Case Reports Are Valuable

PEDIATRICS ◽  
1977 ◽  
Vol 60 (5) ◽  
pp. 762-762
Author(s):  
Edward B. Shaw

The excellent case report "Mucocutaneous Lymph Node Syndrome (MLNS) in the Continental United States" by Goldsmith et al. (Pediatrics 57:431, March 1976) is an example of the importance of the report of a single case. This should alert others to this syndrome in their own practices. I am reminded of a note by Roger Lee1 in 1952: "Are three cases enough to make a series? Parenthetically I have a fondness for the carefully reported single case, which in the days before mass production was a feature of a medical journal .... a series of three cases leads to statistical atrocities and aberrations and deductions."

PEDIATRICS ◽  
1976 ◽  
Vol 57 (3) ◽  
pp. 431-435
Author(s):  
Richard W. Goldsmith ◽  
Donald Gribetz ◽  
Lotte Strauss

This report details a case of mucocutaneous lymph node syndrome (MLNS) recognized in the continental United States. Reported originally by Kawasaki in 1967,1 the syndrome has since occurred widely in Japan.2 Except for Melish et al.'s report of nine cases in Hawaii, MLNS has thus far not been reported from any other area.3 CASE REPORT T. S., a 2-year-old white boy, became ill with fever on August 19, 1974, and was examined on the third day of illness. His temperature had fluctuated between 38.9 and 39.4 C; when examined he had a markedly tender 2 x 4-cm single anterior cervical node accompanied by redness of the overlying skin.


1976 ◽  
Vol 88 (1) ◽  
pp. 81-83 ◽  
Author(s):  
James S. Brown ◽  
Gerard J. Billmeier ◽  
Frederick Cox ◽  
Mazen Ibrahim ◽  
William P. Stepp ◽  
...  

PEDIATRICS ◽  
1975 ◽  
Vol 56 (5) ◽  
pp. 839-839
Author(s):  
Barbara W. Stechenberg ◽  
James P. Keating

In the September 1974 issue of Pediatrics, Kawasaki et al.1 described the clinical manifestations of acute febrile mucocutaneous lymph node syndrome (MLNS), and Yanagisawa et al.2 described a patient with MLNS who died of aneurysmal dilatation and bilateral obstruction of the coronary arteries. In an editorial in the same issue, Fetterman and Hashida3 suggested that the syndrome had not been recognized in the continental United States. Such a case may have been described but not recognized as a case of MLNS.


PEDIATRICS ◽  
1978 ◽  
Vol 61 (4) ◽  
pp. 670-670
Author(s):  
David M. Morens ◽  
David B. Nelson

In a letter to the editor in the July 1977 issue of Pediatrics (60:133), Drs. John and Wilson drew attention to the geographic prevalence of Kawasaki disease (mucocutaneous lymph node syndrome). Kawasaki disease has been reported not only from Japan, Korea, Canada, Greece, Hawaii, and the continental United States, but also Australia,1 Belgium,2 the Netherlands,3 Italy,4 West Germany,5 Sweden,6 England,7 Scotland,8 and Turkey,9 as well as Spain, Mexico, Taiwan province, and the Philippines (Center for Disease Control [CDC], unpublished data).


1978 ◽  
Vol 42 (7) ◽  
pp. 901-909 ◽  
Author(s):  
YUTAKA KONISHI ◽  
NORIKAZU TATSUTA ◽  
SHIGEHITO MIKI ◽  
YUKIO CHIBA ◽  
CHlN-TZER KAO ◽  
...  

1980 ◽  
Vol 2 (4) ◽  
pp. 107-114
Author(s):  
Marian E. Melish

Kawasaki syndrome or the mucocutaneous lymph node syndrome (MCLS, MLNS) is an acute febrile exanthematous illness of children, first recognized in Japan by Kawasaki in 1967.1 In 1970, the Research Committee of MCLS, supported by the Ministry of Health and Welfare of the Japanese government, organized a case registry to elucidate the clinical, pathologic, epidemiologic, and etiologic features. By 1974, the committee had collected approximately 5,000 cases from all over Japan.1,2 The illness has continued to be recognized in Japan with more than 10,000 cases registered by 1979. The disease was recognized independently in the United States by Melish et al with 12 cases encountered between 1971 and 1974.3,4 Although these American workers had no knowledge of the Japanese experience they independently identified the same diagnostic criteria. Later consultations with Japanese MCLS researchers have established that the cases in Hawaii and the cases in Japan were indistinguishable in their presenting manifestations and their clinical course. Since 1974, Kawasaki syndrome has been recognized worldwide. Outside Japan, the illness appears to be most prevalent in Hawaii which has the largest published series3; the largest proportion of cases in the United States reported to the Center for Disease Control come from this state. The experience at the Kapiolani-Children's Medical Center now includes more than 100 cases from various parts of Hawaii.


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