scholarly journals Effect of primary iris and ciliary body cyst on anterior chamber angle in patients with shallow anterior chamber

2012 ◽  
Vol 13 (9) ◽  
pp. 723-730 ◽  
Author(s):  
Bing-hong Wang ◽  
Yu-feng Yao
Keyword(s):  
Anterior Chamber ◽  
Ciliary Body ◽  
Anterior Chamber Angle ◽  
Shallow Anterior Chamber ◽  
Chamber Angle

Anterior Chamber Angle and Iris-Lens Contact Alteration During Pupillary Dilation

2011 ◽  
Author(s):  
Sara Jouzdani ◽  
Rouzbeh Amini ◽  
Victor H. Barocas
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Aqueous Humor ◽  
Ciliary Body ◽  
Ocular Tissue ◽  
Posterior Chamber ◽  
Pupillary Dilation ◽  
Anterior Chamber Angle ◽  
Aqueous Outflow ◽  
Chamber Angle

The aqueous humor (AH) provides oxygen and nutrients for the avascular ocular tissue specifically, the cornea and lens. AH is secreted by the ciliary body into the posterior chamber, passes through pupil, and drains into the anterior chamber (Fig. 1a). Resistance to the aqueous outflow generates the intraocular pressure (IOP), which is 15–20 mmHg in the normal eyes.

scholarly journals Assessment of anterior chamber angle changes after phacoemulsification with swept-source OCT

2021 ◽  
Vol 14 (10) ◽  
pp. 1527-1532
Author(s):  
Qian Zheng ◽  
◽  
Zhang-Liang Li ◽  
Ping-Jun Chang ◽  
Yun-E Zhao ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Cataract Surgery ◽  
Anterior Chamber ◽  
Anterior Chamber Depth ◽  
Anterior Chamber Angle ◽  
Swept Source ◽  
Narrow Angle ◽  
Significant Difference ◽  
Shallow Anterior Chamber ◽  
Chamber Angle

AIM: To assess the changes of anterior chamber angle in patients with shallow anterior chamber after phacoemulsification combined with intraocular lens (IOL) implantation, based on anterior segment swept-source optical coherence tomography (AS-SS-OCT) measurements. METHODS: This was a prospective case control study; sixty eyes of sixty case were scheduled for cataract surgery with normal intraocular pressure (IOP). Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were divided into two groups: group of shallow anterior chamber and narrow angle (SAC group, 30 eyes); and group of normal anterior chamber group with wide angle (NAC group, 30 eyes). Measurements of ACD, anterior chamber volume (ACV), iris volume (IV), lens vault (LV), angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), and trabecular iris angle (TIA) were conducted in each group before and 3mo after surgery. RESULTS: There was no significant difference in age, axial length (AL), corneal curvature, corneal diameter, intraocular pressure, and IV between two groups before surgery, except for the LV (P=0.000). ACD and ACV were prominently larger in the NAC group than the SAC group 3mo after operation (3.69±0.38 vs 3.85±0.39 mm, P=0.025; 161.37±19.47 vs 178.26±20.30 mm3, P=0.002). AOD750, ARA750 in nasal and inferior quadrants, TISA750 in all quadrants except temporal, and TIA750 in all quadrants in SAC group were significantly smaller than those in NAC group after operation (all P<0.05). CONCLUSION: Cataract surgery can deepen anterior chamber and increase the width of anterior chamber angle in Chinese subjects, but the angle related parameters including AOD750, ARA750, TISA750, TIA, TISA750, and ACV in patients with shallow anterior chamber and narrow angle do not reach the normal level.

scholarly journals Penetration of Bevacizumab into the Iris, Anterior Chamber Angle and Ciliary Body After Intravitreal Injection

2009 ◽  
Vol 03 (01) ◽  
pp. 36
Author(s):  
Swaantje Peters ◽  
Peter Heiduschka ◽  
Karl-Ulrich Bartz-Schmidt ◽  
Ulrich Schraermeyer ◽  
◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Intravitreal Injection ◽  
Ciliary Body ◽  
Anterior Segment ◽  
Intravitreal Bevacizumab ◽  
Neovascular Glaucoma ◽  
Anterior Chamber Angle ◽  
Rubeosis Iridis ◽  
Endothelial Growth Factor ◽  
Chamber Angle

Recently, it was suggested that the anti-vascular endothelial growth factor (VEGF) antibody bevacizumab could be used in the treatment of rubeosis iridis. Therefore, we aimed to trace the penetration of bevacizumab into the anterior chamber after intravitreal injection of the drug. We found that intravitreally injected bevacizumab penetrates well and quickly into the anterior chamber angle, iris and ciliary body. The highest concentration of bevacizumab is present on days one to four after injection, with penetration into the iris appearing to be faster than that into the anterior chamber angle and ciliary body. These findings are consistent with the clinically described regression of iris neovascularisation one to three days after injection. Furthermore, we demonstrated progressive penetration through the tissues of the anterior chamber towards the sclera. Our study showed that the intravitreal application mode is suitable for obtaining an accumulation of bevacizumab throughout the vascularised tissues of the anterior segment. Intravitreal bevacizumab may be used as a supplementary treatment for rubeosis iridis and neovascular glaucoma.

Glaucoma Problems Associated with Aniridia

2010 ◽  
Author(s):  
Peter A. Netland
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Trabecular Meshwork ◽  
Ciliary Body ◽  
Vision Loss ◽  
Visual Field Loss ◽  
Anterior Chamber Angle ◽  
Foveal Hypoplasia ◽  
Closed Angle ◽  
Chamber Angle

Glaucoma is a potentially vision-threatening problem that is commonly encountered in aniridia patients. This condition may develop at birth, or shortly thereafter. More commonly, however, glaucoma is acquired later in childhood or even young adulthood. If unrecognized and untreated, glaucoma can result in blindness. For this reason, it is important to be vigilant in watching for this condition in children affected with aniridia. Vision lost due to glaucomatous damage cannot be regained at a later time. In addition to glaucoma, children with aniridia may demonstrate other problems with their vision. They may have refractive errors, corneal or retinal problems, or abnormalities of eye movement. Foveal hypoplasia (lack of development of the retina) may limit vision in some children. In aniridia patients, cataract (opacification or cloudiness of the lens) is seen with approximately the same prevalence as glaucoma. Cataract, however, differs from glaucoma in that the vision loss due to cataract is reversible. Glaucoma is suspected in aniridia patients when there is an increased intraocular pressure. Glaucoma can be definitely diagnosed when changes of the optic nerve occur due to this elevated intraocular pressure. At the later stages of the disease, visual field loss occurs. In the normal eye, the fluid (aqueous humor) in the front of the eye (the anterior chamber) is produced by the ciliary body, which is located behind the iris (see Figure 5.1). The fluid produced from the ciliary body flows forward into the anterior chamber, where it drains from the anterior chamber angle through tissue called the trabecular meshwork. When there is an abnormal situation, the fluid exits the eye poorly or not at all, and the intraocular pressure may be increased. The fluid may be blocked from exiting the eye by a closed angle, or may flow poorly out of the eye even though the angle is open (see Figure 5.2). The angle may be closed in aniridic patients when the stump of residual iris covers the trabecular meshwork in the anterior chamber angle.

Ciliary Body and Iris Metastases With Anterior Chamber Angle Infiltration

2020 ◽  
Vol 29 (3) ◽  
pp. e12-e15
Author(s):  
Andrew J. Swampillai ◽  
Adam P. Booth ◽  
Victoria M.L. Cohen
Keyword(s):  
Anterior Chamber ◽  
Ciliary Body ◽  
Anterior Chamber Angle ◽  
Chamber Angle

scholarly journals Assessment of anterior chamber configuration changes after phacoemulsification with swept-source optical coherence tomography

2020 ◽  
Author(s):  
Man Hu ◽  
Qian Zheng ◽  
Zhangliang Li ◽  
Pingjun Chang ◽  
Yun-e Zhao
Keyword(s):  
Optical Coherence Tomography ◽  
Cataract Surgery ◽  
Anterior Chamber ◽  
Optical Coherence ◽  
Anterior Chamber Angle ◽  
Swept Source ◽  
Narrow Angle ◽  
Significant Difference ◽  
Shallow Anterior Chamber ◽  
Chamber Angle

Abstract Background: To assess the changes of anterior chamber angle in patients with shallow anterior chamber and normal anterior chamber after phacoemulsification and intraocular lens implantation (IOL) using anterior segment swept-source optical coherence tomography (AS-SS-OCT). Methods: This was a prospective case control study; 60 eyes of 60 patients who scheduled for cataract surgery with normal intraocular pressure (IOP). Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were classified into two groups: shallow anterior chamber group with narrow angle (SAC group, 30 eyes)；and normal anterior chamber group with wide angle (NAC group, 30 eyes). Measurements of ACD, anterior chamber volume (ACV), Iris volume (IV), lens vault (LV) , angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), and trabecular iris angle (TIA) were conducted in each group before and 3 months after surgery. Differences between the two groups were compared. Results: There was no significant difference in age, axial length (AL), corneal curvature, corneal diameter, IOP and IV between the SAC group and the NAC group before operation, except for the LV (p = 0.000). All angle parameters including ACD, ACV, AOD, ARA, TISA and TIA in both groups at 3 months post-surgery were significantly different from the preoperative values (p<0.01). In addition, there were significant differences in all angle parameters between two groups before and after operation (All P< 0.05). Besides, the TISA750 in superior quadrant, ACD and ACV were significantly smaller in the group of SAC than those in the group of NAC 3 months after operation (P = 0.041, 0.001 and 0.002, respectively). Conclusions: Cataract surgery can deepen anterior chamber and increase the width of anterior chamber angle in Chinese subjects, but the ACD and ACV in patients with shallow anterior chamber and narrow angle have not reached the normal level, presumably because the iris root of SAC group inserted more anteriorly than that of NAC group. Phacoemulsification may not completely eliminate the risk of glaucoma in NAC group of people after surgery.

scholarly journals Evaluation of Anterior Chamber Depth and Anterior Chamber Angle Changing After Phacoemulsification in the Primary Angle Close Suspect Eyes

2019 ◽  
Vol 7 (24) ◽  
pp. 4297-4300
Author(s):  
Anh Tuan Vu ◽  
Van Anh Bui ◽  
Hai Long Vu ◽  
Do Quyet ◽  
Than Van Thai ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Intraocular Lens ◽  
Anterior Chamber Depth ◽  
Angle Closure ◽  
Control Group ◽  
Anterior Chamber Angle ◽  
Interventional Study ◽  
Primary Angle Closure ◽  
Shallow Anterior Chamber ◽  
Chamber Angle

BACKGROUND: Phacoemulsification surgery has the ability to deeply alter the segment anterior morphology, especially in eye with shallow anterior chamber (AC), narrow anterior chamber angle (ACA). However, the changes of anterior chamber depth (ACD) and ACA on the close angle suspect eyes after phacoemulsification have not been mentioned in many studies. So, we conduct this research. AIM: To evaluate the alteration in the ACA and ACD after phacoemulsification in the close angle suspect eyes. METHODS: Interventional study with no control group. Subjects were the primary angle closure suspect (PACS) eyes, that were operated by phacoemulsification with intraocular lens (IOL) at Glaucoma Department of VNIO from December 2017 to October 2018. RESULTS: 29 PACS eyes with cataract were operated by phacoemulsification with intraocular lens. After 3 months of monitoring, the average ACD augmented from 2.082 ± 0.244 to 3.673 ± 0.222 mm. AOD500 increase from 0.183 ± 0.088 to 0.388 ± 0.132 μm, AOD750 increased from 0.278 ± 0.105 to 0.576 ± 0.149 μm. The TISA500 enlarged from 0.068 ± 0.033 to 0.140 ± 0.052 mm2, TISA750 enlarged from 0.125 ± 0.052 to 0.256 ± 0.089 mm2 at the third month (p < 0.01). CONCLUSION: Phacoemulsification surgery increases the ACD and enlarged the angle in the PACS eyes.

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