Central Nervous System Metastases in HER‐2–Positive Metastatic Breast Cancer Patients Treated with Trastuzumab: Incidence, Survival, and Risk Factors

2007 ◽  
Vol 12 (7) ◽  
pp. 766-773 ◽  
Author(s):  
Stefania Gori ◽  
Simonetta Rimondini ◽  
Verena De Angelis ◽  
Mariantonietta Colozza ◽  
Giancarlo Bisagni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Cancer Patients ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Central Nervous System Metastases ◽  
Her 2

scholarly journals Glycoprotein M6A (GPM6A) is over-expressed in brain metastatic breast cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Microarray Data ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Significant Differential Expression ◽  
Central Nervous System Metastases ◽  
The Brain

One study reported the incidence of central nervous system metastases in breast cancer patients treated with trastuzumab as 34% (1). We mined published microarray data (2, 3) to discover genes associated with brain metastasis in breast cancer. We identified significant differential expression of glycoprotein M6A, encoded by GPM6A (4, 5), in the brain metastases of patients with metastatic breast cancer. GPM6A may be relevant to the biology underlying colonization of the brain with metastatic breast cancer clones.

scholarly journals The L-type lectin LMAN2 is over-expressed in brain metastatic breast cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Microarray Data ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Significant Differential Expression ◽  
Central Nervous System Metastases ◽  
The Brain

One study reported the incidence of central nervous system metastases in breast cancer patients treated with trastuzumab as 34% (1). We mined published microarray data (2, 3) to discover genes associated with brain metastasis in breast cancer. We identified significant differential expression of the L-type lectin LMAN2 (4-7), also known as VIP36, in patients with breast cancer. LMAN2 may be relevant to the biology underlying colonization of the brain with metastatic breast cancer clones.

scholarly journals Ma1 antigen (PNMA1) is over-expressed in brain metastatic breast cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Microarray Data ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Significant Differential Expression ◽  
Central Nervous System Metastases ◽  
The Brain

One study reported the incidence of central nervous system metastases in breast cancer patients treated with trastuzumab as 34% (1). We mined published microarray data (2, 3) to discover genes associated with brain metastasis in breast cancer. We identified significant differential expression of the paraneoplastic Ma1 antigen, encoded by the PNMA1 gene, in the brain metastases of patients with breast cancer. PNMA1 may be relevant to the biology underlying colonization of the brain with metastatic breast cancer clones.

scholarly journals ZNF432 is over-expressed in brain metastatic breast cancer.

2020 ◽  
Author(s):  
Shahan Mamoor
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Microarray Data ◽  
Metastatic Breast ◽  
Breast Cancer Patients ◽  
Significant Differential Expression ◽  
Central Nervous System Metastases ◽  
The Brain

One study reported the incidence of central nervous system metastases in breast cancer patients treated with trastuzumab as 34% (1). We mined published microarray data (2, 3) to discover genes associated with brain metastasis in breast cancer. We identified significant differential expression of ZNF432 in patients with breast cancer. ZNF432 may be relevant to the biology underlying colonization of the brain with metastatic breast cancer clones.

Central nervous system metastases in women with HER-2 positive metastatic breast cancer after treatment with trastuzumab

2006 ◽  
Vol 2 (1) ◽  
pp. 50-56 ◽  
Author(s):  
Sarah-Jane DAWSON ◽  
Nadia F RANIERI ◽  
Raymond D SNYDER ◽  
Sue-Anne McLACHLAN ◽  
William I BURNS ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Metastatic Breast Cancer ◽  
Metastatic Breast ◽  
Central Nervous System Metastases ◽  
Her 2
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