scholarly journals Global Expression-Based Classification of Lymph Node Metastasis and Extracapsular Spread of Oral Tongue Squamous Cell Carcinoma

Neoplasia ◽  
2006 ◽  
Vol 8 (11) ◽  
pp. 925-932 ◽  
Author(s):  
Xiaofeng Zhou ◽  
Stephane Temam ◽  
Myungshin Oh ◽  
Nisa Pungpravat ◽  
Bau-Lin Huang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Oral Tongue ◽  
Extracapsular Spread ◽  
Node Metastasis

scholarly journals Subnetwork representation learning for discovering network biomarkers in predicting lymph node metastasis in early oral cancer

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Minsu Kim ◽  
Sangseon Lee ◽  
Sangsoo Lim ◽  
Doh Young Lee ◽  
Sun Kim
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Oral Tongue ◽  
Node Metastasis ◽  
Network Biomarkers

AbstractCervical lymph node metastasis is the leading cause of poor prognosis in oral tongue squamous cell carcinoma and also occurs in the early stages. The current clinical diagnosis depends on a physical examination that is not enough to determine whether micrometastasis remains. The transcriptome profiling technique has shown great potential for predicting micrometastasis by capturing the dynamic activation state of genes. However, there are several technical challenges in using transcriptome data to model patient conditions: (1) An Insufficient number of samples compared to the number of genes, (2) Complex dependence between genes that govern the cancer phenotype, and (3) Heterogeneity between patients between cohorts that differ geographically and racially. We developed a computational framework to learn the subnetwork representation of the transcriptome to discover network biomarkers and determine the potential of metastasis in early oral tongue squamous cell carcinoma. Our method achieved high accuracy in predicting the potential of metastasis in two geographically and racially different groups of patients. The robustness of the model and the reproducibility of the discovered network biomarkers show great potential as a tool to diagnose lymph node metastasis in early oral cancer.

Immunodetection of Activin A is a Marker of Occult Lymph Node Metastasis and Prognosis in Oral Tongue Squamous Cell Carcinoma

2014 ◽  
Vol 117 (2) ◽  
pp. e210
Author(s):  
PRISCILA CAMPIONI RODRIGUES ◽  
NATALIE KELNER ◽  
ANDREIA BUFALINO ◽  
FELIPE PAIVA FONSECA ◽  
ALAN ROGER DOS SANTOS SILVA ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Activin A ◽  
Tongue Squamous Cell Carcinoma ◽  
Oral Tongue ◽  
Node Metastasis ◽  
Occult Lymph Node Metastasis

P47. Detection of occult lymph node metastasis in oral tongue squamous cell carcinoma

Oral Oncology ◽  
2011 ◽  
Vol 47 ◽  
pp. S89
Author(s):  
A. Suresh ◽  
M. Jeevan ◽  
N. Trivedi ◽  
K.R. Hiran ◽  
V. Kekatpure ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Oral Tongue ◽  
Node Metastasis ◽  
Occult Lymph Node Metastasis

P-28 The potential of MET immunoreactivity for prediction of lymph node metastasis in early tongue squamous cell carcinoma

Oral Oncology ◽  
2021 ◽  
Vol 118 ◽  
pp. 12-13
Author(s):  
Maria J. de Herdt ◽  
Berdine van der Steen ◽  
Quincy van der Toom ◽  
Yassine Aaboubout ◽  
Stefan M. Willems ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tongue Squamous Cell Carcinoma ◽  
Node Metastasis

NOTCH1 mutations and extracapsular spread in oral squamous cell carcinoma lymph node metastasis

2016 ◽  
Vol 42 (11) ◽  
pp. S230
Author(s):  
Priyanka Bhattacharya ◽  
Janet Risk ◽  
Jagjit Dhanda ◽  
Richard Shaw ◽  
Bryony Lloyd ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Extracapsular Spread ◽  
Node Metastasis ◽  
Notch1 Mutations

Evaluation of progression level of extracapsular spread for cervical lymph node metastasis of oral squamous cell carcinoma

Toukeibu Gan ◽  
2014 ◽  
Vol 40 (4) ◽  
pp. 437-442
Author(s):  
Shin-ichi Yamada ◽  
Souichi Yanamoto ◽  
Hidenori Takahashi ◽  
Yuki Matsushita ◽  
Tomofumi Naruse ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cervical Lymph Node ◽  
Cervical Lymph Node Metastasis ◽  
Extracapsular Spread ◽  
Node Metastasis
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