AN UNUSUAL CASE OF VITAMIN D TOXICITY

1967 ◽  
Vol 54 (2) ◽  
pp. 380-384 ◽  
Author(s):  
F. H. Sterling ◽  
J. J. Rupp

ABSTRACT A case of marked sensitivity to vitamin D, is discussed. The reason for the occurrence of hypercalcaemic crisis three weeks after the beginning of treatment with 100 000 units of vitamin D is unknown. The possibility that either lack of thyrocalcitonin or synergism with a tumour produced parathormone-like substance played a role in the hypersensitivity to calciferol is suggested. The important but rarely reported electrocardiographic pattern of extreme hypercalcaemia was noted.

PEDIATRICS ◽  
1976 ◽  
Vol 57 (5) ◽  
pp. 794-797
Author(s):  
Matthew H. Connors ◽  
Bagher M. Sheikholislam ◽  
Julian J. Irias

Attempts at management of idiopathic hypoparathyroidism with vitamin D have led to various reports of resistance to therapy,1 different responses to vitamin D preparations,2 and unexplained toxicity.3 We report a patient with idiopathic hypoparathyroidism who was persistently hypocalcemic during ten months of treatment with vitamin D, 150,000 units/day. After voluntary weight reduction he became hypercalcemic on the same dose of vitamin D. We believe that the toxicity in this instance was due to release of stored vitamin D into the circulation. CASE REPORT The patient was referred to the hospital at 12½ years of age because of intracranial calcifications noted on roentgenograms obtained for the evaluation of sinusitis.


1979 ◽  
Vol 13 (12) ◽  
pp. 1383-1386
Author(s):  
Gary M Chan ◽  
John J Buchino ◽  
Reginald Tsang

Author(s):  
Hemamalini Ketha ◽  
Heather Wadams ◽  
Aida Lteif ◽  
Ravinder J. Singh

2019 ◽  
Vol 12 (2) ◽  
pp. bcr-2017-223415 ◽  
Author(s):  
Nandakrishna Bolanthakodi ◽  
Sudha Vidyasagar ◽  
Muralidhar Varma ◽  
Avinash Holla

Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiological entity described by Hinchey et al in late 90’s, characterised by variable associations of seizure activity, consciousness impairment ranging from confusion to coma, headaches, visual abnormalities, nausea/vomiting and focal neurological signs. Common causes are accelerated hypertension, eclampsia, preeclampsia, cytotoxic drug use and autoimmune diseases like systemic lupus erythematosus.We report a case of PRES in a 62-year-old female patient due to hypercalcemia secondary to vitamin D toxicity on treatment with calcium supplements and vitamin D for secondary hypoparathyroidism. She had seizures and visual defects on presentation which recovered completely with treatment of hypercalcemia.


2019 ◽  
Vol 191 (27) ◽  
pp. E769-E769
Author(s):  
Nipith Charoenngam ◽  
Arash Hossein-Nezhad ◽  
David A. Hanley ◽  
Michael F. Holick
Keyword(s):  

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