scholarly journals The Effectiveness of Applying Different Permissible Exposure Limits in Preserving the Hearing Threshold Level: A Systematic Review

2014 ◽  
Vol 56 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Balachandar S. Sayapathi ◽  
Anselm Ting Su ◽  
David Koh
Keyword(s):  
Systematic Review ◽  
Hearing Threshold ◽  
Threshold Level ◽  
Exposure Limits ◽  
Permissible Exposure Limits

Ototoxicity of trichloroethylene in concentrations relevant for the working environment

2008 ◽  
Vol 27 (3) ◽  
pp. 195-200 ◽  
Author(s):  
A Vyskocil ◽  
T Leroux ◽  
G Truchon ◽  
F Lemay ◽  
F Gagnon ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Convincing Evidence ◽  
Working Environment ◽  
Exposure Limits ◽  
Additive Interaction ◽  
Animal Data ◽  
Short Term Exposure ◽  
Adverse Effect Level ◽  
Effect Level ◽  
Permissible Exposure Limits

Organic solvents can cause hearing loss themselves or promote noise-induced hearing loss. The objective of this study was to review the literature on the effects of low-level exposure to trichloroethylene on the auditory system and consider its relevance for the occupational settings. Both human and animal investigations were evaluated only for realistic exposure concentrations based on the Quebec permissible exposure limits: 50 ppm 8-h time-weighed average exposure value (TWAEV) and 200 ppm short-term exposure value (STEV). In humans, the upper limit for considering ototoxicity data relevant to the occupational exposure situation was set at the STEV. Animal data were evaluated only for exposure concentrations up to 100 times the TWAEV. There is no convincing evidence of trichloroethylene-induced hearing losses in workers. In rats, trichloroethylene affects the auditory function mainly in the cochlear mid- to high-frequency range with a lowest observed adverse effect level (LOAEL) of 2000 ppm. No studies on ototoxic interaction after combined exposure to noise and trichloroethylene were identified in humans. In rats, supra-additive interaction was reported. Further studies with sufficient data on the trichloroethylene exposure of workers are necessary to make a definitive conclusion. In the interim, we recommend considering trichloroethylene as an ototoxic agent.

A systematic review of experimental animal studies on microbial bioaerosols: Dose-response data for the derivation of exposure limits

2019 ◽  
Vol 222 (2) ◽  
pp. 249-259 ◽  
Author(s):  
Mihai Zamfir ◽  
Doris G. Gerstner ◽  
Sandra M. Walser ◽  
Jürgen Bünger ◽  
Thomas Eikmann ◽  
...  
Keyword(s):  
Systematic Review ◽  
Experimental Animal ◽  
Dose Response ◽  
Animal Studies ◽  
Exposure Limits ◽  
Response Data

scholarly journals Sailors and the Risk of Asbestos-Related Cancer

2021 ◽  
Vol 18 (16) ◽  
pp. 8417
Author(s):  
Richard Lemen ◽  
Philip Landrigan
Keyword(s):  
Premature Death ◽  
Epidemiologic Studies ◽  
Exposure Limits ◽  
Related Disease ◽  
Occupationally Exposed ◽  
Amphibole Asbestos ◽  
Permissible Exposure Limits ◽  
Asbestos Related Disease ◽  
Risk Of Exposure ◽  
Shipyard Workers

Sailors have long been known to experience high rates of injury, disease, and premature death. Many studies have shown asbestos-related diseases among shipyard workers, but few have examined the epidemiology of asbestos-related disease and death among asbestos-exposed sailors serving on ships at sea. Chrysotile and amphibole asbestos were used extensively in ship construction for insulation, joiner bulkhead systems, pipe coverings, boilers, machinery parts, bulkhead panels, and many other uses, and asbestos-containing ships are still in service. Sailors are at high risk of exposure to shipboard asbestos, because unlike shipyard workers and other occupationally exposed groups, sailors both work and live at their worksite, making asbestos standards and permissible exposure limits (PELs). based on an 8-hour workday inadequate to protect their health elevated risks of mesothelioma and other asbestos-related cancers have been observed among sailors through epidemiologic studies. We review these studies here.

KEEPING THE OSHA PERMISSIBLE EXPOSURE LIMITS CURRENT

AIHAJ ◽  
1990 ◽  
Vol 51 (10) ◽  
pp. A-679-A-686
Author(s):  
Harry J. Ettinger
Keyword(s):  
Exposure Limits ◽  
Permissible Exposure Limits

scholarly journals Functional dysacusis: The utilization of EEG activity in the determination of hearing threshold level, a case report

1973 ◽  
Vol 20 (1) ◽  
Author(s):  
I. Hay
Keyword(s):  
Case Report ◽  
Hearing Threshold ◽  
Threshold Level ◽  
Electric Response ◽  
Test Results ◽  
Eeg Activity ◽  
Cortical Responses ◽  
The Right ◽  
Response Testing

A case of functional dysacusis was subjected to routine as well as electric response testing. Test results were unreliable and electrical cortical responses to stimuli delivered to the right ear were so poor that the results could not be utilized. A marked difference between the raw EEG tracings was observed when stimuli were switched between left to right ears. This fact was eventually used to determine the hearing threshold level of the right ear.

Tone Decay and Hearing Threshold Level in Sensorineural Loss

1971 ◽  
Vol 14 (2) ◽  
pp. 345-349
Author(s):  
Donald G. Doehring ◽  
Linda P. Swisher
Keyword(s):  
Hearing Threshold ◽  
Threshold Level ◽  
Threshold Effects ◽  
Frequency Effects ◽  
Tone Decay ◽  
Retrocochlear Pathology ◽  
Sensorineural Loss

Tone decay was assessed by the Bekesy and modified Rosenberg procedures in audiological patients with sensorineural-type loss for whom there was no neurological evidence of retrocochlear pathology. Thirty-five subjects were tested at 500 Hz, 97 at 2000 Hz, and 92 at 4000 Hz. Tone decay tended to increase with increased hearing threshold level for both tests at all three frequencies, with low but significant correlations at two of the three frequencies for each test. There were no systematic differences between the Bekesy and modified Rosenberg procedures with regard to overall level, frequency effects, or hearing threshold effects. A low but significant correlation was obtained between the two procedures at all three frequencies.

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