EFFECT OF D-THYROXINE ON THE TENSILE STRENGTH OF HEALING WOUNDS

ABSTRACT The effect of reserpine, 5-hydroxytryptamine (5-HT), polymyxin B and fasting on the mast cells and tensile strength of healing wounds has been investigated. Reserpine and polymyxin B were given during the last three days before the wounds were inflicted, while 5-HT was given as daily injections after the incisions. Reserpine and – to a lesser extent – 5-HT caused a significant decrease in the tensile strength of the wounds. This decrease was probably not caused by the concomitant weight-loss since a group of fasted animals which showed the same weight-loss turned out to have a normal tensile strength. The animals treated with polymyxin B showed no significant decrease in tensile strength. Treatment with reserpine and 5-HT was not followed by any significant changes in the mast cell morphology, while polymyxin B caused marked changes, the nature of which could not be determined. It is concluded that the decrease in tensile strength of healing wounds induced by 5-HT and reserpine is probably not mediated by the tissue mast cell.

Download Full-text

Diphenylhydantoin sodium promotes early and marked angiogenes is and results in increased collagen deposition and tensile strength in healing wounds

Surgery ◽

10.1016/s0039-6060(98)70181-3 ◽

1998 ◽

Vol 123 (3) ◽

pp. 287-293 ◽

Cited By ~ 30

Author(s):

Marc L. DaCosta ◽

Mark C. Regan ◽

Mohamed Al Sader ◽

Mary Leader ◽

David Bouchier-Hayes

Keyword(s):

Tensile Strength ◽

Collagen Deposition ◽

Healing Wounds

Download Full-text

Phase Transformations in Ti-7w/oMo-3w/oMe Alloy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100052584 ◽

1974 ◽

Vol 32 ◽

pp. 514-515

Author(s):

S. Fujishiro

Keyword(s):

Electron Microscopy ◽

Mechanical Properties ◽

Transmission Electron Microscopy ◽

Tensile Strength ◽

Mechanical Processing ◽

Ray Method ◽

X Ray ◽

Transmission Electron ◽

Water Quench ◽

Alpha Beta

The mechanical properties of three titanium alloys (Ti-7Mo-3Al, Ti-7Mo- 3Cu and Ti-7Mo-3Ta) were evaluated as function of: 1) Solutionizing in the beta field and aging, 2) Thermal Mechanical Processing in the beta field and aging, 3) Solutionizing in the alpha + beta field and aging. The samples were isothermally aged in the temperature range 300° to 700*C for 4 to 24 hours, followed by a water quench. Transmission electron microscopy and X-ray method were used to identify the phase formed. All three alloys solutionized at 1050°C (beta field) transformed to martensitic alpha (alpha prime) upon being water quenched. Despite this heavily strained alpha prime, which is characterized by microtwins the tensile strength of the as-quenched alloys is relatively low and the elongation is as high as 30%.

Download Full-text