scholarly journals Comparative efficacy of protein creatinine ratio and calcium creatinine ratio in determining organ dysfunction in ante-natal patients with pre-eclampsia

2021 ◽  
Vol 7 (3) ◽  
pp. 28-34
Author(s):  
Dr. Shanti Sah ◽  
◽  
Dr. Shipra Gupta ◽  
Dr. Ruchica Goel ◽  
◽  
...  
Keyword(s):  
Renal Function ◽  
Liver Function ◽  
Liver Function Test ◽  
Biochemical Parameters ◽  
P Value ◽  
Pregnancy Induced Hypertension ◽  
Creatinine Ratio ◽  
Renal Function Test ◽  
Induced Hypertension ◽  
Function Test

Aim: To evaluate the biochemical parameters in determining the severity of pre-eclampsia andcompare the efficacy between protein creatinine ratio and calcium creatinine ratio in determiningorgan dysfunction in ante-natal women with pregnancy-induced hypertension. Material andMethods: 150 cases of pregnancy-induced hypertension admitted in the labour room were studiedin the Department of Obstetrics and Gynaecology, SRMSIMS and were divided into two groups mildand severe pre-eclampsia depending on blood pressure, clinical and biochemical parameters. Variousparameters for renal function and liver function were evaluated along with fundoscopy. Results: Onthe evaluation of various parameters of renal function test and liver function test, a statisticallysignificant p-value was observed with increase in grade of pre-eclampsia. When abnormal organfunctions were compared, it was observed that PCR ≥ 0.3 is associated with 85%, 75.6% and81.25% cases of abnormal fundoscopy, deranged renal function test and deranged liver function testcompared to CCR ≤ 0.04 which was associated with 77%, 78.6% and 65% cases of abnormalfundoscopy, deranged renal function test and deranged liver function test respectively. Conclusion:The degree of derangement among biochemical parameters increases as the disease progresses.Early determination by a single test helps to predict organ involvement and correlates with diseaseseverity.

scholarly journals Comparative study of postoperative hepatic and renal function changes in laparoscopic and open cholecystectomy

2019 ◽  
Vol 6 (4) ◽  
pp. 1194
Author(s):  
Fazle Rab Malik ◽  
Ankur Dutt Tripathi ◽  
Santosh Kumar Singh ◽  
Anish Kola ◽  
Devendra Kumar Shukla
Keyword(s):  
Blood Flow ◽  
Renal Function ◽  
Laparoscopic Cholecystectomy ◽  
Liver Function ◽  
Open Cholecystectomy ◽  
Liver Function Tests ◽  
P Value ◽  
Renal Function Test ◽  
Function Tests ◽  
Function Test

Background: It has been shown that there is a transient elevation of serum liver enzymes after laparoscopic surgeries and major causative factor seemed to be the CO2 pneumoperitoneum. In most of the cases, it does not have any clinical significance in the patient with normal preoperative liver function. However, in patients with deranged liver function, these changes can have great significance.Methods: The present study was designed to determine and compare changes in liver function tests and renal function test following laparoscopic cholecystectomy and open cholecystectomy. This study was conducted on 100 patients admitted to Swaroop Rani Nehru Hospital, Allahabad, India from August 2017 to January 2019 who were having symptomatic cholelithiasis with a history of either acute cholecystitis, biliary colic or chronic cholecystitis. All patients were investigated for complete liver function tests and renal function test including serum bilirubin, SGOT, SGPT, alkaline phosphatase, LDH, S. urea, S. creatinine, S. Na+, S. K+, S. Ca+ and urinary sodium (UNa+). The laboratory tests were carried out in the same laboratory using one type of instrument.Results: In open cholecystectomy, bilirubin decreased by 11% (p value equals 0.191) and remained decreased to the preoperative value on day 1 and day 7. While, laparoscopic cholecystectomy at 14 mmHg pressure, mean bilirubin decreases by 14% immediately postoperatively (p value equals 0.1733) and returns to normal level in 7 days. These changes are clinically insignificant and statistically insignificant.Conclusions: Enzyme elevations could mostly be attributed to the adverse effects of the pneumoperitoneum on the hepatic blood flow and renal blood flow and CO2 absorption in the blood. Though, these changes do not seem to be clinically significant, care should be taken before deciding to perform laparoscopic cholecystectomy. This study suggested that laparoscopic cholecystectomy is a safe operative procedure and have added advantages. The disturbances in the function of the kidney after laparoscopic cholecystectomy are self-limited and not associated with any morbidity in patients with a healthy kidney function.

scholarly journals Dialysis for severe hyponatraemia in preeclampsia

2010 ◽  
Vol 3 (1) ◽  
pp. 38-39 ◽  
Author(s):  
Annemarie Hennessy ◽  
Ian Hill
Keyword(s):  
Renal Failure ◽  
Renal Function ◽  
Acute Renal Failure ◽  
Liver Function ◽  
Liver Function Test ◽  
Rare Complication ◽  
Rapid Recovery ◽  
Severe Hyponatraemia ◽  
Function Test

Severe hyponatraemia is a rare complication of preeclampsia. In the case presented, the rapid recovery of liver function test abnormalities and thrombocytopenia were accompanied by acute renal failure, relative oliguria and progressive hyponatraemia contributing to confusion and ileus. Dialysis was instigated and the patient promptly recovered. Renal function recovered fully.

scholarly journals Changes in Renal Function Test Following Kidney Donation

2020 ◽  
Vol 18 (1) ◽  
pp. 3-7
Author(s):  
Mohammed Mizanur Rahman ◽  
Probir Kumar Roy ◽  
MH Rahman ◽  
Tms Hossain ◽  
Md Waliul Islam ◽  
...  
Keyword(s):  
Renal Function ◽  
Specific Gravity ◽  
Serum Creatinine ◽  
Kidney Donation ◽  
P Value ◽  
Female Ratio ◽  
Renal Function Test ◽  
Function Test ◽  
The Mean

Objectives: The aim of this study was to find out any Changes in renal function test following kidney donation. Materials and Methods: A Hospital based prospective study was conducted in the Department of Urology of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from April 2011 to September 2012. Investigations included specific gravity and urinary microalbumin, serum creatinine. According to inclusion and exclusion criteria a total of 37 donors were enrolled in this study. Subsequent follow up were taken at the end of three months, six months and nine months. Data were evaluated by Paired t-test, Significance was defined p value<0.05. Results: The age range varied from 25 to 39 years and 45.9% of patients belonged to 25- 30 years and male to female ratio was 1:2.4. The mean baseline specific gravity was 1016.97±8.03, serum creatinine 1.03±0.24. The baseline urinary micro albumin was found nil and subsequent 1st, 2nd, and 3rd follow up were also nil. The mean difference of specific gravity, urinary micro albumin, and serum creatinine (mg/dl) were almost consistent between baseline and the subsequent follow-up, no statistical significant (P>0.05) was found between baseline and the subsequent follow-up. Conclusion: Renal function test of the remaining kidney in living donors does not significantly change after donor nephrectomy. Bangladesh Journal of Urology, Vol. 18, No. 1, Jan 2015 p.3-7

scholarly journals Efficacy and safety of Prunus mume and choline in patients with abnormal level of liver function test

2020 ◽  
Vol 7 (3) ◽  
pp. 170
Author(s):  
Muhammad N. Aslam ◽  
Anwar Ali ◽  
Suresh Kumar
Keyword(s):  
Liver Function ◽  
Liver Function Test ◽  
Aspartate Aminotransferase ◽  
Alanine Transaminase ◽  
Abnormal Liver Function Test ◽  
P Value ◽  
Prunus Mume ◽  
Efficacy And Safety ◽  
Female Ratio ◽  
Function Test

<p class="abstract"><strong>Background:</strong> The objectives of the study were to determine the efficacy and safety of <em>Prunus mume</em> and choline in patients with abnormal liver function test.</p><p class="abstract"><strong>Methods:</strong> This open labelled, multi-centered observational study was done for a from May 2019 to December 2019. Patients of either gender, above 18 years of age having elevated levels of aspartate aminotransferase, alanine transaminase or gamma-glutamyltransferase were included in the study after taking informed consent. One to two tablets of revolic per day were given preferably in the morning with breakfast or as per instructions of the physician. Patient follow-ups were done at 2<sup>nd</sup> and 4<sup>th</sup> week after treatment. SPSS version 20.0 was used for analysis. Frequency and percentages and for quantitative data, mean, standard deviation, median and interquartile range were recorded. Wilcoxon signed ranks test was applied with p value of &lt;0.05 as significant level.</p><p class="abstract"><strong>Results:</strong> Among 247 patients, male to female ratio was 2:1 with overall mean age of 42.8±12.6 years. Total bilirubin decreased from baseline to week-4 in treatment with <em>Prunus mume</em> extract and choline (p=0.04). Median and IQR of alanine transaminase levels also reduced substantially from 99 (52) to 42 (36.5) I/U. Aspartate aminotransferase levels significantly decreased from 78.5 (57) to 40 (29) I/U. Overall at the end of treatment on week-4, 26 (10.5%) patients experienced gastrointestinal distress, 25 (10.1%) anorexia, 14 (5.7%) excessive salivation and 29 (11.7%) patients experienced excessive sweating.</p><p class="abstract"><strong>Conclusions: </strong>This study reported significant improvement in alanine transaminase and aspartate aminotransferase levels after treatment with <em>Prunus mume</em> extract and choline (revolic). It is safe and effective to use them for deranged liver functions tests.</p>

scholarly journals A Descriptive Study of Colorectal Cancer in Hiwa Cancer Hospital, Sulaymaniyah, Iraq

2017 ◽  
Vol 5 (3) ◽  
pp. 244
Author(s):  
Kochar I Mahmood ◽  
Kadhim F. Namiq ◽  
Chovin A. Muhamad ◽  
Begard O. Muhamad ◽  
Kurdistan M. Majed ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Renal Function ◽  
Liver Function ◽  
Blood Cells ◽  
Biochemical Parameters ◽  
Impaired Renal Function ◽  
White Blood Cells ◽  
P Value ◽  
Demographic Parameters ◽  
Cancer Hospital

Colorectal cancer is the third most common cancer and the fourth leading cause of death from cancer worldwide. This study provides an overview of changes in sociod-demographic parameters in patients with colorectal cancer (henceforth CRC) disease in a local cancer hospital in Sulaymaniyah province of Kurdistan region of Iraq. The study included 113 patients admitted to Hiwa Cancer Hospital, Sulaymaniyah from January 2014 to December 2015. The data collection lasted for 3 weeks (from 19/12/2015 to 11/01/2016) and was obtained from the management department of Hiwa Cancer Hospital. Several socio-demographic parameters including age, gender, and smoking, as well as biochemical parameters such as liver function, renal function and blood glucose level were studied and statistically analyzed. Results have shown that the majority of CRC patients were neither current smoker nor x-smoker (P-value < 0.05). Males suffered from CRC at an earlier age compared to females (P-value < 0.05). Regarding the biochemical tests, there was no significant correlation between CRC and impaired liver function during the diagnosis process and most of the study patients had a normal liver function test on presentation. In contrast, the correlation between CRC and impaired renal function on presentation was statistically siginificant (P-value < 0.05). No significant difference was noted in the means of hematological and biochemical parameters between males and females, except for white blood cells and serum Aspartate Aminotransferase. White blood cells and total serum bilirubin showed significant differences (P-value < 0.05) between smoker and nonsmoker sub-populations. It was concluded that CRC is one of the common cancers in Sulaymaniyah province. Males develop it at an earlier age compared to females, and the impaired renal function is a significant finding on presentation.

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