scholarly journals Mouth Preparation Pada Anak Dengan Kelainan Jantung Kongenital Tetralogi of Fallot, Pre-operatif Kardiovaskuler

2007 ◽  
Vol 6 (2) ◽  
pp. 85
Author(s):  
Muhammad Harun Achmad ◽  
Maryanne Susanti

Teeth dimension is the factor influenced the incidence of toothimpaction. The most The congenital figure of the heart defect incidentin several educational hospitals in Indonesia almost reached 9 per1,000 born babies who survive to live (0.8-1.2%). Tetralogi of Fallotwas one of the cyanotic congenital heart defects that were often foundto children. This situation had four forms of the deviation: defect of theventricle septum, overriding aorta, stenosis infundibuler, andhypertrophy of the right ventricle. As in the case of other congenitalheart defect, in Tetralogi Fallot often happened fatal complication suchas endocarditis bacterialis that had tight relationship to the infection inteeth. In dentistry, the treatment for children with cardiovasculardisease needs holistic handling to prevent the occurrence endocarditisbacterialis. This paper discussed the teeth and the mouth conditionsas well as the therapy in two cases of the child with tetralogi of Fallot.Two female patients came to the Special Dental Care clinic, RSHSBandung with the congenital Tetralogi of Fallot heart defect to undergomouth preparation prior to the heart operation in Jakarta. Theconclusion is as in the case of the congenital heart other defectcyanotic, in Tetralogi Fallot fatal complications such as endocarditisbacterialis could happen. Endocarditis bacterialis was caused by the '':bacterial infection in the heart valve or endocardium.

Author(s):  
Relin Vliet ◽  
Lucia J. M. Kroft ◽  
Mark G. Hazekamp ◽  
Arno A. W. Roest ◽  
Roel L. F. Palen

1989 ◽  
Vol 117 (4) ◽  
pp. 957-959 ◽  
Author(s):  
Patrick Hallali ◽  
Bernard Iung ◽  
Alain Davido ◽  
Jean-Paul Binet ◽  
Henri Leriche ◽  
...  

2017 ◽  
Vol 113 (12) ◽  
pp. 1509-1520 ◽  
Author(s):  
Odilia I. Woudstra ◽  
Suchit Ahuja ◽  
Jouke P. Bokma ◽  
Berto J. Bouma ◽  
Barbara J.M. Mulder ◽  
...  

2019 ◽  
Vol 49 (2) ◽  
pp. 638-647
Author(s):  
Amalie Bøggild Schmidt ◽  
Marie Lund ◽  
Giulia Corn ◽  
Nina Øyen ◽  
Jan Wohlfahrt ◽  
...  

Abstract Background Pre-pregnancy diabetes is a strong risk factor for congenital heart defects (CHDs), suggesting a role for glucose in the causal pathway. Oral corticosteroids may cause hyperglycemia and maternal use could affect embryonic heart development. The objective of this study was to determine the association between maternal intake of oral corticosteroids 0–8 weeks after conception and CHDs in offspring. Methods A register-based nationwide prevalence study including all live singleton births in Denmark, 1996–2016, was conducted. In total, 1 194 687 individuals and their mothers were identified and linked with information on offspring CHDs and the mothers’ use of oral corticosteroids in early pregnancy. Corticosteroid use was defined as a filled prescription for maternal use of oral corticosteroid 0–8 weeks after conception. CHDs were identified through International Classification of Diseases codes. The association was estimated by prevalence (odds) ratios using logistic regression and propensity score-matched analyses. Results Among 1 194 687 live births, 2032 had a mother who had used oral corticosteroids 0–8 weeks from conception. Of these offspring, 32 had a heart defect. Among the offspring of never-users of oral corticosteroids, 10 534 had a heart defect. The adjusted prevalence ratio was 1.29 (95% confidence interval, 0.90–1.84) comparing offspring prevalence of heart defects in oral corticosteroid users with that in oral corticosteroid never-users. Propensity score-matched analysis yielded similar results (prevalence ratio 1.38; 95% confidence interval, 0.95–2.02). Conclusions This study supports that there is no association between maternal use of oral corticosteroids in the first 8 weeks after conception and CHDs.


Author(s):  
Yunping Lei ◽  
Katherine L Ludorf ◽  
Xiao Yu ◽  
Renata H Benjamin ◽  
Xue Gu ◽  
...  

Abstract BACKGROUND Maternal hypertension has been associated with congenital heart defect occurrence in several studies. We assessed whether maternal genotypes associated with this condition were also associated with congenital heart defect occurrence. METHODS We used data from the National Birth Defects Prevention Study to identify non-Hispanic white (NHW) and Hispanic women with (cases) and without (controls) a pregnancy in which a select simple, isolated heart defect was present between 1999 and 2011. We genotyped 29 hypertension-related single nucleotide polymorphisms (SNPs). We conducted logistic regression analyses separately by race/ethnicity to assess the relationship between the presence of any congenital heart defect and each SNP and an overall blood pressure genetic risk score (GRS). All analyses were then repeated to assess 4 separate congenital heart defect subtypes. RESULTS Four hypertension-related variants were associated with congenital heart defects among NHW women (N = 1,568 with affected pregnancies). For example, 1 intronic variant in ARHGAP2, rs633185, was associated with conotruncal defects (odds ratio [OR]: 1.3, 95% confidence interval [CI]: 1.1–1.6). Additionally, 2 variants were associated with congenital heart defects among Hispanic women (N = 489 with affected pregnancies). The GRS had a significant association with septal defects (OR: 2.1, 95% CI: 1.2–3.5) among NHW women. CONCLUSIONS We replicated a previously reported association between rs633185 and conotruncal defects. Although additional hypertension-related SNPs were also associated with congenital heart defects, more work is needed to better understand the relationship between genetic risk for maternal hypertension and congenital heart defects occurrence.


2021 ◽  
Vol 9 ◽  
Author(s):  
Sara Hirani Lau-Jensen ◽  
Benjamin Asschenfeldt ◽  
Lars Evald ◽  
Vibeke E. Hjortdal

Background: Patients with congenital heart defects have a well-established risk of neuropsychiatric comorbidities. Inattention and hyperactivity are three to four times more frequent in children with complex congenital heart defects. We have previously shown a higher burden of overall attention deficit/hyperactivity disorder (ADHD) symptoms in adults with simple congenital heart defects as well. However, it is unknown whether the higher burden of ADHD symptoms is mainly driven by hyperactivity, inattention, or both.Methods: The participants [simple congenital heart defect = 80 (26.6 years old), controls = 36 (25.3 years old)] and a close relative for each (n = 107) responded to the long version of the Conners' Adults ADHD Rating Scales questionnaire. Our primary and secondary outcomes are mean T-scores in the ADHD scores and symptom sub-scores.Results: Patients with simple congenital heart defects reported a higher mean T-score at all three DSM-IV ADHD scores (ADHD—combined: 52.8 vs. 44.9, p = 0.007, ADHD—inattention: 55.5 vs. 46.4, p = 0.002, and ADHD—hyperactivity: 49.4 vs. 44.0, p = 0.03) and in all four ADHD symptom sub-scores (inattention/memory problems: 50.3 vs. 44.2, p = 0.001, hyperactivity/restlessness: 49.7 vs. 45.9, p = 0.03, impulsivity/emotional lability: 50.0 vs. 41.3, p = 0.001, and self-esteem problems: 53.8 vs. 46.3, p = 0.003). The results were maintained after the removal of outliers (incongruent responses), albeit the hyperactivity/restlessness ADHD symptom sub-score lost significance. Self- and informant ratings differed significantly on the ADHD—inattention score for the congenital heart defect group, where informants rated the ADHD—inattention scores better than the congenital heart defect patients rated themselves.Conclusions: Patients with a simple congenital heart defect have a higher symptom burden across all ADHD scores and all symptom sub-scores. The higher burden of ADHD is driven by both inattention and hyperactivity symptoms, though the inattention symptoms seem more prominent. Close relatives were less aware of the inattention symptoms than the congenital heart defect patients themselves. Routine screening for ADHD symptoms may be warranted to facilitate adequate help and guidance as these symptoms are easily overlooked.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT03871881.


Author(s):  
Mohammad Radgoodarzi ◽  
Elahe Norouzi ◽  
Zahra Vahedi ◽  
Mitra Salavati ◽  
Ameneh Yaghoubi ◽  
...  

Background: Congenital heart defects (CHDs) are the most common congenital malformations at birth. Substance abuse has increased dramatically over the past two decades. It also can affect neonates of drug-abusing mothers. Objectives: This study aimed to elucidate the possible association of maternal drug abuse with CHDs in their newborn infants. Patients and Methods: In this study, 72 neonates who were born during 6 years in three teaching hospitals are studied. Echocardiography was performed by a single pediatric cardiologist using two-dimensional and color Doppler echocardiography. The data were analyzed using descriptive statistics. Results: 1) Of 72 included cases, 38 (52.78%) had abnormal echocardiographic findings; 2) from 38 abnormal echocardiography, 35 (48.61% of total and 92.11% of abnormal echoes) had mild congenital heart defect (CHD), and 3 had complex CHD; 3) There was no significant difference in the prevalence of neonatal congenital heart defect with the type of misused drugs (opiates or methamphetamines). Conclusions: In our study, the prevalence of CHD in newborns of drug abuser mothers was significantly higher than the normal population of infants. Hence, echocardiographic screening of these newborns seems to be logical.


Praxis medica ◽  
2020 ◽  
Vol 49 (3-4) ◽  
pp. 55-59
Author(s):  
Ljubiša Mirić ◽  
Tijana Smiljković ◽  
Vladan Perić ◽  
Slađana Mirić ◽  
Tjaša Ivošević

Introduction: Ebstein anomaly, a congenital heart defect characterized by a morphological and functional abnormality of the tricuspid valvula while moving the mouth of the tricuspid valvula towards the apex of the right chamber. Case report: A patient aged 39 years on the Department of Surgery was admitted under the image of an acute abdomen and the need for emergency surgical treatment. Routine preoperative preparation, laboratory treatment, examination of internist and examination of anesthesiologist on the part of the part was carried out. He has a history of occasional breathing problems during respiratory infection, a smoker. Clinical status, other than primary problems, is orderly. Operational treatment passed neatly, on the fourth postoperative day the patient complained of suffocation, lack of air and chest pain, translated into intensive care monitored (spo2 87% f about 110/min TA 90/60), blood gas analysis done and laboratory treatment (fibrinogen, D dimer) due to suspected pulmonary thromboembolia consulted cardiologist, dilation of the right atrium seen by ultrasound. Discussion: Non-cardiac surgeries in patients with pre-existing congenital heart defects are high-risk surgeries with increased mobility and mortality in the perioperative period. In accordance with the accompanying pathoanatomical and pathophysiological changes that define the congenital heart defect, a detailed plan must be made - anesthesiological management for each patient separately. Hemodynamic and respiratory stability with avoidance of hypoxia and paradoxical arrhythmias are the basic postulates in patients with Ebstein's anomaly.


2019 ◽  
Vol 22 (4) ◽  
pp. E308-E309
Author(s):  
He Fan ◽  
Weng Jiakan ◽  
He Qicai ◽  
Qian Ximing ◽  
Chen Huaidong

Anomalies of the coronary arteries -- especially their abnormal origin from the pulmonary artery (ARCAPA) trunk -- are among the least common. They’re also the most dangerous of congenital heart defects with an incidence of 0.002% in the general population [Williams 2006]. The diagnosis exceedingly is difficult because anatomical abnormalities of the coronary arteries are subtle. We present a case of an anomalous origin of the right coronary artery.


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