Comparative steroid profiling in large animals

Background: Veterinary work is considered high risk and involves working with a range of hazards including large animals, high workload and long hours. A key potential hazard is making home visits and providing out of hours emergency care where vets often work alone, without support, and must travel long distances. The current study aimed to examine UK veterinary perceptions of safety climate, lone working and on-call tasks to gain a deeper understanding of the risk and hazards involved. Method: An online mixed-methods survey was used to gather quantitative data relevant to practice safety climate, and qualitative data regarding veterinary perception of lone working and on-call work. A sample of 76 UK veterinarians were recruited.Results: The quantitative results suggest that there may be practice safety climate issues around a lack of communication and discussion pertaining to safety, particularly in terms of maintaining personal safety. Key themes within the qualitative data included feeling pressure to treat patients, dealing with difficult clients, travel concerns and feeling unsafe when meeting clients alone and in remote locations. Conclusion: These findings indicate that personal safety requires more attention and discussion within veterinary practices, and that safety protocols and requirements should be shared with clients.

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Specification for tracheal tubes for large animals in veterinary anaesthesia

10.3403/02328144 ◽

1990 ◽

Keyword(s):

Large Animals

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Work Guidelines - Working with Large Animals

10.21636/nfmc.nccrahs.youthwork.workanimals.g.2017 ◽

2017 ◽

Author(s):

Keyword(s):

Large Animals

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Contribution of Large Animals to Translational Research on Prenatal Programming of Obesity and Associated Diseases

Current Pharmaceutical Biotechnology ◽

10.2174/1389201018666170811150920 ◽

2017 ◽

Vol 18 (7) ◽

Cited By ~ 10

Author(s):

Antonio Gonzalez-Bulnes ◽

Pascale Chavatte-Palmer

Keyword(s):

Translational Research ◽

Prenatal Programming ◽

Associated Diseases ◽

Large Animals

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Surgical management of choke through oesophagotomy in a buffalo: A case report

THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY ◽

10.21887/ijvsbt.v12i3.7098 ◽

2017 ◽

Vol 12 (3) ◽

Author(s):

Devasee Borakhatariya ◽

A. B. Gadara

Keyword(s):

Case Report ◽

Surgical Management ◽

Clinical Presentation ◽

Clinical Signs ◽

Thoracic Inlet ◽

Cervical Oesophagus ◽

Foreign Objects ◽

History Of ◽

Oesophageal Obstruction ◽

Large Animals

Oesophageal disorders are relatively uncommon in large animals. Oesophageal obstruction is the most frequently encountered clinical presentation in bovine and it may be intraluminal or extra luminal (Haven, 1990). Intraluminal obstruction or “choke” is the most common abnormality that usually occurs when foreign objects, large feedstuff, medicated boluses, trichobezoars, or oesophageal granuloma lodge in the lumen of the oesophagus. Oesophageal obstructions in bovine commonly occur at the pharynx, the cranial aspect of the cervical oesophagus, the thoracic inlet, or the base of the heart (Choudhary et al., 2010). Diagnosis of such problem depends on the history of eating particular foodstuff and clinical signs as bloat, tenesmus, retching, and salivation

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Assessment of Electrospun Pellethane-Based Scaffolds for Vascular Tissue Engineering

Materials ◽

10.3390/ma14133678 ◽

2021 ◽

Vol 14 (13) ◽

pp. 3678

Author(s):

Vera Chernonosova ◽

Alexandr Gostev ◽

Ivan Murashov ◽

Boris Chelobanov ◽

Andrey Karpenko ◽

...

Keyword(s):

Vascular Tissue ◽

Ex Vivo ◽

Vascular Grafts ◽

Wistar Rat ◽

Graft Occlusion ◽

Suitable Candidate ◽

Large Animals ◽

Cell Adhesion And Proliferation

We examined the physicochemical properties and the biocompatibility and hemocompatibility of electrospun 3D matrices produced using polyurethane Pellethane 2363-80A (Pel-80A) blends Pel-80A with gelatin or/and bivalirudin. Two layers of vascular grafts of 1.8 mm in diameter were manufactured and studied for hemocompatibility ex vivo and functioning in the infrarenal position of Wistar rat abdominal aorta in vivo (n = 18). Expanded polytetrafluoroethylene (ePTFE) vascular grafts of similar diameter were implanted as a control (n = 18). Scaffolds produced from Pel-80A with Gel showed high stiffness with a long proportional limit and limited influence of wetting on mechanical characteristics. The electrospun matrices with gelatin have moderate capacity to support cell adhesion and proliferation (~30–47%), whereas vascular grafts with bivalirudin in the inner layer have good hemocompatibility ex vivo. The introduction of bivalirudin into grafts inhibited platelet adhesion and does not lead to a change hemolysis and D-dimers concentration. Study in vivo indicates the advantages of Pel-80A grafts over ePTFE in terms of graft occlusion, calcification level, and blood velocity after 6 months of implantation. The thickness of neointima in Pel-80A–based grafts stabilizes after three months (41.84 ± 20.21 µm) and does not increase until six months, demonstrating potential for long-term functioning without stenosis and as a suitable candidate for subsequent preclinical studies in large animals.

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