scholarly journals Differential Pulse Anodic Voltammetric Determination of Chlorzoxazone in Pharmaceutical Formulation using Carbon Paste Electrode

2020 ◽  
Vol 67 (4) ◽  
pp. 1053-1060
Author(s):  
Sayed I. M. Zayed ◽  
Yousry M. Issa
Keyword(s):  
Carbon Paste Electrode ◽  
Supporting Electrolyte ◽  
Pulse Amplitude ◽  
Differential Pulse ◽  
Pharmaceutical Formulation ◽  
Carbon Paste ◽  
Voltammetric Method ◽  
Voltammetric Techniques ◽  
Paste Electrode

The electrochemical behavior of chlorzoxazone at the carbon paste electrode was investigated in 0.04 mol/L Britton-Robinson buffer pH 6.50 using cyclic and differential pulse voltammetric techniques. Cyclic voltammetric studies indicated that the oxidation of the drug was irreversible and controlled mainly by diffusion. Experimental and instrumental parameters were optimized (50 mV/s scan rate, 50 mV pulse amplitude, and 0.04 mol/L Britton-Robinson (BR) buffer pH 6.50 as a supporting electrolyte) and a sensitive differential pulse anodic voltammetric method has been developed for the determination of the drug over the concentration range 0.17–1.68 μg/mL chlorzoxazone, with detection and quantitation limits of 0.05 and 0.16 μg/mL, respectively. The proposed voltammetric method was successfully applied to the determinationof the drug in its pharmaceutical formulation (Myoflex tablets), and in spiked human urine samples.

scholarly journals Electrocatalytic determination of captopril using a carbon paste electrode modified with N-(ferrocenyl methylidene) fluorene-2-amine and graphene/ZnO nanocomposite

2019 ◽  
Vol 84 (2) ◽  
pp. 175-185 ◽  
Author(s):  
Mohadeseh Safaei ◽  
Hadi Beitollahi ◽  
Masoud Shishehbore ◽  
Somayeh Tajik ◽  
Rahman Hosseinzadeh
Keyword(s):  
Modified Electrode ◽  
Carbon Paste Electrode ◽  
Electrocatalytic Oxidation ◽  
Differential Pulse ◽  
Diagnostic Techniques ◽  
Carbon Paste ◽  
Pulse Voltammetry ◽  
Electrocatalytic Determination ◽  
Paste Electrode

A carbon paste electrode (CPE) was modified with N-(ferrocenylmethylidene) fluorene-2-amine and graphene/ZnO nanocomposite. The electrooxidation of captopril (CAP) at the surface of the modified electrode was studied using electrochemical approaches. The electrochemical study of the modified electrode, as well as its efficiency for the electrocatalytic oxidation of captopril, is described. The electrode was used to study the electrocatalytic oxidation of captopril, by cyclic voltammetry (CV), chronoamperometry (CHA) and differential pulse voltammetry (DPV) as diagnostic techniques. It has been found that the oxidation of captopril at the surface of modified electrode occurs at a potential of about 340 mV less positive than that of an unmodified CPE. DPV of captopril at the electrochemical sensor exhibited two linear dynamic ranges (0.1?100.0 and 100.0?800.0 ?M) with a detection limit (3?) of 0.05 ?M.

scholarly journals Voltammetric determination of the neonicotinoid insecticide thiamethoxam using a tricresyl phosphate-based carbon paste electrode

2010 ◽  
Vol 75 (5) ◽  
pp. 681-687 ◽  
Author(s):  
Zsigmond Papp ◽  
Valéria Guzsvány ◽  
Szymon Kubiak ◽  
Andrzej Bobrowski ◽  
Luka Bjelica
Keyword(s):  
Carbon Paste Electrode ◽  
Analytical Signal ◽  
Differential Pulse ◽  
Voltammetric Determination ◽  
Carbon Paste ◽  
Tricresyl Phosphate ◽  
Relative Standard ◽  
Neonicotinoid Insecticide ◽  
Paste Electrode

The objective of the work was to investigate the possibility of using a tricresyl phosphate-based carbon paste electrode for the direct voltammetric determination of the neonicotinoid insecticide thiamethoxam. The analyte was determined by differential pulse voltammetry in Britton-Robinson buffer pH 7.0 in the concentration range of 3.72 - 41.5 ?g mL-1. The reproducibility of the analytical signal at the 7.29 ?g mL-1 level was characterized by a relative standard deviation of 1.3 %. The applicability of the developed method was evaluated by determining thiamethoxam in a river water sample and a commercial formulation Actara 25 WG.

scholarly journals Online Coupling of Lab-on-Valve Format to Amperometry Based on Polyvinylpyrrolidone-Doped Carbon Paste Electrode and Its Application to the Analysis of Morin

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Yang Wang ◽  
Guojun Yao ◽  
Jie Tang ◽  
Chun Yang ◽  
Qin Xu ◽  
...  
Keyword(s):  
Carbon Paste Electrode ◽  
Supporting Electrolyte ◽  
Phosphate Buffer Solution ◽  
Current Response ◽  
Oxidation Peak ◽  
Carbon Paste ◽  
Buffer Solution ◽  
Electrochemical Behaviors ◽  
Paste Electrode

The potential capabilities and analytical performance of lab-on-valve (LOV) manifold as a front end to amperometry have been explored for the on-line determination of morin. Meanwhile, the electrochemical behaviors of morin were investigated based on polyvinylpyrrolidone- (PVP-) doped carbon paste electrode (CPE), which found that PVP can significantly improve its oxidation peak current. The excellent amperometric current response was achieved when the potential difference (ΔE) of 0.6 V was implemented in pH 6.5 phosphate buffer solution (PBS) that served as the supporting electrolyte. A well-defined oxidation peak has been obtained in studies using PVP as a modifier of CPE based on the oxidation of morin. The present work introduces the LOV technique as a useful tool for amperometric measurement, documents advantages of using programmable flow, and outlines means for miniaturization of assays on the basis of PVP modified CPE. The proposed method was applied successfully to the determination of morin in real samples, and the spiked recoveries were satisfactory.

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