scholarly journals Involving Undergraduates in the Annotation and Analysis of Global Gene Expression Studies: Creation of a Maize Shoot Apical Meristem Expression Database

Genetics ◽  
2007 ◽  
Vol 176 (2) ◽  
pp. 741-747 ◽  
Author(s):  
Brent Buckner ◽  
Jon Beck ◽  
Kate Browning ◽  
Ashleigh Fritz ◽  
Lisa Grantham ◽  
...  
2008 ◽  
Vol 68 (2) ◽  
pp. 447-452 ◽  
Author(s):  
CA. Sommer ◽  
F. Henrique-Silva

Even though the molecular mechanisms underlying the Down syndrome (DS) phenotypes remain obscure, the characterization of the genes and conserved non-genic sequences of HSA21 together with large-scale gene expression studies in DS tissues are enhancing our understanding of this complex disorder. Also, mouse models of DS provide invaluable tools to correlate genes or chromosome segments to specific phenotypes. Here we discuss the possible contribution of HSA21 genes to DS and data from global gene expression studies of trisomic samples.


2017 ◽  
Author(s):  
Weiguang Mao ◽  
Elena Zaslavsky ◽  
Boris M. Hartmann ◽  
Stuart C. Sealfon ◽  
Maria Chikina

AbstractA major challenge in gene expression analysis is to accurately infer relevant biological insight, such as regulation of cell type proportion or pathways, from global gene expression studies. We present a general solution for this problem that outperforms available cell proportion inference algorithms, and is more widely useful to automatically identify specific pathways that regulate gene expression. Our method improves replicability and biological insight when applied to trans-eQTL identification.


2021 ◽  
Author(s):  
Zachary D. Johnson ◽  
Dennis D. Krutkin ◽  
Pavlo Bohutskyi ◽  
Marina G. Kalyuzhnaya

2007 ◽  
Vol 52 (3) ◽  
pp. 391-404 ◽  
Author(s):  
Kazuhiro Ohtsu ◽  
Marianne B. Smith ◽  
Scott J. Emrich ◽  
Lisa A. Borsuk ◽  
Ruilian Zhou ◽  
...  

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