First Case Report of Erythema Elevatum Diutinum Involving the Glans Penis of A HIV–Positive Patient: Possible Atypical Manifestation of Immune Reconstitution Inflammatory Syndrome

2020 ◽  
Keyword(s):  
Case Report ◽  
Immune Reconstitution Inflammatory Syndrome ◽  
Immune Reconstitution ◽  
Positive Patient ◽  
Glans Penis ◽  
Hiv Positive ◽  
First Case ◽  
Erythema Elevatum Diutinum ◽  
Inflammatory Syndrome ◽  
Atypical Manifestation

scholarly journals AIDS Cholangiopathy Secondary to Cytomegalovirus as Possible Unmasking Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-Infected Individual: Case Report and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Moiz Topiwala ◽  
Nachiket Dubale ◽  
Mahender K. Medisetty ◽  
Sunil Gaikwad ◽  
Divya Patel ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Case Report ◽  
Immune Reconstitution Inflammatory Syndrome ◽  
Immune Reconstitution ◽  
Infected Individual ◽  
Individual Case ◽  
Individual Case Report ◽  
First Case ◽  
Immunodeficiency Virus ◽  
Inflammatory Syndrome

We present the first case report of cytomegalovirus (CMV) cholangiopathy as possible immune reconstitution inflammatory syndrome (IRIS) in a human immunodeficiency virus (HIV)-infected individual, within two months of starting effective HAART. The patient presented with abdominal pain, nausea, vomiting, decreased appetite, and jaundice. The patient was diagnosed on ERCP as AIDS cholangiopathy, and biopsy of the ampulla showed acute inflammation with CMV inclusion bodies. The patient underwent sphincterotomy with CBD stenting and HAART continued without use of ganciclovir or valganciclovir. On follow-up, the patient achieved clinical and histopathological cure, which was demonstrated on repeat ampullary biopsy.

scholarly journals A Case of Steroid-Responsive, COVID-19 Immune Reconstitution Inflammatory Syndrome Following the Use of Granulocyte Colony-Stimulating Factor

2020 ◽  
Vol 7 (8) ◽  
Author(s):  
Jonathan Mertens ◽  
Yassine Laghrib ◽  
Chris Kenyon
Keyword(s):  
Case Report ◽  
Immune Reconstitution Inflammatory Syndrome ◽  
Immune Reconstitution ◽  
Granulocyte Colony Stimulating Factor ◽  
Colony Stimulating Factor ◽  
Risks And Benefits ◽  
First Case ◽  
Inflammatory Syndrome ◽  
Additional Therapy ◽  
Stimulating Factor

Abstract We present a case report of a 54-year-old male with metastasized nasopharyngeal carcinoma presenting to the hospital with dyspnea, anorexia and fever. Examination revealed chemotherapy-induced pancytopenia. The patient tested positive for SARSCoV-2, but respiratory complications were mild. The patient was treated with granulocyte-colony stimulating factor (G-CSF) leading to amelioration of the neutropenia. However, severe acute respiratory distress syndrome (ARDS) occurred, prompting the diagnosis of immune reconstitution inflammatory syndrome (IRIS). GCSF is currently investigated as additional therapy in ARDS, but this case report emphasizes that risks and benefits must be carefully assessed. To our knowledge, this is the first case report of IRIS-induced ARDS in a COVID-19 patient.

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