scholarly journals Intraocular pressure and pupil diameter in healthy cats anesthetized with isoflurane and pre-medicated with isolated acepromazine or in combination with tramadol

2021 ◽  
Vol 73 (3) ◽  
pp. 631-638
Author(s):  
B.E. Rodrigues ◽  
A.P. Ribeiro ◽  
T.M. Amorim ◽  
A.B. Perotto ◽  
M.A. Mendes ◽  
...  

ABSTRACT The objective of this study was to determine changes on intraocular pressure (IOP) and pupil diameter (PD) in healthy cats anesthetized with isoflurane, and premedicated with acepromazine alone or in combination with tramadol. Thirty cats were allocated in two groups (n=15/each) and were treated with acepromazine (AG) or acepromazine/tramadol (ATG). PD and IOP were assessed before and following 30 (PM1), and 40 minutes (PM2) of treatments. Anesthesia was induced with propofol, and IOP and DP were recorded (A10) at 10 minute intervals until the end of anesthesia (A40). IOP decreased in AG and ATG, when comparing baseline with PM1. IOP decreased only in AG, in comparisons between baseline and PM2. During anesthesia, IOP did not change within and between groups. Comparisons between baseline with those recorded at PM1 and 2 showed that PD increased in the ATG. During anesthesia, PD decreased significantly in AG and ATG. Both protocols maintained the IOP within the reference range to perform corneal or intraocular surgery in healthy cats but did not sustain pre-anesthetic pupil dilation observed in ATG.

2018 ◽  
Vol 48 (3) ◽  
Author(s):  
Deise Cristine Schroder ◽  
Bianca Garay Monteiro ◽  
Deborah Braga Pytlak ◽  
Mayara Carvalho de Souza ◽  
Adriane Jorge Mendonça ◽  
...  

ABSTRACT: This study aimed to investigate the effects of the systemic administration of acepromazine, tramadol and the association of both on intraocular pressure (IOP) and pupil diameter (PD) in young healthy cats. Cats were randomly allocated into three groups (n=10/each) and intramuscular acepromazine (AG), tramadol (TG) or acepromazine combined with tramadol (ATG) were injected. PD (electronic caliper) and IOP (applanation tonometry) were assessed before (baseline) and following 15, 30, 60, and 120 minutes of treatments. It was verified that in AG, PD decreased significantly from time point 30 to 120 (P=0.002), but such reduction did not differ significantly from baseline (P=0.89). In TG, PD increased significantly from the first 15 minutes, until the last time point of evaluation (P<0.001). In ATG, PD increased significantly from time point 30 to 120 when compared to baseline (P<0.001); but significant differences from time point 30 to 120 were not seen (P=0.71). Comparisons among groups showed that PD values of TG and ATG were significantly higher than that of AG (P<0.05). IOP values, on the other hand, did not change significantly among time points and groups (P>0.05). It can be concluded that tramadol alone or in association with acepromazine produced significant mydriasis for up to 120 minutes, without changing IOP values in normal cats. Results of this study suggested that tramadol alone or in association with acepromazine caused significant mydriasis and did not change IOP values in normal cats. Therefore, it may be considered a satisfactory pre-anesthetic combination for ophthalmic surgery in cats. However, further studies are warranted on the use of such protocols in cats with ophthalmic diseases undergoing ocular or intraocular surgery.


2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
A-Yong Yu ◽  
Hua Guo ◽  
Qin-Mei Wang ◽  
Fang-Jun Bao ◽  
Jing-Hai Huang

Objective. To investigate mydriatic effect of intracamerally injected epinephrine hydrochloride during phacoemulsification and intraocular lens (IOL) implantation.Methods. Eighteen cataract patients for bilateral phacoemulsification were enrolled. To dilate pupil, one eye was randomly selected to receive intracamerally 1 mL epinephrine hydrochloride 0.001% for 1 minute after corneal incision (intracameral group), and the contralateral eye received 3 drops of compound tropicamide 0.5% and phenylephrine 0.5% at 5-minute intervals 30 minutes before surgery (topical group). Pupil diameters were measured before corneal incision, before ophthalmic viscoelastic device (OVD) injection, after OVD injection, before IOL implantation, and at the end of surgery.Results. At each time point, the mean pupil diameter in the intracameral group was2.20±0.08,5.09±0.20,6.76±0.19,6.48±0.18, and5.97±0.24 mm, respectively, and in the topical group it was7.98±0.15,7.98±0.15,8.53±0.14,8.27±0.16, and7.93±0.20 mm, respectively. The topical group consistently had larger mydriatic effects than the intracameral group (P<0.05). The onset of mydriatic effect was rapid in the intracameral group. There was no difference in surgical performance or other parameters between groups.Conclusions. Intracameral epinephrine hydrochloride appears to be an alternative to the mydriatic modalities for phacoemulsification and IOL implantation. In comparison with topical mydriatics, intracameral epinephrine hydrochloride offers easier preoperative preparation, more rapid pupil dilation, and comparable surgical performance.


2013 ◽  
Vol 17 (6) ◽  
pp. 397-402 ◽  
Author(s):  
Alexandre P. Ribeiro ◽  
Roberta M. Crivelaro ◽  
Pedro Paulo M. Teixeira ◽  
Dunia Y. Trujillo ◽  
Patrícia J. Guimarães ◽  
...  

2020 ◽  
Vol 17 (3) ◽  
pp. 285-289
Author(s):  
Rachel Xuan ◽  
Keith Ong

The aim of this retrospective study was to evaluate whether intraocular (IOP) elevation post-cataract surgery can be reduced by using tropicamide and phenylephrine only, without cyclopentolate. Medical records across two surgical facilities were analyzed. One surgical facility (Cohort A) used a combination of tropicamide, cyclopentolate, and phenylephrine preoperatively, while the other (Cohort B) used tropicamide and phenylephrine only. Of patients in Cohort A, 63.6% (n = 7) had a higher IOP in the operated eye, while it was only 27.3% (n = 3) in Cohort B. Therefore, it is preferable to exclude the use of cyclopentolate in the preoperative dilation regimen of patients undergoing cataract surgery. However, a study with a larger sample population is required to further evaluate the significance of these results.


2012 ◽  
Vol 16 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Liga Kovalcuka ◽  
Edite Birgele ◽  
Dace Bandere ◽  
David L. Williams

2019 ◽  
Vol 47 (3) ◽  
pp. 1-10
Author(s):  
Kiho Kim ◽  
Yeonsil Lee ◽  
Hui-Teak Kim ◽  
Jang-Han Lee

We investigated the effects of auditory and visual stimuli on pupil dilation induced by emotional arousal during deception. The 33 participants were free to select to be in either a guilty or a not-guilty group. The guilty group performed a theft crime mission, and the not-guilty group performed a legal mission. To detect deception, we measured their pupil diameter with an eye tracker, and they completed the Control Question Test that is typically employed in polygraph tests, and which is based on a comparison of physiological responses to crime-relevant questions and comparison questions. This test was presented via one of three stimuli: auditory, visual, or dual sensory (auditory and visual simultaneously). The findings revealed that the diameter of the pupils of the guilty group increased differently according to the question type when both auditory and visual stimuli were presented simultaneously. Results suggest that pupil dilation could be the deception discriminant, and the use of more than one sensory stimulus may support lie detection in forensic investigations.


Pharmacology ◽  
2006 ◽  
Vol 77 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Juanita Dortch-Carnes ◽  
Karen R.M. Russell

2016 ◽  
Vol 20 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Jiyoon Kwak ◽  
Seonmi Kang ◽  
Eui Ri Lee ◽  
Sangwan Park ◽  
Sungwon Park ◽  
...  

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