scholarly journals Frequency of renal artery stenosis and associated factors in patients undergoing coronary angiography

2019 ◽  
Vol 8 (2) ◽  
pp. 14-14 ◽  
Author(s):  
Fardin Mirbolouk ◽  
Arsalan Salari ◽  
Asieh Ashouri ◽  
Marjan Mahdavi-Roshan ◽  
Mahboobe Gholipour

Background: Coronary artery disease (CAD) is the first cause of mortality in developed and developing countries, including Iran. Identifying high-risk patients can save many from morbidity and mortality. Renal artery stenosis (RAS) seems to be equivalent to CAD in patients with cardiovascular risk. Objectives: The present study aimed to determine the prevalence, severity, and extent of RAS and its predictors in patients with confirmed CAD on coronary angiography. Patients and Methods: All patients suspected of ischemic heart disease (IHD), who underwent diagnostic coronary angiography at Heshmat heart hospital, Iran were recruited (May 2015 to June 2016). Patients with confirmed CAD underwent non-selective renal angiography, which was categorized as mild, moderate or severe based on luminal diameter narrowing more than normal >0% to 50%, between 50%-70% and more than 70%, respectively. Results: Of 233 patients, RAS was observed in 123 (53%). Around 20% were mild, 10% were moderate and 23% were severe. Additionally, RAS in 37% was unilateral and in 16% were bilateral. Besides,19%, 25% and 56% of patients had atherosclerosis in one, two and three vessels, respectively. There was no correlation between the CAD severity and severity of RAS (P=0.807). Conclusions: Higher prevalence of RAS in patients with hyperlipidemia (60% vs. 40%) was detected. Its association with variables affecting CAD indicates that RAS can be a predictor of CAD. Therefore, simultaneous assessment of RAS in coronary angiography can be a good screening method for CAD beside earlier diagnosis of kidney disease.

2011 ◽  
Vol 5 ◽  
pp. CMC.S6819 ◽  
Author(s):  
Negar Salehi ◽  
Ata Firouzi ◽  
Arash Gholoobi ◽  
Farshad Shakerian ◽  
Hamid-Reza Sanati ◽  
...  

Aims We evaluated the relationship between distribution of lesions in coronary tree and atherosclerotic renal artery stenosis (RAS). Methods and Results Data collected prospectively on 500 consecutive patients who underwent simultaneous renal angiography following coronary angiography. Overall prevalence of RAS was 26.2% (131 patients). Significant (≥ 50% luminal diameter stenosis) RAS was present in 70 patients (14%). In 346 individuals of the study population, significant CAD was present (69.2%). Significant RAS was more common (18.4%) in this group. Older age, higher intra-arterial systolic blood pressure (SBP) and pulse pressure (PP) at the time of catheterization, and 3-vessel coronary artery disease (CAD) were associated with significant RAS in univariate analysis. Relationship between involved locations of coronary arteries [Left anterior descending (LAD), left circumflex (LCX), Right Coronary Artery (RCA), and their ostioproximal portions] and RAS were significant except for left main (LM) disease. In multivariate model, age more than 62 years, SBP greater than 150 mmHg, PP in excess of 60 mmHg and RCA involvement were independent predictors of significant RAS. Conclusion Simultaneous renal angiography following coronary angiography might be justified in patients with significant RCA disease who are older with increased levels of intra-arterial SBP and PP.


PLoS ONE ◽  
2013 ◽  
Vol 8 (3) ◽  
pp. e58635 ◽  
Author(s):  
Thiago A. Macedo ◽  
Rodrigo P. Pedrosa ◽  
Valeria Costa-Hong ◽  
Luiz J. Kajita ◽  
Gustavo R. Morais ◽  
...  

1998 ◽  
Vol 136 ◽  
pp. S82
Author(s):  
Y. Wang ◽  
David S.W. Ho ◽  
W. Yan ◽  
W.H. Chen ◽  
M. Chui ◽  
...  

2009 ◽  
Vol 32 (11) ◽  
pp. 1009-1014 ◽  
Author(s):  
Samad Ghaffari ◽  
Bahram Sohrabi ◽  
Reza Beheshti Siahdasht ◽  
Leili Pourafkari

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Mark Shipeng Yu ◽  
Alan H Matsumoto ◽  
Karol Pencina ◽  
Katherine Tuttle ◽  
Wencan He ◽  
...  

Introduction: Ischemic nephropathy due to atherosclerotic renal artery stenosis (ARAS) is associated with poor event free survival. However, previous studies suggest that stenosis severity has a poor relation to kidney function. We sought to test the interactions of stenosis severity, and revascularization, on kidney function in people with ARAS. Hypothesis: Stenosis severity is associated with poor renal function in people with ARAS. Methods: The Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) clinical trial is a prospective trial of individuals with atherosclerotic renal-artery stenosis. Patients were followed to a maximum of 8 years. Angiographic images were measured at a single core lab (University of Virginia) using quantitative computer-assisted angiography. Estimated glomerular filtration rate (eGFR) was measured using creatinine and cystatin-C, performed at a single core lab (University of Minnesota), and calculated using the CKD-EPI Creatinine-Cystatin C formula. The analyses are controlled by age and gender. Results: At baseline CKD-EPI eGFR was strongly and negatively correlated with percent stenosis (-0.2472, p<0.0001) and positively correlated with minimal luminal diameter (0.2974, p<0.0001). Interestingly, peak systolic pressure gradient and mean pressure gradients were not (p=ns for both). At three years follow-up baseline percent stenosis remained significant by univariate analysis (0.1380, p=0.01), however, it was not significant by multivariate analysis. Conclusions: Stenosis severity is strongly related to kidney function at the time of presentation in patients with atherosclerotic renal artery stenosis. However, by three years follow-up, this relationship appears to be lost.


Vascular ◽  
2018 ◽  
Vol 27 (2) ◽  
pp. 190-198
Author(s):  
Haojian Dong ◽  
Yanqiu Ou ◽  
Zhiqiang Nie ◽  
Wenhui Huang ◽  
Yuan Liu ◽  
...  

Objective Data about renal artery stenosis association with left ventricular remodeling in patients coexisting with coronary artery disease are scanty. Methods Patients with suspected both coronary artery disease and renal artery stenosis undergoing coronary and renal arteriography between October 2013 and December 2015 were prospectively enrolled. Left ventricular remodeling patterns were compared among different severity of renal artery stenosis group. Logistic regression was done to investigate the determinants of the left ventricular morphology. Results The overall prevalence of left ventricular hypertrophy was 40.5%, the highest in bilateral renal artery stenosis group compared to unilateral or normal ones (65.4% versus 41.8% versus 34.8%, p = 0.012). Significantly lower estimated glomerular filtration rate and higher cystatin C level were found in bilateral renal artery stenosis group than that in other two groups. Multivariate regression analysis showed that bilateral renal artery stenosis was associated with increased left ventricular hypertrophy and concentric hypertrophy with statistical significance (adjusted odds ratio = 2.909 (95%CI: 1.063–7.961), and 3.021 (95%CI: 1.136–8.033)). In addition, estimated glomerular filtration rate level was also related to left ventricular hypertrophy, while there was no significant interaction between renal artery stenosis and coronary artery disease on left ventricular hypertrophy/concentric hypertrophy occurrence. Conclusions Bilateral renal artery stenosis is significantly associated with increased left ventricular hypertrophy/concentric hypertrophy in patients with suspected concomitant coronary and renal artery disease, while no synergic effect could be found in coronary artery disease.


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