Human Metallothionein Expression under Normal and Pathological Conditions: Mechanisms of Gene Regulation Based on In silico Promoter Analysis

2009 ◽  
Vol 19 (4) ◽  
pp. 301-317 ◽  
Author(s):  
Debby Laukens ◽  
Anouk Waeytens ◽  
Pieter De Bleser ◽  
Claude Cuvelier ◽  
Martine De Vos
Keyword(s):  
Gene Regulation ◽  
In Silico ◽  
Promoter Analysis ◽  
Pathological Conditions

Identification of BAP1-associated MicroRNAs and Implications in Cancer Development

2019 ◽  
pp. 1-4
Author(s):  
Tikam Chand ◽  
Tikam Chand
Keyword(s):  
Gene Regulation ◽  
In Silico ◽  
Mirna Target ◽  
Target Prediction ◽  
Differential Regulation ◽  
Cancer Development ◽  
Mirna Target Prediction ◽  
Cancer Types ◽  
In Silico Tools

Having role in gene regulation and silencing, miRNAs have been implicated in development and progression of a number of diseases, including cancer. Herein, I present potential miRNAs associated with BAP1 gene identified using in-silico tools such as TargetScan and Exiqon miRNA Target Prediction. I identified fifteen highly conserved miRNA (hsa-miR-423-5p, hsa-miR-3184-5p, hsa-miR-4319, hsa-miR125b-5p, hsa-miR-125a-5p, hsa-miR-6893-3p, hsa-miR-200b-3p, hsa-miR-200c-3p, hsa-miR-505-3p.1, hsa-miR-429, hsa-miR-370-3p, hsa-miR-125a-5p, hsa-miR-141-3p, hsa-miR-200a-3p, and hsa-miR-429) associated with BAP1 gene. We also predicted the differential regulation of these twelve miRNAs in different cancer types.

Reverse Engineering of Gene Regulation Networks with an Application to the DREAM4 in silico Network Challenge

2011 ◽  
pp. 461-477 ◽  
Author(s):  
Hyonho Chun ◽  
Jia Kang ◽  
Xianghua Zhang ◽  
Minghua Deng ◽  
Haisu Ma ◽  
...  
Keyword(s):  
Gene Regulation ◽  
Reverse Engineering ◽  
In Silico ◽  
Gene Regulation Networks

Discovery of transcriptional programs in cerebral ischemia by in silico promoter analysis

2009 ◽  
Vol 1272 ◽  
pp. 3-13 ◽  
Author(s):  
Dirk A. Ridder ◽  
Svetlana Bulashevska ◽  
Ganta Vijay Chaitanya ◽  
Phanithi Prakash Babu ◽  
Benedikt Brors ◽  
...  
Keyword(s):  
Cerebral Ischemia ◽  
In Silico ◽  
Promoter Analysis

In Silico Analysis of miRNA-Mediated Gene Regulation in OCA and OA Genes

2014 ◽  
Vol 70 (3) ◽  
pp. 1923-1932 ◽  
Author(s):  
Balu Kamaraj ◽  
Chandrasekhar Gopalakrishnan ◽  
Rituraj Purohit
Keyword(s):  
Gene Regulation ◽  
In Silico ◽  
In Silico Analysis ◽  
Silico Analysis
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