Diurnal administration of human growth hormone-releasing factor does not modify sleep and sleep-related growth hormone secretion in normal young men

1985 ◽  
Vol 110 (2) ◽  
pp. 158-163 ◽  
Author(s):  
Philippe Garry ◽  
Bernard Roussel ◽  
Richard Cohen ◽  
Sylviane Biot-Laporte ◽  
Abdel Elm Charfi ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Young Adult ◽  
Human Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Human Growth ◽  
Adult Males ◽  
Growth Hormone Releasing Factor ◽  
Gh Secretion ◽  
Sleep Parameters

Abstract. hGRF (iv 50 μg) was administered to 6 normal young adult males at 09.00 and 20.00 h on different days. Nocturnal GH secretion was monitored during polygraphic sleep recordings on both control nights and nights following hGRF administration. Sleep-related GH secretion and sleep parameters were not affected by diurnal hGRF administration.

Dissociation between circulating concentrations of immunoreactive growth hormone releasing factor and growth hormone in normal human subjects

1987 ◽  
Vol 72 (2) ◽  
pp. 181-185 ◽  
Author(s):  
A. M. Sopwith ◽  
Elizabeth S. Penny ◽  
N. Lytras ◽  
G. M. Besser ◽  
Lesley H. Rees
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Human Subjects ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Human Growth ◽  
Normal Subjects ◽  
Peripheral Circulation ◽  
Growth Hormone Releasing Factor ◽  
Specific Radioimmunoassay

1. Using a highly specific radioimmunoassay we have measured immunoreactive human growth hormone releasing factor (ir-hGRF) concentrations in the peripheral circulation of a total of 12 normal subjects. 2. Neither insulin-induced hypoglycaemia, intravenous arginine nor oral carbohydrate caused any change in venous plasma ir-hGRF concentrations, despite the expected stimulation and suppression respectively of growth hormone secretion. 3. Growth hormone secretion was not increased by oral fat or protein but each of these two foods stimulated ir-hGRF concentrations two- to fourfold. 4. Spontaneous pulses of growth hormone secretion on control days were unaccompanied by any increase in plasma ir-hGRF. 5. The dissociation between peripheral circulating ir-hGRF and growth hormone responses demonstrated under different circumstances suggests that an important source of human growth hormone releasing factor lies outside the hypothalamus and that secretion from this source is unconnected with the normal control of pituitary growth hormone secretion.

scholarly journals Effects of Human Growth Hormone-Releasing Factor and Its Analogs on Growth Hormone Secretion in Cattle and Sheep

1985 ◽  
Vol 56 (9) ◽  
pp. 744-750
Author(s):  
Koichi HODATE ◽  
Tetsu JOHKE ◽  
Asao KAWABATA ◽  
Hiroshi FUSE ◽  
Shinichi OHASHI ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Human Growth ◽  
Growth Hormone Releasing Factor ◽  
Cattle And Sheep

The regulation of insulin-induced and sleep-related human growth hormone secretion: A review

1979 ◽  
Vol 4 (4) ◽  
pp. 341-349 ◽  
Author(s):  
Wallace B. Mendelson ◽  
Laurence S. Jacobs ◽  
J.Christian Gillin ◽  
Richard Jed Wyatt
Keyword(s):  
Growth Hormone ◽  
Human Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Human Growth
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