For backward status of a missile guidance device monitoring methods, developed a set of ground monitoring system based on virtual instrument technology. The system meets the standard test of a certain type of missile guidance device, the data acquisition card and controller of PXI bus as the hardware platform, using LabVIEW as the software development platform, The acquisition of analog signal, video signal and serial communication set in one, it can detect the performance and parameters of the guidance device, and monitoring the flight trajectory of the missile qualitatively. The application results show that the monitoring system is stable and reliable, improve the efficiency and accuracy of monitoring, and has a certain popularization value.