Self Organized Skin Equivalent by Epithelial and Fibroblast Cells on Polycaprolactone Electrospun Mat with Porous Fibers

Collagen-functionalized electrospun smooth and porous poly(l-lactide) scaffolds supporting keratinocytes and fibroblasts as a potential model to serve as self-organized skin substitute.

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Problem behavior in autism spectrum disorders: A paradigmatic self-organized perspective of network structures

Behavioral and Brain Sciences ◽

10.1017/s0140525x18001188 ◽

2019 ◽

Vol 42 ◽

Author(s):

Lucio Tonello ◽

Luca Giacobbi ◽

Alberto Pettenon ◽

Alessandro Scuotto ◽

Massimo Cocchi ◽

...

Keyword(s):

Autism Spectrum Disorder ◽

Problem Behaviors ◽

Autism Spectrum ◽

The Self ◽

Network Structures ◽

Self Organized ◽

Critical Equilibrium ◽

Self Organized Criticality ◽

Acute Agitation ◽

Spectrum Disorders

AbstractAutism spectrum disorder (ASD) subjects can present temporary behaviors of acute agitation and aggressiveness, named problem behaviors. They have been shown to be consistent with the self-organized criticality (SOC), a model wherein occasionally occurring “catastrophic events” are necessary in order to maintain a self-organized “critical equilibrium.” The SOC can represent the psychopathology network structures and additionally suggests that they can be considered as self-organized systems.

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Desmosomal distribution in the epidermis of a non-contracting human skin equivalent

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100124884 ◽

1992 ◽

Vol 50 (1) ◽

pp. 896-897

Author(s):

L.X. Oakford ◽

S.D. Dimitrijevich ◽

R. Gracy

Keyword(s):

Human Skin ◽

Basal Layer ◽

Skin Equivalent ◽

Tissue Component ◽

Intact Skin ◽

Similar Sequence ◽

Sequence Of Events ◽

Suprabasal Keratinocytes ◽

Human Skin Equivalent

In intact skin the epidermal layer is a dynamic tissue component which is maintained by a basal layer of mitotically active cells. The protective upper epidermis, the stratum corneum, is generated by differentiation of the suprabasal keratinocytes which eventually desquamate as anuclear comeocytes. A similar sequence of events is observed in vitro in the non-contracting human skin equivalent (HSE) which was developed in this lab (1). As a part of the definition process for this model of living skin we are examining its ultrastructural features. Since desmosomes are important in maintaining cell-cell interactions in stratified epithelia their distribution in HSE was examined.

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Dynamics of Self-Organized and Self-Assembled Structures

10.1017/cbo9780511609725 ◽

2009 ◽

Cited By ~ 100

Author(s):

Rashmi C. Desai ◽

Raymond Kapral

Keyword(s):

Self Organized ◽

Self Assembled

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Transformative Encounters and Uncanny Intimacies: Biotechnology and Contemporary Art – A Practitioner's Approach and Perspective

Somatechnics ◽

10.3366/soma.2012.0061 ◽

2012 ◽

Vol 2 (2) ◽

pp. 263-283 ◽

Cited By ~ 1

Author(s):

Svenja J. Kratz

Keyword(s):

Tissue Culture ◽

Human Skin ◽

Contemporary Art ◽

Skin Equivalent ◽

Biomedical Innovation ◽

Equivalent Models ◽

Science Projects ◽

Insight Into ◽

Human Skin Equivalent

Abstract: Presented from an ArtScience practitioner's perspective, this paper provides an overview of Svenja Kratz's experience working as an artist within the area of cell and tissue culture at QUT's Institute of Health and Biomedical Innovation (IHBI). Using The Absence of Alice, a multi-medium exhibition based on the experience of culturing cells, as a case study, the paper gives insight into the artist's approach to working across art and science and how ideas, processes, and languages from each discipline can intermesh and extend the possibilities of each system. The paper also provides an overview of her most recent artwork, The Human Skin Equivalent/Experience Project, which involves the creation of personal jewellery items incorporating human skin equivalent models grown from the artist's skin and participant cells. Referencing this project, and other contemporary bioart works, the value of ArtScience is discussed, focusing in particular on the way in which cross-art-science projects enable an alternative voice to enter into scientific dialogues and have the potential to yield outcomes valuable to both disciplines.

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