Children Exposed to Maltreatment: Assessment and the Role of Psychotropic Medication

SynopsisElevation of serum creatine kinase (CK) concentrations occurs almost invariably in neuroleptic malignant syndrome (NMS). However, the role of CK levels in the diagnosis of the syndrome remains controversial. This study measured CK levels in patients who became pyrexial while on psychotropic medication and thereby mimicked some of the features of NMS. In all of these cases a diagnosis of infectious illness was made and patients responded to appropriate antibiotic therapy without alteration in psychotropic medication. Two other groups were studied for comparison – patients on psychotropics who were apyrexial and patients who became pyrexial but were not on psychotropics. Significant, unexpected elevations of CK were documented in 70% of those patients who became pyrexial while on psychotropics – in three cases elevation of concentrations to more than 1000 IU/1 (ten times reference value) were found. Thirty per cent of patients who became pyrexial but were not on psychotropics also developed elevation of CK but this was of a much smaller magnitude (lt; 200 IU/1 in five out of six cases). The results of the study suggest that elevation of CK is a non-specific finding, particularly in patients who become pyrexial on psychotropics. Use of CK as a diagnostic criterion may lead to overdiagnosis of NMS.

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Gender and psychotropic medication use: The role of intimate partner violence

Preventive Medicine ◽

10.1016/j.ypmed.2007.07.019 ◽

2008 ◽

Vol 46 (6) ◽

pp. 615-621 ◽

Cited By ~ 17

Author(s):

Sarah E. Romans ◽

Marsha M. Cohen ◽

Tonia Forte ◽

Janice Du Mont ◽

Ilene Hyman

Keyword(s):

Intimate Partner Violence ◽

Psychotropic Medication ◽

Partner Violence ◽

Medication Use ◽

Intimate Partner

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Clinical Guidelines for Management of Patients under Lieutenant Governor's Warrants

The Canadian Journal of Psychiatry ◽

10.1177/070674378603100909 ◽

1986 ◽

Vol 31 (9) ◽

pp. 838-842 ◽

Cited By ~ 1

Author(s):

Syed Naveed Akhtar

Keyword(s):

Psychotropic Medication ◽

Clinical Guidelines ◽

Legal Issues ◽

Free Trial ◽

Post Trial ◽

Drug Free ◽

Legal Judgement

This paper examines three categories of mentally abnormal offenders who are held under Lieutenant Governor's Warrants. It explores the psychiatric-legal issues in cases of pre-trial (not fit to stand trial) and post-trial (not guilty by reason of insanity) L. G. W.'s. An attempt is made to provide a structure for such psychiatric-legal evaluations. Clinical guidelines are offered about the objectives, the assumptions and the criteria which form the basis of such evaluations. Suggestions are made for collection of relevant data which should inform psychiatric and legal judgement-making in this area. The role of the psychotropic medication in N.G.I. cases is discussed. It is recommended that whenever medically feasible, a controlled drug-free trial should be carried out in N. G.I. cases prior to their final release, in order to unambiguously establish their need for medication.

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Psychotropic Medication Use during Pregnancy and Lactation: Role of Ultrasound Assessment

Donald School Journal of Ultrasound in Obstetrics & Gynecology ◽

10.5005/jp-journals-10009-1345 ◽

2014 ◽

Vol 8 (1) ◽

pp. 109-121 ◽

Cited By ~ 1

Author(s):

Ritsuko Pooh ◽

Andrew Matthys ◽

Maria Teresa Ambat

Keyword(s):

Psychotropic Medication ◽

Obstet Gynecol ◽

Case Reports ◽

Medication Use ◽

Review Article ◽

Ultrasound Images ◽

Teratogenic Effects ◽

Pregnancy And Lactation ◽

Ultrasound Assessment

ABSTRACT The potential teratogenic effects of psychotropic medication use during pregnancy have been scrutinized ever since thalidomide contributed to phocomelia in the 1950's. Up to 35% of the half a million women becoming pregnant each day take psychotropic medication(s). Teratogens alter normal intrauterine fetal growth, anatomic structures, functioning and postnatal development. In this educational review article, we examine whether different classes of psychotropic medications have the potential to be teratogens or have other nonteratogenic effects. Specifically, we examined antidepressants (SSRIs, TCAs), anticonvulsants (valproate, carbamazepime, lamotrigine), antipsychotics, Benadryl and Lithium. We also provided case reports with ultrasound images as well as a review quiz. How to cite this article Matthys A, Ambat MT, Pooh R, Kupesic Plavsic S. Psychotropic Medication Use during Pregnancy and Lactation: Role of Ultrasound Assessment. Donald School J Ultrasound Obstet Gynecol 2014;8(1):109-121.

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