Microscopic polyangiitis associated with antineutrophil cytoplasmic antibodies: Clinical features

2015 ◽  
Vol 87 (5) ◽  
pp. 33 ◽  
Author(s):  
T. V. Beketova
2018 ◽  
Vol 90 (6) ◽  
pp. 55-58
Author(s):  
E M Shchegoleva ◽  
N M Bulanov ◽  
P I Novikov ◽  
S V Moiseev

Aim. To evaluate clinical features and outcomes of renal involvement in patients with microscopic polyangiitis (MPA). Materials and methods: We enrolled 99 patients with MPA, diagnosed in accordance with the algorithm of the European Medicines Evaluation Agency (EMEA) and the Chapel Hill consensus conference definition (2012). Serum creatinine (sCr), estimated glomerular filtration rate (eGFR), hematuria and proteinuria were estimated. Frequency of rapidly progressive renal failure (a twofold increase in the sCr level in ≤3 months) was regarded as the clinical equivalent of rapidly progressive glomerulonephritis (RPGN). Results and discussion. Renal involvement was present in 92 (92.9%) patients. RPGN developed in 51 (55,4%) patients. The most common features of kidney involvement were hematuria and subnephrotic proteinuria. Arterial hypertension was revealed in 32 (34.7%) patients and was associated with RPGN (p


2004 ◽  
Vol 11 (5) ◽  
pp. 359-362 ◽  
Author(s):  
George S Rashed Philteos ◽  
Kelly Coverett ◽  
Rajni Chibbar ◽  
Heather A Ward ◽  
Donald W Cockcroft

Several inorganic dust lung diseases (pneumoconioses) are associated with autoimmune diseases. Although autoimmune serological abnormalities are common in asbestosis, clinical autoimmune/collagen vascular diseases are not commonly reported. A case of pulmonary asbestosis complicated by perinuclear-antineutrophil cytoplasmic antibody (myeloperoxidase) positive probable microscopic polyangiitis (glomerulonephritis, pericarditis, alveolitis, multineuritis multiplex) is described and the possible immunological mechanisms whereby asbestosis fibres might be relevant in induction of antineutrophil cytoplasmic antibodies are reviewed in the present report.


2009 ◽  
Vol 24 (2) ◽  
pp. 269 ◽  
Author(s):  
Ji Seon Oh ◽  
Chang-Keun Lee ◽  
Yong Gil Kim ◽  
Seong-Su Nah ◽  
Hee-Bom Moon ◽  
...  

2000 ◽  
Vol 89 (12) ◽  
pp. 2531-2533 ◽  
Author(s):  
Hidemichi Imamura ◽  
Hiroko Kobayashi ◽  
Kazumichi Abe ◽  
Takuto Hikichi ◽  
Masayuki Miyata ◽  
...  

2011 ◽  
Vol 32 (10) ◽  
pp. 2979-2986 ◽  
Author(s):  
Joong Kyong Ahn ◽  
Ji-Won Hwang ◽  
Jaejoon Lee ◽  
Chan Hong Jeon ◽  
Hoon-Suk Cha ◽  
...  

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