Studies ◽

Small Cell Lung

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E2F1 Overexpression Correlates with Thymidylate Synthase and Survivin Gene Expressions and Tumor Proliferation in Non–Small-Cell Lung Cancer

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-1539 ◽

2007 ◽

Vol 13 (23) ◽

pp. 6938-6946 ◽

Author(s):

Cheng-long Huang ◽

Dage Liu ◽

Jun Nakano ◽

Hiroyasu Yokomise ◽

Masaki Ueno ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Tumor Proliferation ◽

Small Cell Lung ◽

Gene Expressions ◽

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ERCC1, BRCA1, thymidylate synthase (TS), class III beta tubulin (bTubIII), p53R2, RRM2 immunohistochemical expression in stage I-III non-small cell lung cancer (NSCLC): A tissue microarray (TMA) study.

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.e21094 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. e21094-e21094

Author(s):

F. Grossi ◽

D. F. Merlo ◽

S. Salvi ◽

D. Bordo ◽

C. Genova ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Tissue Microarray ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Stage I ◽

Class Iii ◽

Immunohistochemical Expression ◽

Small Cell Lung

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Intratumoral expression of thymidylate synthase and dihydropyrimidine dehydrogenase in non-small cell lung cancer patients treated with 5-FU-based chemotherapy.

International Journal of Oncology ◽

10.3892/ijo.17.1.47 ◽

2000 ◽

Author(s):

C L Huang ◽

H Yokomise ◽

S Kobayashi ◽

M Fukushima ◽

S Hitomi ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Dihydropyrimidine Dehydrogenase ◽

Small Cell Lung ◽

Lung Cancer Patients

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Efficacy of platinum-based chemotherapy in EGFR WT nonsquamous advanced non-small cell lung cancer (NSCLC) patients: association with KRAS mutation and thymidylate synthase (TS) levels

Annals of Oncology ◽

10.1093/annonc/mdx426.013 ◽

2017 ◽

Vol 28 ◽

pp. vi58-vi59

Author(s):

B. Ricciuti ◽

R. Chiari ◽

F.R. Tofanetti ◽

A. De Giglio ◽

R. Porreca ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Thymidylate Synthase ◽

Kras Mutation ◽

Small Cell Lung ◽

Platinum Based Chemotherapy ◽

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