scholarly journals Peanut Gastrointestinal Delivery Oral Immunotherapy in Adolescents: Results of the Build–up Phase of a Randomized, Double–Blind, Placebo-Controlled Trial (PITA Study)

PEDIATRICS ◽  
2019 ◽  
Vol 144 (Supplement 1) ◽  
pp. S33-S34
Author(s):  
Mary V. Lasley
Keyword(s):  
Controlled Trial ◽  
Oral Immunotherapy ◽  
Double Blind ◽  
Double Blind Placebo

Double-Blind, Placebo-Controlled Trial of Oral Immunotherapy (OIT) in Peanut (PN) Allergic Children: A Follow-up

2010 ◽  
Vol 125 (2) ◽  
pp. AB58 ◽  
Author(s):  
S.M. Jones ◽  
A.M. Scurlock ◽  
L. Pons ◽  
T.T. Perry ◽  
A.R. Morgan ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Oral Immunotherapy ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Impact of Peanut Allergy on Quality of Life: Baseline Results from PALISADE, a Phase 3, Double-Blind, Placebo-Controlled Trial for AR101 Oral Immunotherapy

2019 ◽  
Vol 143 (2) ◽  
pp. AB155
Author(s):  
Julie Wang ◽  
Douglas T. Johnston ◽  
Jay A. Lieberman ◽  
Christine Birchwood ◽  
Sarah Acaster ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Peanut Allergy ◽  
Controlled Trial ◽  
Oral Immunotherapy ◽  
Phase 3 ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Daniel R. Monaco ◽  
Brandon M. Sie ◽  
Thomas R. Nirschl ◽  
Audrey C. Knight ◽  
Hugh A. Sampson ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Oral Immunotherapy ◽  
Phage Library ◽  
Allergic Reactions ◽  
Wheat Allergy ◽  
Display System ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Allergenic Proteins ◽  
Antibody Specificities

AbstractAllergic reactions occur when IgE molecules become crosslinked by antigens such as food proteins. Here we create the ‘AllerScan’ programmable phage display system to characterize the binding specificities of anti-allergen IgG and IgE antibodies in serum against thousands of allergenic proteins from hundreds of organisms at peptide resolution. Using AllerScan, we identify robust anti-wheat IgE reactivities in wheat allergic individuals but not in wheat-sensitized individuals. Meanwhile, a key wheat epitope in alpha purothionin elicits dominant IgE responses among allergic patients, and frequent IgG responses among sensitized and non-allergic patients. A double-blind, placebo-controlled trial shows that alpha purothionin reactivity, among others, is strongly modulated by oral immunotherapy in tolerized individuals. AllerScan may thus serve as a high-throughput platform for unbiased analysis of anti-allergen antibody specificities.

Peanut gastrointestinal delivery oral immunotherapy in adolescents: Results of the build-up phase of a randomized, double-blind, placebo-controlled trial (PITA study)

2018 ◽  
Vol 48 (7) ◽  
pp. 862-874 ◽  
Author(s):  
J.-L. Fauquert ◽  
E. Michaud ◽  
B. Pereira ◽  
L. Bernard ◽  
N. Gourdon-Dubois ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Oral Immunotherapy ◽  
Double Blind ◽  
Double Blind Placebo

Clinical efficacy of specific immunotherapy to cat dander: a double-blind placebo-controlled trial

1997 ◽  
Vol 27 (8) ◽  
pp. 860-867 ◽  
Author(s):  
V.A. VARNEY ◽  
J. EDWARDS ◽  
K. TABBAH ◽  
H. BREWSTER ◽  
G. MAVROLEON ◽  
...  
Keyword(s):  
Clinical Efficacy ◽  
Specific Immunotherapy ◽  
Controlled Trial ◽  
Double Blind ◽  
Double Blind Placebo

A randomized double blind, placebo controlled trial of a Chinese herbal preparation (CH100) in chronic Hepatitis C

2001 ◽  
Vol 120 (5) ◽  
pp. A384-A384
Author(s):  
L MOLLISON ◽  
L TOTTEN ◽  
C HOVELL ◽  
K THAYNE ◽  
C CONNELLY ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Controlled Trial ◽  
Herbal Preparation ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Chinese Herbal
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