scholarly journals Researches on the Pharmacological Effects of Eicosapentaenoic Acid

2015 ◽  
Vol 3 (4) ◽  
Author(s):  
Pang Z ◽  
Zhang Q ◽  
Tian Z ◽  
Han C
Keyword(s):  
Eicosapentaenoic Acid ◽  
Pharmacological Effects

scholarly journals Researches on the Pharmacological Effects of Eicosapentaenoic Acid

2015 ◽  
Vol 3 (1) ◽  
pp. 4-7
Author(s):  
Zunting Pang ◽  
Qiang Zhang ◽  
Zhixiang Tian ◽  
Chunchao Han
Keyword(s):  
Eicosapentaenoic Acid ◽  
Pharmacological Effects

Ultrastructure of neuromuscular relationships in the canine heartworm (dirofilaria immitis)

1986 ◽  
Vol 44 ◽  
pp. 278-279
Author(s):  
W. L. Steffens ◽  
Nancy B. Roberts ◽  
J. M. Bowen
Keyword(s):  
Dirofilaria Immitis ◽  
Domestic Dogs ◽  
Structural Description ◽  
Pharmacological Effects ◽  
Free Living ◽  
Canine Heartworm ◽  
The World ◽  
Synaptic Region ◽  
Muscle Innervation ◽  
Insight Into

The canine heartworm is a common and serious nematode parasite of domestic dogs in many parts of the world. Although nematode neuroanatomy is fairly well documented, the emphasis has been on sensory anatomy and primarily in free-living soil species and ascarids. Lee and Miller reported on the muscular anatomy in the heartworm, but provided little insight into the peripheral nervous system or myoneural relationships. The classical fine-structural description of nematode muscle innervation is Rosenbluth's earlier work in Ascaris. Since the pharmacological effects of some nematacides currently being developed are neuromuscular in nature, a better understanding of heartworm myoneural anatomy, particularly in reference to the synaptic region is warranted.

Eicosapentaenoic acid

2011 ◽  
Author(s):  
Samia Burridge
Keyword(s):  
Eicosapentaenoic Acid

Salvia phytomedicines: from the „salvãre„ properties to demonstration of some pharmacological effects

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
CF Lima ◽  
AA Ramos ◽  
C Pereira-Wilson ◽  
MJ Sousa ◽  
PS Braga ◽  
...  
Keyword(s):  
Pharmacological Effects

Eicosapentaenoic Acid Interferes with U46619-Stimulated Formation of Inositol Phosphates in Washed Rabbit Platelets

1989 ◽  
Vol 62 (04) ◽  
pp. 1116-1120 ◽  
Author(s):  
N Chetty ◽  
J D Vickers ◽  
R L Kinlough-Rathbone ◽  
M A Packham ◽  
J F Mustard
Keyword(s):  
Signal Transduction ◽  
Fatty Acid Composition ◽  
Eicosapentaenoic Acid ◽  
Inositol Phosphates ◽  
Inositol Phosphate ◽  
Dense Granule ◽  
Detectable Change ◽  
Membrane Phospholipids ◽  
Rabbit Platelets ◽  
Stimulation Of

SummaryEicosapentaenoic acid (EPA) inhibits platelet responsiveness to aggregating agents. To investigate the reactions that are affected by EPA, we examined the effect of preincubating aspirintreated rabbit platelets with EPA on stimulation of inositol phosphate formation in response to the TXA2 analogue U46619. Stimulation of platelets with U46619 (0.5 μM) caused aggregation and slight release of dense granule contents; aggregation and release were inhibited by preincubation of the platelets with EPA (50 μM) for 1 h followed by washing to remove unincorporated EPA. Incubation with EPA (50 μM) for 1 h did not cause a detectable increase in the amount of EPA in the platelet phospholipids. When platelets were prelabelled with [3H]inositol stimulation with U46619 of control platelets that had not been incubated with EPA significantly increased the labelling of mos1tol phosphates. The increases in inositol phosphate labelling due to U46619 at 10 and 60 s were partially inhibited by premcubat10n of the platelets with 50 μM EPA. Since the activity of cyclo-oxygenase was blocked with aspirin, inhibition of inositol phosphate labelling in response to U46619 indicates either that there may be inhibition of signal transduction without a detectable change in the amount of EPA in platelet phospholipids, that changes in signal transduction require only minute changes in the fatty acid composition of membrane phospholipids, or that after a 1 h incubation with EPA, activation of phospholipase C is affected by a mechanism that is not directly related to incorporation of EPA.

Decrease of Platelet Activity After Intake of Small Amounts of Eicosapentaenoic Acid in Diabetics

1982 ◽  
Vol 48 (03) ◽  
pp. 344-344 ◽  
Author(s):  
B Velardo ◽  
M Lagarde ◽  
M Guichardant ◽  
M Dechavanne ◽  
M Beylot ◽  
...  
Keyword(s):  
Eicosapentaenoic Acid ◽  
Platelet Activity

Dunaliella salina Teod. as a Prominent Source of Eicosapentaenoic Acid

2010 ◽  
Vol 12 (2) ◽  
pp. 185-189 ◽  
Author(s):  
Rahul A. Bhosale ◽  
M. P. Rajabhoj ◽  
B. B. Chaugule
Keyword(s):  
Eicosapentaenoic Acid ◽  
Dunaliella Salina

612-P: Eicosapentaenoic Acid (EPA) Inhibits Human HDL Oxidation in a Concentration-Dependent Manner at a Pharmacologic Dose In Vitro

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 612-P
Author(s):  
SAMUEL SHERRATT ◽  
R. PRESTON MASON
Keyword(s):  
Eicosapentaenoic Acid ◽  
Dependent Manner ◽  
Concentration Dependent Manner
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