CUSHING'S SYNDROME ASSOCIATED WITH A »CORTICOTROPHIN«-PRODUCING BRONCHIAL NEOPLASM
Keyword(s):
ABSTRACT A patient is reported who developed bilateral adrenal hyperplasia and Cushing's syndrome in association with an undifferentiated bronchial carcinoma. »Corticotrophin« was demonstrated by radioimmunoassay in the tumour and its metastases and »melanocyte-stimulating hormone« by bioassay in a metastasis. Treatment with Metyrapone resulted in bio-chemical evidence of improvement but side-effects limited its clinical usefulness. The use of pituitary-adrenal function tests in distinguishing patients with this syndrome from those with Cushing's disease is discussed.
1962 ◽
Vol 41
(10)
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pp. 1871-1885
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1979 ◽
Vol 16
(1-6)
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pp. 86-88
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1973 ◽
Vol 36
(3)
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pp. 433-438
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