scholarly journals Spontaneous coronary artery dissection as a marker of undifferentiated connective tissue dysplasia: a case report

2021 ◽  
Vol 20 (7) ◽  
pp. 2973
Author(s):  
Ya. B. Khovaeva ◽  
A. L. Korovin ◽  
Ya. A. Sychugov ◽  
L. V. Ermachkova ◽  
N. P. Moiseenko

The article presents a case report of spontaneous coronary artery dissection (SCAD) in the young woman with signs of undifferentiated connective tissue dysplasia (UCTD). The patient was admitted urgently with a clinical and electrocardiographic signs of acute ST-segment elevation coronary syndrome. The patient underwent a coronary angiography, which revealed a type D linear intimal dissection. The decision was made to perform balloon vasodilation with the placement of a drug-eluting stent. With multicomponent therapy, the patient’s condition improved. Physical examination revealed external markers of UCTD. Therefore, it was quantified by systems and organs. The patient had no other cardiovascular diseases, previous infection, or other trigger factors. She was discharged with recommendations to continue the prescribed therapy. This case report demonstrates SCAD as a rare cause of acute myocardial infarction in a young patient. The background for SCAD development in this case was UCTD. Algorithms for managing patients with SCAD against the background of UCTD have not been defined and require further study.

2015 ◽  
Vol 5 (1) ◽  
pp. 52-57
Author(s):  
Tunaggina Afrin Khan ◽  
Abdul Wadud Chowdhury ◽  
Abu Sadique Abdullah

Spontaneous coronary artery dissection is an extremely rare cause of acute coronary syndrome. Although it predominantly affects young women in the peripartum period, it can also occur in men. The left coronary artery is most frequently involved. The usual presentation is ST segment elevation myocardial infarction. Although several treatment modalities have been proposed, the optimal treatment options still remain to be established. This current case report focuses on a 40- year-old male presented with acute coronary syndrome and subsequently was found to have coronary artery dissection. DOI: http://dx.doi.org/10.3329/jemc.v5i1.21498 J Enam Med Col 2015; 5(1): 52-57


2021 ◽  
Vol 29 ◽  
pp. 1-5
Author(s):  
Stéphany Bastos ◽  
Raquel Carbelin ◽  
José Francisco ◽  
Gustavo Matos ◽  
Evandro Matos Júnior ◽  
...  

Spontaneous coronary artery dissection is an uncommon condition, and the patients’ clinical presentation is often underestimated due to few risk factors for atherosclerotic disease. Treatment must be individualized, with conservative therapy as the first option, respecting the criteria for referral for interventional treatment. We report a case of spontaneous coronary dissection, initially manifested as a non-ST segment elevation acute coronary syndrome, progressing to transmural infarction, in a young patient, with few risk factors for coronary artery disease, and give examples of difficulties related to the percutaneous approach.


2021 ◽  
Vol 36 (2) ◽  
pp. 151-157
Author(s):  
Kajal Kumar Karmoker ◽  
Bijoy Dutta ◽  
Mohammad Bazlur Rashid ◽  
Mohammad Ashraful Alam ◽  
ABM Riaz Kawsar ◽  
...  

Background: Spontaneous coronary artery dissection (SCAD) is frequently underdiagnosed and often considered as a rare cause of acute coronary syndrome (ACS). Although it predominantly affects young women in the peripartum period, it can also occur in men. Most of the reported dissections have occurred in the left anterior descending coronary artery. The optimal treatment modalities are yet to be defined. Case Summary: A 50- year-old man who presented to us at National Institute of Cardio-Vascular Diseases (NICVD), Dhaka with an acute Non-ST-elevation myocardial infarction secondary to a spontaneous dissection of the Left anterior descending coronary artery. Due to ongoing chest pain, percutaneous coronary intervention (PCI) was done with drug eluting stent (DES) successfully, and the patient was discharged from the hospital on medical therapy. Conclusion: All clinicians should remain vigilant and aware of this condition, as patient outcomes and treatment guidelines differ substantially from conventional atherosclerotic ACS. Although initial conservative strategy is preferred strategy in SCAD management but timely intervention is warranted in selected cases. Bangladesh Heart Journal 2021; 36(2): 151-157


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Tatsuo Haraki ◽  
Ryota Uemura ◽  
Shin-ichiro Masuda ◽  
Takeshi Lee

Spontaneous coronary artery dissection (SCAD) is a rare condition that may have a serious outcome because of acute coronary syndrome. The condition especially affects young women. We evaluated a middle-aged male patient with a non-ST segment elevation myocardial infarction caused by multivessel SCAD. The SCAD had occurred in the distal right coronary artery (RCA), the mid left anterior descending artery (LAD), and the distal LAD at the same time. His culprit lesion was in the distal RCA, but the SCAD had progressed more proximally within the RCA 12 days later with no clinical symptoms. We treated the mid LAD with implantation of a drug-eluting stent on admission and the SCAD had not progressed 12 days later. Moreover, the SCAD in the distal RCA and distal LAD healed spontaneously 12 days later. He had no recurrent attack, and all SCAD lesions of the RCA and LAD had completely healed 6 months later. Given that SCAD appears in various forms over the clinical course, a strategy of intervention needs careful consideration.


2020 ◽  
Vol 4 (5) ◽  
pp. 1-6
Author(s):  
Kåre Peter Frederiksen ◽  
Helle Søholm ◽  
Ole Havndrup ◽  
Kristina Procida

Abstract Background In patients suspected of acute coronary syndrome, but where the coronary angiography (CAG) has shown unobstructed coronary arteries differential diagnoses include spontaneous coronary artery dissection and takotsubo cardiomyopathy. This case report presents a patient with spontaneous coronary artery dissection but diagnostic signs suspicious of takotsubo cardiomyopathy. Which leads to a consideration of the co-existence of the diseases. Case summary A 57-year-old woman was acutely admitted to the emergency ward with sudden development of chest discomfort, palpitations, and dyspnoea. At hospitalization, the electrocardiography showed T-wave inversions in I, aVL, and V2, and Troponin I was elevated. Initial echocardiography revealed apical akinesia consistent with takotsubo cardiomyopathy. Initially, a diagnosis of acute coronary syndrome or takotsubo cardiomyopathy was suspected. The patient was further diagnostically assessed with CAG including optical coherence tomography which showed spontaneous coronary artery dissection in the left anterior descending artery. At follow-up 3 months later, CAG showed a fully healed coronary artery, and repeated echocardiography showed normalization of the left ventricular function. Discussion In this case report, initially, acute coronary syndrome was suspected due to electrocardiography with T-wave inversions and elevated cardiac biomarkers. Takotsubo cardiomyopathy was suspected when echocardiography showed apical ballooning, but CAG with optical coherence tomography revealed a spontaneous coronary artery dissection. Interestingly no severe obstructions of coronary arteries were seen, and follow-up echocardiography showed fully regained myocardial function. This leads to the debate as to whether this might be a case of co-existing spontaneous coronary artery dissection and takotsubo cardiomyopathy.


2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
George Joy ◽  
Hany Eissa

Background. Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome (ACS). Aortic dissection and SCAD share common aetiologies such as a fibromuscular dysplasia (FMD), Marfan, Ehlers Danlos, and more rarely systemic lupus erythematosus and Loeys-Dietz; however, SCAD has never been known to have a familial association with aortic dissection. Case Summary. This case report describes a 48-year-old woman suffering from SCAD who had a mother who died from ascending aortic dissection in her 50s. Discussion. This is the first case report to our knowledge of a patient with SCAD with a first-degree relative with aortic dissection. Our case is interesting in that it shows that if predisposition to arterial dissection was inherited from mother to daughter, one of them suffered an extremely rare manifestation of their underlying disease. It also shows that a high index of suspicion is needed for SCAD in the presence of a patient with ACS and a family history of dissection elsewhere in the arterial tree.


2020 ◽  
Vol 5 (1) ◽  
pp. 57-61
Author(s):  
Jun Du ◽  
Jianlin Du ◽  
Qiang She ◽  
Songbai Deng

Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome or sudden cardiac death. It often occurs in females with no conventional cardiovascular risk factors. Bilateral iliac artery dissection is also a rare disease. This case report describes a patient with spontaneous coronary artery dissection and iliac artery dissection. The authors believe that a conservative approach could be used as an effective therapy for a clinically stable patient.


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