Bone health status in Indian children with type 1 diabetes as assessed by peripheral quantitative computer tomography (pQCT)

2017 ◽  
Author(s):  
Rubina Mandlik ◽  
Veena Ekbote ◽  
Shital Bhor ◽  
Neha Kajale ◽  
Jwala Pawar ◽  
...  
Author(s):  
Marco Janner ◽  
Christoph Saner

This paper gives an overview of the impact of type 1 diabetes on bone health in children and adolescents. First, we analyse studies using DXA (dual x-ray absorptiometry) to assess BMC (bone mineral content) and BMD (bone mineral density). Then, we discuss modern, non-invasive techniques including pQCT (peripheral quantitative computer tomography) and HRpQCT (high-resolution peripheral quantitative computer tomography) for the detailed assessment of bone health aspects including bone mass, bone geometry, bone microarchitecture and bone strength. Thereafter, we explore some of the mechanisms that are responsible for diabetic bone disease in children, like low bone turnover and high sclerostin levels. Finally, we summarise some of the evidence for the importance of microvascular disease in the pathophysiology of diabetic bone disease.


2013 ◽  
Author(s):  
Parthasarathy Lavanya ◽  
Khadilkar Anuradha ◽  
Ekbote Veena ◽  
Chiplonkar Shashi ◽  
Mughal Zulf ◽  
...  

2021 ◽  
Vol 12 (2) ◽  
pp. 182
Author(s):  
SrideviA Naaraayan ◽  
RaghavanV Dhakshayani ◽  
Rema Chandramohan

2018 ◽  
Vol 25 (4) ◽  
pp. 231-236 ◽  
Author(s):  
Viral N. Shah ◽  
R. Dana Carpenter ◽  
Virginia L. Ferguson ◽  
Ann V. Schwartz
Keyword(s):  

2019 ◽  
Vol 31 (2) ◽  
pp. 153-161 ◽  
Author(s):  
Kawther Elissa ◽  
Ewa-Lena Bratt ◽  
Åsa B Axelsson ◽  
Salam Khatib ◽  
Carina Sparud-Lundin

Introduction: Self-perceived health status and sense of coherence (SOC) are essential constructs for capturing health outcomes in children with type 1 diabetes (T1D). This study measured self-perceived health status and SOC in children with T1D and compared them with a healthy reference group in West Bank, Palestine. Methodology: One hundred children with T1D aged 8 to 18 years and 300 healthy children completed PedsQL 4.0 Generic Core Scales and SOC-13 in a cross-sectional descriptive study. Results: All children reported acceptable self-perceived health status and low degree of SOC. In the diabetes group, high degree of SOC was associated with better self-perceived health status and more optimal metabolic control. Males in the diabetes group reported higher self-perceived health status than females. Discussion: The unstable political situation in Palestine may threaten SOC in children in general. Health professionals can monitor self-perceived health status and SOC to evaluate interventions aiming to improve glycemic control.


2020 ◽  
Vol 21 (6) ◽  
pp. 987-994
Author(s):  
Nikhil Shah ◽  
Anuradha Khadilkar ◽  
Ketan Gondhalekar ◽  
Vaman Khadilkar

2012 ◽  
Vol 29 (6) ◽  
pp. 716-720 ◽  
Author(s):  
P. D. Home ◽  
L. Meneghini ◽  
U. Wendisch ◽  
R. E. Ratner ◽  
T. Johansen ◽  
...  

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