Role of the genes, NOS1 and CREB1, in a mouse model of fetal alcohol syndrome

2021 ◽  
Author(s):  
Dylan Weston Todd
2014 ◽  
Vol 210 (5) ◽  
pp. 466.e1-466.e5 ◽  
Author(s):  
Alexandria J. Hill ◽  
Nathan Drever ◽  
Huaizhi Yin ◽  
Esther Tamayo ◽  
George Saade ◽  
...  

2003 ◽  
Vol 189 (3) ◽  
pp. 790-793 ◽  
Author(s):  
Sarah H Poggi ◽  
Katie Goodwin ◽  
Joanna M Hill ◽  
Douglas E Brenneman ◽  
Elizabetta Tendi ◽  
...  

2003 ◽  
Vol 189 (3) ◽  
pp. 786-789 ◽  
Author(s):  
Sarah H Poggi ◽  
Katie M Goodwin ◽  
Joanna M Hill ◽  
Douglas E Brenneman ◽  
Elisabetta Tendi ◽  
...  

1995 ◽  
Vol 73 (9) ◽  
pp. 1209-1223 ◽  
Author(s):  
James D. Reynolds ◽  
James F. Brien

The purpose of this article is to review the current state of knowledge of ethanol neurobehavioural teratogenesis and its postulated mechanisms. The review comprises an examination of ethanol teratogenesis in the human, including the fetal alcohol syndrome, and in experimental animals. Several current proposed mechanisms of ethanol neurobehavioural teratogenesis are critically assessed, including the role of acetaldehyde as the proximate metabolite of ethanol; fetal hypoxia; placental dysfunction; fetal prostaglandin metabolism; and action of ethanol on developing neurons in the fetal brain, including the hippocampus, one of ethanol's main target sites. The effect of ethanol on the release of L-glutamate, an excitatory amino acid neurotransmitter, in the fetal hippocampus is described, and the role of L-glutamate in ethanol teratogenesis involving the hippocampus is discussed. A novel mechanism for abnormal neuronal development in the fetal hippocampus produced by prenatal ethanol exposure is presented, and future experiments to test this hypothesis are proposed.Key words: ethanol neurobehavioural teratogenesis, fetal alcohol syndrome, hippocampus, L-glutamate.


Author(s):  
Patrick Morrissette

This paper discusses the experiences of foster/adoptive parents who raise children diagnosed with Fetal Alcohol Syndrome and the instrumental role family counselors can play regarding child management issues, intimate relationships, larger system collaboration, and research. For the actual study, six parents participated in individual, in-depth tape-recorded interviews. Each interview was transcribed, thematically analyzed, and revealed seven predominant themes including (a) constant vigil, (b) effects on marriages, (c) child management, (d) parental issues, (e) interactions with professional community, (f) emancipation concerns, and (g) medical implications. The ways in which family counselors can intervene are reviewed and include the role of clinician, facilitator, and researcher/educator.


2013 ◽  
Vol 208 (1) ◽  
pp. S177
Author(s):  
Alexandria Hill ◽  
Huazhi Yin ◽  
Ester Tamayo ◽  
Nathan Drever ◽  
George Saade ◽  
...  

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