Epidemiology of Hoffmeister's “Genetically Determined Predisposition to Disturbed Development of the Dentition” in Patients With Cleft Lip and Palate

2006 ◽  
Vol 43 (4) ◽  
pp. 457 ◽  
Author(s):  
Franka Stahl ◽  
Rosemarie Grabowski ◽  
Katrin Wigger
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Genetically Determined

Comparison of Facial Morphology in Two Populations with Complete Unilateral Cleft Lip and Palate from Two Different Centers

2006 ◽  
Vol 43 (4) ◽  
pp. 471-476 ◽  
Author(s):  
John Daskalogiannakis ◽  
Gabriëlle E. H. M. Dijkman ◽  
Anne Marie Kuijpers-Jagtman ◽  
R. Bruce Ross
Keyword(s):  
Repeated Measures ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Alveolar Bone ◽  
Craniofacial Morphology ◽  
Facial Morphology ◽  
History Of ◽  
Sick Children ◽  
Genetically Determined ◽  
Two Populations

Objective To identify differences in craniofacial morphology of two populations with a history of complete unilateral cleft lip and palate (UCLP) treated under different protocols. Design Retrospective longitudinal cohort study. Setting Cleft Center of the University of Nijmegen, The Netherlands, and the Cleft Lip and Palate Program, The Hospital for Sick Children, Toronto, Canada. Subjects Nineteen patients (16 male, 3 female) from Nijmegen and 19 patients (16 male, 3 female) from Toronto. Each patient was matched for sex and age with a patient from the other group. The mean ages at which lateral cephalometric radiographs were available for the Nijmegen group were 5.5, 9.9, and 18.3 years, while for the Toronto group these were available at mean ages of 5.3, 10.1, and 18.3 years, respectively. Eighteen patients from the Nijmegen group received an alveolar bone graft at a mean age of 9.5 years (range 8.2 to 13.5 years). None of the patients from Toronto received bone grafts. Main Outcome Measures Eighteen cephalometric variables per radiograph were calculated at each time registration, using Dentofacial Planner cephalometric software. Statistical evaluation was performed with repeated-measures analysis of variance. Results No differences were seen in the maxillary measurements. The patients in the Toronto group had significantly larger mandibles at all three time registrations. Conclusions The Nijmegen and Toronto protocols resulted in similar maxillary projections in patients with UCLP. Comparison of data from other studies supports the contention that the larger profile convexity of the Nijmegen group is a reflection of a genetically determined smaller mandibular size in the Dutch population.

Epidemiology of Hoffmeister's “Genetically Determined Predisposition to Disturbed Development of the Dentition” in Patients with Cleft Lip and Palate

2006 ◽  
Vol 43 (4) ◽  
pp. 457-465 ◽  
Author(s):  
Franka Stahl ◽  
Rosemarie Grabowski ◽  
Katrin Wigger
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Dental Anomalies ◽  
Chi Square ◽  
Chi Square Test ◽  
Bud Position ◽  
And Gender ◽  
The Individual ◽  
Genetically Determined ◽  
Deciduous Molars

Objective Type and prevalence rates of the symptoms of Hoffmeister's “genetically determined predisposition to disturbed development of the dentition” were studied in patients with clefts. Patients Data of 263 patients with nonsyndromic clefts of lip (alveolus and palate) or isolated cleft palates were examined in a retrospective study. Setting The clefts were classified as cleft lip or cleft lip and alveolus, cleft palate, unilateral cleft lip and palate, and bilateral cleft lip and palate. All patients were scrutinized for 28 individual symptoms. Prevalences of the individual symptoms were statistically evaluated regarding cleft type and gender by using the chi-square test and were also compared with findings in patients without clefts. Results In 97.7% of the patients with clefts, at least one symptom was found. Microdontia of individual teeth, hypodontia, and hyperodontia were the symptoms most frequently recorded. Comparison of the different cleft types revealed differences regarding the prevalences of supernumerary lateral incisors (p = .051), infraposition of deciduous molars (p < .001), and atypical tooth bud position (p = .030). Comparison of the prevalences of 10 symptoms recorded in the patients with clefts with the prevalences recorded in patients without clefts showed nine symptoms were found much more frequently in the population with clefts. Conclusion These findings support the hypothesis that clefting is part of a complex malformation associated with other dental anomalies resulting from disturbed development of the dentition. Patients with clefts are also likely to present other deficiencies of dental development and tooth eruption in both dentitions, even in regions not affected by the cleft.

Treating Velopharyngeal Inadequacy Using Bilateral Buccal Flap Revision Palatoplasty

2019 ◽  
Vol 4 (5) ◽  
pp. 878-892
Author(s):  
Joseph A. Napoli ◽  
Linda D. Vallino
Keyword(s):  
Systematic Review ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
A Priori ◽  
Sufficient Evidence ◽  
Obstructive Sleep ◽  
Before And After ◽  
Buccal Flap

Purpose The 2 most commonly used operations to treat velopharyngeal inadequacy (VPI) are superiorly based pharyngeal flap and sphincter pharyngoplasty, both of which may result in hyponasal speech and airway obstruction. The purpose of this article is to (a) describe the bilateral buccal flap revision palatoplasty (BBFRP) as an alternative technique to manage VPI while minimizing these risks and (b) conduct a systematic review of the evidence of BBFRP on speech and other clinical outcomes. A report comparing the speech of a child with hypernasality before and after BBFRP is presented. Method A review of databases was conducted for studies of buccal flaps to treat VPI. Using the principles of a systematic review, the articles were read, and data were abstracted for study characteristics that were developed a priori. With respect to the case report, speech and instrumental data from a child with repaired cleft lip and palate and hypernasal speech were collected and analyzed before and after surgery. Results Eight articles were included in the analysis. The results were positive, and the evidence is in favor of BBFRP in improving velopharyngeal function, while minimizing the risk of hyponasal speech and obstructive sleep apnea. Before surgery, the child's speech was characterized by moderate hypernasality, and after surgery, it was judged to be within normal limits. Conclusion Based on clinical experience and results from the systematic review, there is sufficient evidence that the buccal flap is effective in improving resonance and minimizing obstructive sleep apnea. We recommend BBFRP as another approach in selected patients to manage VPI. Supplemental Material https://doi.org/10.23641/asha.9919352

Orthodontic Management Of The Cleft Lip And Palate Patient

1993 ◽  
Vol 20 (4) ◽  
pp. 733-753 ◽  
Author(s):  
Alvaro A. Figueroa ◽  
John W. Polley ◽  
Mimis Cohen
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Palate Patient

Cleft lip and palate care in the UK: the CSAG report

BDJ ◽  
1998 ◽  
Vol 185 (7) ◽  
pp. 320-321 ◽  
Author(s):  
Biase Di ◽  
A Markus
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
The Uk

Precision of Landmark Positioning on Digitized Models from Patients with Cleft Lip and Palate

2005 ◽  
Author(s):  
Jakob Brief ◽  
Jan Behle ◽  
Angelika Stellzig-Eisenhauer ◽  
Stefan Hassfeld
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate

Objective Assessment of the Nasal Airway in Unilateral Cleft Lip and Palate - a Long-term Study

2009 ◽  
pp. 091202121239062
Author(s):  
Maria Mani ◽  
Staffan Morén ◽  
Ornolfur Thorvardsson ◽  
Olafur Jakobsson ◽  
Valdemar Skoog ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Objective Assessment ◽  
Nasal Airway ◽  
Term Study ◽  
Long Term Study
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