ID:2030 Malnutrition and Quality of Life in Patients with Non-Small-Cell Lung Cancer at Thai Nguyen Cancer center

Nowadays Progressive weight loss, common reduces performance and quality of life in patients with advanced lung cancer. However, there is a paucity of studies that focus on nutritional status and quality of life of non-small cell lung cancer (NSCLC) patients. The present study seeks to determine the nutritional status, and its relation to quality of life, of NSCLC patients. One hundred NSCLC patients (mean age 60,1 years) were evaluated during therapy at the Lower Silesian Center of Lung Diseases in Thai Nguyen – Vietnam. Nutritional status was evaluated by means of the Mini-Nutritional Assessment (MNA) and quality of life by means of two instruments developed by the European Organization for the Research and Treatment of Cancer (EORTC): QLQ-C30 and QLQ-LC13 questionnaires. The MNA revealed that up to 49,1% of patients were undernourished, 24,9% were at risk of malnutrition, and only 26.0% showed a normal nutrition. The well-nourished respondents evaluated their quality of life better in all functional scaQLQ-C30 and specific LC13 questionnaires. In univariate analysis, malnutrition significantly correlated with decreased quality of life and the intensity of symptoms in both questionnaires. In multivariate analysis, malnutrition was an independent determinant of decreased quality of life in physical functioning domain (β ¼ 0.015; p < 0.001). We conclude that malnutrition has an impact on quality of life and on the presentation of symptoms in NSCLC patients. Therefore, nutritional care should be integrated into the global oncology as an adjunct to symptomatic treatment. les (33.3 vs. 41.7 vs. 66.7, respectively) and presented less intensive symptoms in general, research has contributed to the current viewpoint cancer treatment.

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Efficacy of nivolumab (Nivo) as 2+ line treatment and quality of life (QoL) in advanced refractory non-small cell lung cancer (NSCLC) patients: Interim results of observational prospective study.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.15_suppl.e21126 ◽

2018 ◽

Vol 36 (15_suppl) ◽

pp. e21126-e21126

Author(s):

Konstantin K. Laktionov ◽

Alla L. Arzumanyan ◽

Larisa Bolotina ◽

Valeriy Vladimirovich Breder ◽

Natalia N. Buevich ◽

...

Keyword(s):

Quality Of Life ◽

Lung Cancer ◽

Prospective Study ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Line Treatment ◽

Small Cell Lung ◽

Nsclc Patients

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Symptom response in non-small cell lung cancer (NSCLC) patients (pts) treated with erlotinib: Quality of life analysis of the NCIC CTG BR.21 trial

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.7018 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 7018-7018 ◽

Cited By ~ 7

Author(s):

A. Bezjak ◽

F. Shepherd ◽

D. Tu ◽

G. Clark ◽

P. Santabarbara ◽

...

Keyword(s):

Quality Of Life ◽

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Small Cell ◽

Small Cell Lung ◽

Symptom Response ◽

Life Analysis ◽

Nsclc Patients

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The experience of weight loss and its associated burden in patients with non-small cell lung cancer: results of an online survey

JCSM Clinical Reports ◽

10.17987/jcsm-cr.v2i2.18 ◽

2017 ◽

Vol 2 (2) ◽

Cited By ~ 1

Author(s):

Ana Maria Rodriguez ◽

Julia Braverman ◽

Dimple Aggarwal ◽

John Friend ◽

Elizabeth Duus

Keyword(s):

Quality Of Life ◽

Lung Cancer ◽

Weight Loss ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Online Survey ◽

Small Cell ◽

Small Cell Lung ◽

Nsclc Patients

Background: The main objectives of this study were to characterize and compare the burden of non-small cell lung cancer (NSCLC) patients reporting considerable unintentional weight loss (≥ 5% in the past 6 months or ≥ 2% for a BMI < 20 kg/m2) to those who did not.Methods: Ninety-five advanced NSCLC patients were surveyed from the online patient-powered community PatientsLikeMe, which included health-related quality of life (QLQ-C15-PAL), anorexia-cachexia symptoms/concerns (FAACT A/CS domain), distress levels, clinical/demographic characteristics, and impact of weight loss (open-ended questions).Results: Thirty-five patients (37%) had considerable weight loss at the time of the survey and 60 (63%) did not. Mean age was 59 years, and most were female (81%) and American (81%). Patients with weight loss reported significantly (p < 0.05) lower overall quality of life (55.2 vs. 66.9), worsened anorexia-cachexia symptoms/concerns (30.7 vs. 36.0), and higher symptomology, specifically fatigue (64.8 vs. 49.1), nausea (19.5 vs. 9.2), and appetite loss (41.0 vs. 23.9) – than patients without weight loss. In addition, significantly more patients who lost weight reported moderate/high distress levels than patients who did not (71% vs. 38%). For patients with weight loss, changes in food taste, fatigue, and decrease in appetite were the most frequently reported symptoms with the greatest impact on their lives, and main worries included loss of energy and disease progression.Conclusions: Weight loss represents a substantial problem for NSCLC patients and symptoms associated with weight loss significantly impact patient lives. Interventions targeted at maintaining/increasing body weight may help to alleviate these findings.

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