Statin use and the risk of esophageal cancer: a population-based case-control study

2013 ◽  
Vol 12 (3) ◽  
pp. 293-298 ◽  
Author(s):  
Te-Fu Chan ◽  
Hui-Fen Chiu ◽  
Chen-Hsuan Wu ◽  
Chih-Lung Lin ◽  
Chun-Yuh Yang
2015 ◽  
Vol 95 (2) ◽  
pp. 227-232 ◽  
Author(s):  
C.Y. Huang ◽  
S.D. Chung ◽  
L.T. Kao ◽  
H.C. Lin ◽  
L.H. Wang

Introduction: Statin may induce epithelial dysfunction of the bladder urothelium. Epithelial dysfunction was proposed as one of the major potential etiologies for bladder pain syndrome/interstitial cystitis (BPS/IC). In this study, we examined the association between statin use and BPS/IC using a population-based study. Subjects and Methods: This case-control study used the Taiwan Longitudinal Health Insurance Database. In total, 815 female subjects with BPS/IC and 4075 randomly selected female controls were included. We used a conditional logistic regression to compute the odds ratio (OR) for having previously used statins between cases and controls. Results: A conditional logistic regression analysis showed that the OR of prior statin users for cases was 1.52 (95% confidence interval (CI): 1.19-1.94) compared to controls after adjusting for diabetes, hypertension, coronary heart disease, obesity, chronic pelvic pain, irritable bowel syndrome, fibromyalgia, chronic fatigue syndrome, depression, panic disorder, migraines, sicca syndrome, allergies, endometriosis, and asthma. Furthermore, adjusted ORs of regular and irregular statin use for cases were 1.58 (95% CI: 1.20-2.08) and 1.53 (95% CI: 1.02-2.31), respectively, compared to controls. Conclusion: We concluded that there was an association between statin use and BPS/IC.


Lung Cancer ◽  
2012 ◽  
Vol 75 (3) ◽  
pp. 275-279 ◽  
Author(s):  
Meng-Hsuan Cheng ◽  
Hui-Fen Chiu ◽  
Shu-Chen Ho ◽  
Chun-Yuh Yang

2011 ◽  
Vol 106 (5) ◽  
pp. 894-898 ◽  
Author(s):  
Hui-Fen Chiu ◽  
Shu-Chen Ho ◽  
Chih-Cheng Chen ◽  
Chun-Yuh Yang

Head & Neck ◽  
2019 ◽  
Vol 41 (5) ◽  
pp. 1193-1198 ◽  
Author(s):  
Li‐Ting Kao ◽  
Shih‐Han Hung ◽  
Pai‐Feng Kao ◽  
Ju‐Chi Liu ◽  
Herng‐Ching Lin

BMJ ◽  
2009 ◽  
Vol 338 (jun16 1) ◽  
pp. b2137-b2137 ◽  
Author(s):  
S. Dublin ◽  
M. L Jackson ◽  
J. C Nelson ◽  
N. S Weiss ◽  
E. B Larson ◽  
...  

2012 ◽  
Vol 11 (3) ◽  
pp. 369-374 ◽  
Author(s):  
Hui-Fen Chiu ◽  
Chih-Cheng Chen ◽  
Hsin-Wei Kuo ◽  
I-Ming Lee ◽  
Trong-Neng Wu ◽  
...  

2014 ◽  
Vol 38 (1) ◽  
pp. 42-47 ◽  
Author(s):  
Christina G. Jespersen ◽  
Mette Nørgaard ◽  
Søren Friis ◽  
Charlotte Skriver ◽  
Michael Borre

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