scholarly journals Differential Longitudinal Changes in Cortical Thickness, Surface Area and Volume across the Adult Life Span: Regions of Accelerating and Decelerating Change

2014 ◽  
Vol 34 (25) ◽  
pp. 8488-8498 ◽  
Author(s):  
A. B. Storsve ◽  
A. M. Fjell ◽  
C. K. Tamnes ◽  
L. T. Westlye ◽  
K. Overbye ◽  
...  
1994 ◽  
Vol 35 (4) ◽  
pp. 373-377 ◽  
Author(s):  
Sterling C. Johnson ◽  
Tamra Farnworth ◽  
James B. Pinkston ◽  
Erin D. Bigler ◽  
Duane D. Blatter

2019 ◽  
Vol 50 (3) ◽  
pp. 422-430 ◽  
Author(s):  
Dongtao Wei ◽  
Kangcheng Wang ◽  
Jie Meng ◽  
Kaixiang Zhuang ◽  
Qunlin Chen ◽  
...  

AbstractBackgroundImaging studies have shown that the subcallosal region (SCR) volume was decreased in patients with major depressive disorder (MDD). However, whether the volumetric reductions in the SCR are due to thinning of the cortex or a loss of surface area (SA) remains unclear. In addition, the relationship between cortical measurements of the SCR and age through the adult life span in MDD remains unclear.MethodsWe used a cross-sectional design from 114 individuals with MDD and 112 matched healthy control (HC) individuals across the adult life span (range: 18–74 years). The mean cortical volume (CV), SA and cortical thickness (CT) of the SCR were computed using cortical parcellation based on FreeSurfer software. Multivariate analyses of covariance models were performed to compare differences between the MDD and HC groups on cortical measurements of the SCR. Multiple linear regression models were used to test age-by-group interaction effects on these cortical measurements of the SCR.ResultsThe MDD had significant reductions in the CV and SA of the left SCR compared with HC individuals after controlling of other variables. The left SCR CV and SA reductions compared with matched controls were observed only in early adulthood patients. We also found a significant age-related CT reduction in the SCR both in the MDD and HC participants.ConclusionsThe SCR volume reduction was mainly driven by SA in MDD. The different trajectories between the CT and SA of the SCR with age may provide valuable information to distinguish pathological processes and normal ageing in MDD.


1996 ◽  
Vol 41 (6) ◽  
pp. 590-591
Author(s):  
Barbara R. Bjorklund
Keyword(s):  

2006 ◽  
Vol 21 (2) ◽  
pp. 303-317 ◽  
Author(s):  
Carol Magai ◽  
Nathan S. Consedine ◽  
Yulia S. Krivoshekova ◽  
Elizabeth Kudadjie-Gyamfi ◽  
Renee McPherson

2008 ◽  
Author(s):  
Katie Finley ◽  
Joan C. Borod ◽  
Adam Brickman ◽  
J. M. Schmidt ◽  
Stephanie Assuras ◽  
...  

2008 ◽  
Author(s):  
Sandra Hale ◽  
Mitchell S. Sommers ◽  
Joel Myerson ◽  
Nancy Tye-Murray ◽  
Nathan Rose ◽  
...  

2006 ◽  
Author(s):  
Mark E. Faust ◽  
Kristi S. Multhaup ◽  
Patricia A. Brooks ◽  
Sarah Frey ◽  
Blair Hicks ◽  
...  

Author(s):  
Michael W. Pratt ◽  
M. Kyle Matsuba ◽  
Heather L. Lawford ◽  
Feliciano Villar

This chapter addresses the development of generativity, Erikson’s conception of the midlife strength in his eight-stage model of personality development. Following Erikson, the authors define generativity as care for next generations and set it in the context of both personality theory and life span development. Specifically, the authors draw on the framework of McAdams that characterizes personality as composed of three sequentially developing levels: actions, goals/motives, and the narrative life story (a mature form of narrative that provides the self with a sense of meaning and identity). The authors then review research on generativity as expressed from adolescence to later adulthood, which indicates that it is a relevant construct across this entire period in a variety of life domains. They also consider factors influencing generativity levels, including family background and cultural variations. Throughout the chapter, the authors consider the connections of generativity to morality across different facets of personality and stages of the adult life span.


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