Hemorrhagic Events in Adult Celiac Disease Patients. Case Report and Review of the Literature

2018 ◽  
Vol 27 (1) ◽  
pp. 93-99 ◽  
Author(s):  
Alina Dima ◽  
Ciprian Jurcut ◽  
Anca Manolache ◽  
Daniel Vasile Balaban ◽  
Alina Popp ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Wide Spectrum ◽  
Case Reports ◽  
Blood Coagulation Disorders ◽  
Review Of The Literature ◽  
Diagnostic Features ◽  
Mesh Terms ◽  
Adult Celiac Disease ◽  
Hemorrhagic Events

Background & Aims: Celiac disease (CD) presents with a wide spectrum of extra-digestive symptoms, including hemorrhagic manifestations. The aim of this review was to conduct an extensive analysis of the hemorrhagic events reported in adult CD patients.Methods: Case report and review of the literature. Pubmed (MEDLINE) database search from January 1970 onwards was performed using the medical subject headings [MeSH] terms “celiac disease” AND “blood coagulation disorders”, “hemorrhage”, “hematoma”, “hematuria”, “hemoptysis”, “epistaxis”, “hemosiderosis”.Only case reports were identified on the search theme. Information on patients’ characteristics, diagnostic features, coagulation parameters, symptomatology duration, and evolution under treatment were systematically collected and summarized.Results: We present the case of a 40-year-old man hospitalized for spontaneous muscular hematomas, in whom CD was diagnosed. We performed a review of the literature and summarized the published case reports of 46 CD patients, aged between 19 and 74 years, 64% of male gender. In 25% of cases, the symptomatology was present for more than 5 years prior to CD diagnosis. The clinical hemorrhagic events were as follows: 15 patients had gastrointestinal bleeding, 9 hemoptysis, 4 epistaxis, 6 hematuria, 8 cutaneous hematoma, petechia or ecchymoses, and only in 1 case hemarthrosis, hemorrhagic vesicular dermatitis, subcortical hemorrhage, or adrenal hemorrhage. Sixty percent of the patients had digestive symptoms, while the rest had only extradigestive CD involvement. The Lane Hamilton syndrome was defined in 15 patients. The evolution under a gluten-free diet was favorable in most cases.Conclusion: This review of case reports aims to increase awareness to hemorrhagic events, rare but possible life-threatening conditions, as part of the CD clinical spectrum. To the best of our knowledge, this is the first review of all types of hemorrhagic events in adult CD patients.

scholarly journals Atypical hematological manifestation of celiac disease: A case report of aplastic anemia in a 2‐year‐old child and review of the literature

2021 ◽  
Vol 5 (2) ◽  
pp. 159-162
Author(s):  
Thea Graffenried ◽  
Mattia Rizzi ◽  
Michel Russo ◽  
Andreas Nydegger ◽  
Simon Kayemba‐Kay’s
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Aplastic Anemia ◽  
Review Of The Literature

Collagenous Sprue: A Rare, Severe Small-Bowel Malabsorptive Disorder

2011 ◽  
Vol 135 (6) ◽  
pp. 803-809
Author(s):  
Xiangrong Zhao ◽  
Rebecca L. Johnson
Keyword(s):  
Celiac Disease ◽  
Medical Literature ◽  
Case Reports ◽  
Disease Entity ◽  
Review Of The Literature ◽  
Molecular Features ◽  
Refractory Sprue ◽  
Exact Etiology ◽  
Sporadic Cases ◽  
Small Intestinal

Abstract Collagenous sprue is a severe malabsorptive disorder, histologically characterized by small intestinal villous and crypt atrophy, and a subepithelial collagen deposit, thicker than 12 µm, that entraps lamina propria cellular elements. Collagenous sprue is a rare disease entity, with only about 60 sporadic cases reported worldwide since it was first described in 1947. Its exact etiology is still under investigation, and its relationship with classic celiac disease and other refractory, spruelike intestinal disorders remains controversial. Two larger-scale studies, in 2009, brought new insights into this elusive, yet emerging, topic. Here, we present a review of the literature on the possible etiology of collagenous sprue, its proposed links to classic celiac disease and to refractory sprue, and its clinical, biochemical, histologic, and molecular features. To our knowledge, all case reports on collagenous sprue in the medical literature to date are summarized.

Primary Pyomyositis caused by Streptococcus pneumoniae in a Patient with Celiac Disease: Case Report and Review of the Literature

2016 ◽  
Vol 102 (5) ◽  
Author(s):  
Olavegogeascoechea PA ◽  
Puyo CF ◽  
Serrano Riveros P ◽  
Núñez WD ◽  
Lomban E
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Streptococcus Pneumoniae ◽  
Review Of The Literature ◽  
Disease Case

scholarly journals Celiac Disease Diagnosed in an Older Adult Patient with a Complex Neuropsychiatric Involvement: A Case Report and Review of the Literature

2020 ◽  
Vol 10 (7) ◽  
pp. 426
Author(s):  
Emma Falato ◽  
Fioravante Capone ◽  
Federico Ranieri ◽  
Lucia Florio ◽  
Marzia Corbetto ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Case Report ◽  
Older Adult ◽  
Clinical Picture ◽  
Neurological Involvement ◽  
Extraintestinal Manifestations ◽  
Review Of The Literature ◽  
History Of ◽  
Delusional Jealousy

We present a case of celiac disease (CD) diagnosis in a 75-year-old woman with a long-term history of chronic delusional jealousy and a complex neurological involvement. The case describes a very unusual clinical picture, provides some clinical clues, and highlights the importance of being aware of CD extraintestinal manifestations in order to get a timely diagnosis.

Isoniazid-Associated Psychosis: Case Report and Review of the Literature

1993 ◽  
Vol 27 (2) ◽  
pp. 167-170 ◽  
Author(s):  
Karen A. Pallone ◽  
Morton P. Goldman ◽  
Matthew A. Fuller
Keyword(s):  
Case Report ◽  
English Language ◽  
Case Reports ◽  
Data Extraction ◽  
Data Sources ◽  
Review Of The Literature ◽  
Data Synthesis ◽  
Medline Search ◽  
Study Selection ◽  
Language Literature

Objective To describe a case of isoniazid-associated psychosis and review the incidence of this adverse effect. Data Sources Information about the patient was obtained from the medical chart. A MEDLINE search of the English-language literature published from 1950 to 1992 was conducted and Index Medicus was manually searched for current information. Study Selection All case reports describing isoniazid-associated psychosis were reviewed. Data Extraction Studies were evaluated for the use of isoniazid, symptoms of psychosis, onset of symptoms, and dosage of isoniazid. Data Synthesis The case report is compared with others reported in the literature. The incidence of isoniazid-associated psychosis is rare. Conclusions The mechanism of isoniazid-associated psychosis is uncertain. It appears that isoniazid was associated with the psychosis evident in our patient and in the cases reviewed.

scholarly journals Sonographic Demonstration of Intracranial Hemorrhage in a Fetus with Hydrops Fetalis due to Rh Alloimmunization after Intrauterine Intravascular Transfusion: A Case Report and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
Rauf Melekoglu ◽  
Ebru Celik ◽  
Hasim Kural
Keyword(s):  
Case Report ◽  
Intracranial Hemorrhage ◽  
Intraventricular Hemorrhage ◽  
Case Reports ◽  
Rare Complication ◽  
Fetal Anemia ◽  
Red Cell ◽  
Review Of The Literature ◽  
Intrauterine Transfusion ◽  
Sonographic Demonstration

Intrauterine transfusion is the most common and successful intrauterine procedure for the treatment of fetal anemia due to red cell alloimmunization. Fetal intracranial hemorrhage is a very rare complication of intrauterine transfusion in patients with Rh(D) alloimmunization and it has been demonstrated only in a few case reports in the literature. Herein, we described a case of grade IV intraventricular hemorrhage that was diagnosed following the first intrauterine transfusion and reviewed the literature about the fetal intracranial hemorrhage that occurred after intrauterine intravascular transfusion procedure.

scholarly journals Embryonal tumor with abundant neuropil and true rosettes in the brainstem: case report

2015 ◽  
Vol 16 (3) ◽  
pp. 291-295 ◽  
Author(s):  
Hidetoshi Sato ◽  
Yuzo Terakawa ◽  
Naohiro Tsuyuguchi ◽  
Yuko Kuwae ◽  
Masahiko Ohsawa ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Case Reports ◽  
Subtotal Resection ◽  
Surgical Removal ◽  
Rare Entity ◽  
Review Of The Literature ◽  
Embryonal Tumor

Embryonal tumor with abundant neuropil and true rosettes (ETANTR) is rarely seen in the brainstem, and there are few case reports of brainstem ETANTR in the literature. Accordingly, the characteristics and the role of surgical treatment of this rare entity remain unclear. The authors present a case of brainstem ETANTR involving a 33-month-old boy along with a review of the literature and discuss the role of surgical removal in the treatment of this entity. In the authors’ case, the tumor was surgically treated with subtotal resection, which resulted in improvement of the patient’s preoperative symptoms. Chemotherapy was initiated but did not appear to be effective, radiotherapy was declined, and the boy died 6 months after the operation. Based on their analysis of 10 previously reported cases and their own case, the authors conclude that, with respect to survival, surgery may be beneficial even in cases of ETANTR in the brainstem. They note, however, that further studies with a large number of cases are needed to validate the role of surgical treatment in brainstem ETANTR.

scholarly journals Solitary fibrous tumors of the spine: a pediatric case report with a comprehensive review of the literature

2017 ◽  
Vol 19 (3) ◽  
pp. 339-348 ◽  
Author(s):  
Gregory W. Albert ◽  
Murat Gokden
Keyword(s):  
Case Report ◽  
Case Reports ◽  
Case Series ◽  
Review Of The Literature ◽  
Benign Lesions ◽  
Pediatric Case ◽  
Comprehensive Review ◽  
Solitary Fibrous Tumors ◽  
Small Case Series

Solitary fibrous tumors of the spine are rare lesions. Their description in the literature is limited to case reports and small case series. While generally benign lesions, they can recur and occasionally occur as malignancies. Here the authors present the case of a 10-year-old boy, the youngest patient and first preadolescent reported thus far, with this condition. In addition, they perform a comprehensive review of all previously published cases of spinal solitary fibrous tumors.

scholarly journals A Case Report of Urinary Bladder Carcinosarcoma and Review of the Literature

2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
Christos Zachariadis ◽  
Ioannis Efthimiou ◽  
Stylianos Giannakopoulos ◽  
Athanasios Bantis ◽  
Alexandra Giatromanolaki ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Urinary Bladder ◽  
Treatment Option ◽  
Transurethral Resection ◽  
Case Reports ◽  
Review Of The Literature ◽  
Small Series ◽  
Radiotherapy Alone ◽  
Aggressive Tumors

Carcinosarcoma of the bladder is an unusual tumour characterized by a combination of malignant epithelial and soft tissue elements. Most of the reported cases have been case reports or small series. Optimal treatment is uncertain. We herein report our experience in such a case treated with transurethral resection followed by radiotherapy with adverse final outcome. Treatment of bladder carcinosarcomas should be aggressive and multimodal but optional treatment is still unknown. Radiotherapy alone is insufficient as a treatment option of these aggressive tumors.

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