The Prevalence and Extent of Coronary Atherosclerosis among Patients with a Zero Calcium Score and the Influence of Patient Characteristics

2013 ◽  
Vol 16 (4) ◽  
pp. 198 ◽  
Author(s):  
Guray Oncel ◽  
Dilek Oncel
Keyword(s):  
Risk Factors ◽  
Coronary Artery ◽  
Obstructive Coronary Artery Disease ◽  
Calcium Score ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Calcium Scoring ◽  
Symptom Status ◽  
Artery Disease ◽  
Zero Calcium Score

<p><b>Purpose:</b> Coronary artery calcium (CAC) is a specific indicator of and an independent risk factor for atherosclerosis; however, calcium scoring may miss noncalcified plaques, which may have clinical importance. The aim of this study was both to identify the presence and extent of coronary plaques during computed tomography coronary angiography (CTCA) in patients with a zero CAC score and to evaluate the effect of risk factors and symptom status on the presence of noncalcified plaques.</p><p><b>Materials and Methods:</b> In this retrospective study, we analyzed the cases of 842 consecutive patients between October 2006 and November 2011. Of these patients, we included 357 with a zero calcium score in the study. Information regarding patient age, sex, coronary risk factors, and symptom status were recorded. Coronary calcium-scoring scans were followed by CTCA. The calcium scores were calculated, and the presence of noncalcified plaques and significant stenoses (>50% of vessel diameter) was evaluated.</p><p><b>Results:</b> Of the 357 patients with a zero calcium score, 37 (10.36%) had atherosclerotic plaques; 9 patients (2.52%) had significant coronary stenosis. Among coronary risk factors, only diabetes mellitus was significantly correlated with any risk factors (presence of atherosclerosis and obstructive coronary artery disease; <i>P</i> = .030 and .013, respectively).</p><p><b>Conclusion:</b> Although CAC scoring is a safe and a reliable test to exclude obstructive coronary artery disease, the absence of CAC does not definitively exclude the presence of atherosclerosis. CTCA is a more appropriate method for determining the atheroma burden.</p>

Correlation between Coronary Risk Factors and Severity of Coronary Artery Disease

1995 ◽  
Vol 25 (6) ◽  
pp. 1099
Author(s):  
Ki Bae Seung ◽  
Doo Soo Jeon ◽  
Dong Hun Kang ◽  
Hui Kyung Jeon ◽  
Yong Ju Kim ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Artery Disease

Coronary risk factors in children of parents with premature coronary artery disease

1993 ◽  
Vol 82 (2) ◽  
pp. 162-165 ◽  
Author(s):  
Y Beigel ◽  
J George ◽  
L Leibovici ◽  
A Mattityahu ◽  
S Sclarovsky ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Premature Coronary Artery Disease ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Artery Disease

Abstract 5752: Epicardial Fat Assessed by Multi-Detector Computed Tomography (mdct) is a New Risk Factor of Coronary Artery Disease in Non-Obese Patients

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Tadateru Iwayama ◽  
Joji Nitobe ◽  
Mitsunori Ishino ◽  
Harutoshi Tamura ◽  
Tetsurou Shishido ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Epicardial Fat ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Obese Patients ◽  
Epicardial Fat Volume ◽  
Artery Disease ◽  
Fat Volume

Objective: An increment of abdominal visceral fat has been reported to be a coronary risk factor associated with metabolic syndrome. However, adipose tissue surrounding heart has not been fully determined as coronary risk factors. Accurate volumetric measurement of epicardial fat can be easily obtained by MDCT. We examined the relationship between epicardial fat volume and clinical parameters in patients with coronary artery disease (CAD). Method: We evaluated epicardial fat volume by 64 detector row CT scanner in CAD patients (obese, 13; non-obese, 11 patients) who underwent elective coronary artery bypass graft surgery and in non-CAD patients who showed normal coronary arteries on angiography (obese, 3; non-obese, 11 patients). Epicardial fat volume was obtained as the sum of fat areas on short axis images. Obese patients were defined as over 25 in body mass index (BMI). Result: Epicardial fat volume was significantly higher in patients with CAD than in those without CAD (40.6 ± 14.7 ml vs. 20.0 ± 14.7 ml, p < 0.05). Epicardial fat volume was not correlated to following coronary risk factors such as HbA1c, fasting plasma glucose, lipid and blood pressure except for BMI. Although there was no difference epicardial fat volume between in obese patients with CAD and in those without CAD (48.3 ± 27.9 ml vs. 41.2 ± 11.0 ml, NS), it was significantly higher in non-obese patients with CAD than in those without CAD (32.1 ± 9.2 ml vs. 14.2 ± 9.2 ml, p < 0.05). Conclusions: The quantity of epicardial fat using MDCT is related with the presence of CAD. Especially in non-obese patients, epicardial fat may affect directly progression of CAD independent of pathophysiological process of metabolic syndrome.

scholarly journals Relationship Between Endothelial Function and Coronary Risk Factors in Patients With Stable Coronary Artery Disease

2007 ◽  
Vol 71 (5) ◽  
pp. 698-702 ◽  
Author(s):  
Cevat Kirma ◽  
Mustafa Akcakoyun ◽  
Ali Metin Esen ◽  
Irfan Barutcu ◽  
Osman Karakaya ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Endothelial Function ◽  
Stable Coronary Artery Disease ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Artery Disease

scholarly journals Prevalence of coronary artery disease and coronary risk factors in rural and urban populations of north India

1997 ◽  
Vol 18 (11) ◽  
pp. 1728-1735 ◽  
Author(s):  
R. B. Singh ◽  
J. P. Sharma ◽  
V. Rastogi ◽  
R. S. Raghuvanshi ◽  
M. Moshiri ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
North India ◽  
Coronary Risk Factors ◽  
Coronary Risk ◽  
Urban Populations ◽  
Rural And Urban ◽  
Artery Disease
Sign in / Sign up

Export Citation Format

Share Document