Differential Influence of Family History of Hypertension and Premature Myocardial Infarction on Systolic Blood Pressure and Left Ventricular Mass Trajectories in Youth

PEDIATRICS ◽  
2003 ◽  
Vol 111 (6) ◽  
pp. 1387-1393 ◽  
Author(s):  
J. C. Dekkers ◽  
F. A. Treiber ◽  
G. Kapuku ◽  
H. Snieder
Keyword(s):  
Myocardial Infarction ◽  
Blood Pressure ◽  
Family History ◽  
Systolic Blood Pressure ◽  
Left Ventricular Mass ◽  
Left Ventricular ◽  
Ventricular Mass ◽  
History Of ◽  
Premature Myocardial Infarction ◽  
Family History Of Hypertension

Influence of Family History of Hypertension on the Relationships between Blood Pressure, Body Weight, Electrolyte Metabolism, Renin, Prolactin and Parathormone

1981 ◽  
Vol 61 (s7) ◽  
pp. 359s-362s ◽  
Author(s):  
F. Wessels ◽  
D. Hoffmann ◽  
H. Wagner ◽  
H. Zumkley
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Family History ◽  
Plasma Renin Activity ◽  
Systolic Blood Pressure ◽  
Plasma Renin ◽  
Renin Activity ◽  
Creatinine Ratio ◽  
History Of ◽  
Family History Of Hypertension

1. The influence of family history of hypertension on the relationships between blood pressure, relative body weight, sodium/creatinine ratio of the 24 h urine, plasma renin activity and the plasma concentration of prolactin and parathormone were examined in 102 healthy male students. 2. Grouping together results from all students showed significant positive correlations between systolic blood pressure and prolactin, parathormone as well as relative body weight, between plasma renin activity and prolactin and a significant negative correlation between plasma renin activity and sodium/creatinine ratio of the 24 h urine. 3. By dividing the students into two groups according to their family history of hypertension we could demonstrate in those with family history of hypertension a highly significant positive correlation between mean blood pressure and sodium/creatinine ratio of the 24 h urine and an improvement of the correlations between systolic blood pressure and prolactin and between sodium/creatinine ratio of the 24 h urine and plasma renin activity. In students without family history of hypertension these relationships were no longer detectable. In the students without family history of hypertension the correlations between systolic blood pressure and relative body weight as well as between plasma renin activity and prolactin gained substantially in significance. In students with positive family history of hypertension these correlations could no longer be demonstrated. The correlations between systolic blood pressure and parathormone remained unaffected by family history of hypertension. 4. The results suggest that a genetic predisposition to essential hypertension is able to intensify the blood pressure effect of Na intake and of prolactin, which, besides its function as a sex hormone, is presumed additionally to be able to retain salt. However, the positive relationship between body weight and blood pressure, as well as between plasma renin activity and prolactin, the significance of which increases greatly in subjects without family history of hypertension, appears to be lost as the result of the increased sensitivity to salt in positive family history of hypertension.

scholarly journals Regular Cocaine Use Is Associated with Increased Systolic Blood Pressure, Aortic Stiffness and Left Ventricular Mass in Young Otherwise Healthy Individuals

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e89710 ◽  
Author(s):  
Rebecca Kozor ◽  
Stuart M. Grieve ◽  
Stefan Buchholz ◽  
Sharlene Kaye ◽  
Shane Darke ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Left Ventricular Mass ◽  
Aortic Stiffness ◽  
Left Ventricular ◽  
Healthy Individuals ◽  
Cocaine Use ◽  
Ventricular Mass
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