scholarly journals BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells

2018 ◽  
Vol 38 (7) ◽  
pp. 1662-1676 ◽  
Author(s):  
Vukasin M. Jovanovic ◽  
Ahmad Salti ◽  
Hadas Tilleman ◽  
Ksenija Zega ◽  
Marin M. Jukic ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Dopaminergic Neurons ◽  
Smad Pathway ◽  
Midbrain Dopaminergic Neurons ◽  
Induced Pluripotent

scholarly journals In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formation

PLoS ONE ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. e0170735 ◽  
Author(s):  
Hyun Woo Choi ◽  
Yean Ju Hong ◽  
Jong Soo Kim ◽  
Hyuk Song ◽  
Ssang Gu Cho ◽  
...  
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
In Vivo Differentiation ◽  
Induced Pluripotent

scholarly journals Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells

2013 ◽  
Vol 110 (7) ◽  
pp. E602-E610 ◽  
Author(s):  
E. R. Andersson ◽  
C. Salto ◽  
J. C. Villaescusa ◽  
L. Cajanek ◽  
S. Yang ◽  
...  
Keyword(s):  
Stem Cells ◽  
Dopaminergic Neurons ◽  
Midbrain Dopaminergic Neurons

scholarly journals Transmission Mechanism of Lewy Body-Like α-Synucleinopathies in Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells

2018 ◽  
Vol 4 ◽  
pp. e25423
Author(s):  
Cheng Lin
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Dopaminergic Neurons ◽  
Lewy Body ◽  
Lewy Bodies ◽  
Transmission Mechanism ◽  
Induced Pluripotent

Grafting of cells in Parkinson's disease (PD) results in a prion-like infection, exhibiting a Lewy body-like pathology, caused by the recipient cells. The transmission mechanism of Lewy bodies is not completely understood. Therefore, a research idea with a novel experimental strategy is proposed to investigate the transmission mechanism of α-synuclein pathology using PD patient-derived human induced pluripotent stem cells (hiPSC) in an in vitro human cellular and molecular PD model and in vivo mouse PD model for dopaminergic neuron transplantation.

Midbrain Dopaminergic Neurons Differentiated from Human-Induced Pluripotent Stem Cells

2019 ◽  
pp. 97-118 ◽  
Author(s):  
Fabiano Araújo Tofoli ◽  
Ana Teresa Silva Semeano ◽  
Ágatha Oliveira-Giacomelli ◽  
Maria Carolina Bittencourt Gonçalves ◽  
Merari F. R. Ferrari ◽  
...  
Keyword(s):  
Stem Cells ◽  
Induced Pluripotent Stem Cells ◽  
Pluripotent Stem Cells ◽  
Dopaminergic Neurons ◽  
Midbrain Dopaminergic Neurons ◽  
Induced Pluripotent
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