Study of TIMI-II Prognostic Criteria in Stemi

The modern sonographic approach to define miscarriage in early pregnancy was shown in the article. Ultrasound diagnostic and prognostic criteria of nonviable pregnancy in early gestation were introduced. Special attention was paid to the examination`s algorithm and repeatability of ultrasound scans with suspicion of intrauterine pregnancy of uncertain viability. Also the consequences of non-following the stringent ultrasound criteria, which lead to the abortions of potentially normal pregnancies were described. Furthermore, the authors highlighted the importance of safety regulation`s aspects in ultrasound examination in early gestation. The conclusion of the importance and need in following the uniform methodological criteria in diagnostics of nonviable pregnancy has been drawn according to the analysis of world experience.

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Mechanisms of Hepatocyte Injury, Multiorgan Failure, and Prognostic Criteria in Acute Liver Failure

Seminars in Liver Disease ◽

10.1055/s-2003-42639 ◽

2003 ◽

Vol 23 (3) ◽

pp. 203-216 ◽

Cited By ~ 66

Keyword(s):

Liver Failure ◽

Acute Liver Failure ◽

Multiorgan Failure ◽

Prognostic Criteria ◽

Hepatocyte Injury

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Prognostic criteria for Polar Lows

10.5194/egusphere-egu21-12282 ◽

2021 ◽

Author(s):

Natalia Vazaeva ◽

Otto Chkhetiani ◽

Michael Kurgansky

Keyword(s):

Numerical Simulation ◽

Wind Velocity ◽

Large Scale ◽

Satellite Image ◽

Development Stage ◽

Mature Stage ◽

Initial Development ◽

Polar Lows ◽

Prognostic Criteria ◽

Main Challenge

Polar lows (PLs) are important mesoscale (horizontal diameter up to 1000 km) maritime weather systems at high latitudes, forming pole ward from the polar front. We consider the possible prognostic criteria of PLs, in particular, the kinematic helicity as a quadratic characteristic related to the integral vortex formations and the kinematic vorticity number (KVN). To calculate such characteristics we use reanalysis data and the results of numerical simulation with the WRF-ARW model (Version 4.1.) for the PLs over the Nordic (Norwegian and Barents) seas. For comparison, experimental data are used.Our estimate of helicity is based on the connection of an integral helicity (IH) in the Ekman layer with the geostrophic wind velocity, due to the good correlation between IH and half the sum of the wind velocity squared. We have chosen IH averaged over preselected area covering the locality of PLs genesis. This area was moving along with the centre of PL during the numerical simulation.The genesis of PLs can be divided into three stages: (i) an initial development stage, in which a number of small vortices appear in a shear zone; (ii) a late development stage, characterized by the merger of vortices; (iii) a mature stage, in which only a single PL is present. Approximately one day before PL formation, a significant increase in helicity was observed. The average helicity bulk density of large-scale motions has values of 0.3 &#8211; 0.4 ms-2. The local changes in helicity are adjacent to the front side of the PLs. The IH criterion described facilitates the identification of the PLs genesis area. For a more detailed analysis of the PL genesis, it is recommended to apply KVN, which is the additional indicator of PL size and intensity. At the moment of maximum intensity of PLs KVN can reach values of 12 &#8211; 14 units. The advantage of using KVN is also in its clear change directly in the centre of the emerging PLs, which allows to precisely indicates the limits of the most intense part of PLs.The main challenge is to make the operational forecast of PLs possible through the selection of the prognostic integral characteristics of PLs, sufficient for PLs identification and for analysis of their size and intensity in a convenient, usable and understandable way. The criteria associated with vorticity and helicity are reflected in the PLs genesis and development quite clearly. At this time, such a claim is only a hypothesis, which must be tested using a larger set of cases. Future work will need to extend these analyses to other active PL basins. Also, it would be interesting to compare the representation of PLs by using any other criteria. It is intended to use our combined criteria as a precursor to machine learning-based PLs identification procedure where satellite image analysis and capture of particular cloud patterns are currently applied in most of the cases. It would eliminate the time consuming first stage of collecting data sets.This work was supported by the Russian Science Foundation (project No. 19-17-00248).

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The Susceptibility of Meningococci to the Antimicrobial Agents in Moscow 2006 - 2015

Epidemiology and Vaccinal Prevention ◽

10.31631/2073-3046-2016-15-3-7-14 ◽

2016 ◽

Vol 15 (3) ◽

pp. 7-14 ◽

Cited By ~ 2

Author(s):

M. A. Koroleva ◽

I. S. Koroleva ◽

I. M. Zakroeva ◽

I. M. Gruber

Keyword(s):

Cerebrospinal Fluid ◽

Continuous Monitoring ◽

Antimicrobial Agents ◽

Meningococcal Infection ◽

Test Results ◽

Prognostic Criteria ◽

Comparison Results ◽

Moderately Resistant ◽

First Time

Relevance. One of the prognostic criteria meningococcal infection (MI) epidemic status process is the increasing number of resistant to antibiotics meningococcal strains. Aim of this study was to investigate the dynamics of invasive strains of N. meningitidis susceptibility to antibiotics in Moscow in 2006 - 2015. Materials and methods. Studied 98 strains of N. meningitidis, isolated from blood and cerebrospinal fluid of patients with MI. The study changes of sensitivity N. meningitidis to antibiotics was occured in two periods: first -2006 - 2011 and second - 2012 - 2015. The MIC was determined by E-test. Results. In the present study revealed for the first time the Russian strains of N. meningitidis, moderately resistant to penicillin (5 strains) and resistant to rifampicin (3 strains). Among the studied strains were not found resistant to ceftriaxone, ciprofloxacin, tetracycline and chloramphenicol. Discussion. Comparison results two study periods allowed to reveal the dynamics of increasing the sensitivity of N. meningitidis to antibiotics, which confirms the decline in meningococcal virulence, and as a result, continued interepidemic MI period. Conclusions. Despite the decline antibakterial resistance is required continuous monitoring.

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Prognosis criteria of the severe postembolization syndrome in patients with uterine myoma

Bulletin of Russian State Medical University ◽

10.24075/brsmu.2020.006 ◽

2020 ◽

pp. 67-74

Author(s):

E.T. Nurmukhametova ◽

M.E. Shlyapnikov

Keyword(s):

Blood Flow ◽

Uterine Myoma ◽

Microvascular Blood Flow ◽

Timely Initiation ◽

Adequate Treatment ◽

Doppler Flowmetry ◽

Occlusion Test ◽

Prognostic Criteria ◽

Flow Reserve ◽

Postembolization Syndrome

Recently specialists take an interest in organ-preserving methods of uterine fibroids treatment, one of which is uterine artery embolization (UAE). One of the method’s negative aspects is the severe postembolization syndrome (PES) development, requiring timely initiation of adequate treatment in order to avoid severe complications that could lead to the organ removal. The study was aimed to search for the prognostic criteria of the severe PES development during the preoperative period. The study included 81 UAE-treated women aged 19–50 with 7–17 week uterine myoma. The patients’ anthropometric measurements were used, as well as the skin microcirculation data obtained by laser Doppler flowmetry together with the occlusion test. Based on prognostic criteria, models with AUC (area under ROC curve) > 0.8 were presented. According to the models, the anthropometric predictors of the severe PES were the following: age under 38.5 (p < 0.05); BMI lower than 25 kg/m2 (р < 0.05), and microcirculation value (M) prior to UAE below 9.55 PU (р = 0.001). Microvascular blood flow during the occlusion test indicate that the higher the oxygen consumption index (I), intravascular resistance (Rc), capillary blood flow reserve capacity in the models, the higher the risk of the severe PES development (p < 0.05). Low alpha angle value obtained by the occlusion test (p = 0.003) as well as the UVLF value (p = 0.004) in the models also indicate the increased risk of severe PES. Multidimensional prognostic modelling admits to expect the severe PES development prior to UAE, which allows the doctor to prepare the woman for specific management and treatment.

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PROGNOSTIC CRITERIA OF RECURRENCE AND FATAL OUTCOME OF PATIENTS WITH COLORECTAL CARCINOMA

Art of Medicine ◽

10.21802/artm.2021.1.17.96. ◽

2021 ◽

pp. 96-102

Author(s):

І. І. Yakovtsova ◽

А. S. Yakimenko ◽

О. S. Protsenko ◽

І. V. Ivakhno

Keyword(s):

Colorectal Carcinoma ◽

Fatal Outcome ◽

Prognostic Criteria

Резюме. В структурі смертності від злоякісних новоутворень (ЗН) колоректальний рак (КРР) займає 2 місце після ЗН дихальної системи. Рецидивування КРР виникає в 30-40% та може характеризуватися швидкою генералізацією пухлинного процесу. Мета дослідження: пошук прогностичних критеріїв рецидивування та летального наслідку КРР за даними морфологічного дослідження оперативно видаленого матеріалу та аутопсії. Матеріали та методи. Були обрані випадки КРР ІІВ, ІІІВ стадії, Т3 за системою TNM. Сформовані групи дослідження: І – первинні КРР, що не рецидивували, ІІ – КРР з появою рецидиву впродовж 5 років та без летального наслідку (ІІА), з летальним наслідком (ІІВ). Результати обстеження. Місцеве рецидивування було в 12,5% випадків, у 82,5% рецидиви були представлені метастазами у внутрішні органи, в 5% випадків рецидиви були одночасно місцевими та з метастазами у внутрішні органи. В 70,0% рецидиви були у перші 2 роки. Виявлена статистично значуща залежність (р<0,05) між приналежністю КРР до ІІ групи дослідження та наявністю наступних критеріїв: метастазів у реґіонарних лімфатичних вузлах, васкулярної інвазії, малої відстані від краю резекції, відсутності ад’ювантної хіміотерапії, що свідчить про прогностичне значення цих факторів щодо рецидивування КРР після видалення пухлини. При дослідженні ІІ групи рецидивуючих КРР летальний наслідок від прогресії пухлиного процесу асоціювався з местастазуванням у реґіонарні лімфатичні вузли (р<0,05), відсутністю ад’ювантної хіміотерапії (р<0,05), раннім терміном появи рецидиву (р<0,03). Висновки: при дослідженні первинних КРР ІІВ, ІІІВ стадії та рівнем інвазії Т3 виявлені прогностичні критерії рецидивування та летального наслідку, що рекомендовано враховувати для індивідуалізованного підходу до лікування пацієнтів.

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