Method of DNA-comet assay in the diagnosis of liver fibrosis in patients with chronic viral hepatitis C
2015 ◽
Vol 20
(2)
◽
pp. 29-33
Keyword(s):
In the study there were included 100 patients, which were selected in 5 group in dependence on the degree of liver fibrosis: I - F0, II - F1, III - F2, IV- F3, V - F4. Sixth (control) group was consisted of 43 healthy volunteers. The performed research has shown the relationship between the stage of fibrosis and the degree of DNA degradation in peripheral blood lymphocytes. The biggest level of DNA destruction in peripheral blood lymphocytes was established in group V patients with chronic viral hepatitis C. This allowed to consider method of DNA-comet assay as promising auxiliary method in the assessment of the formation of liver fibrosis.
2019 ◽
Vol 44
(12)
◽
pp. 4011-4021
◽
Keyword(s):
2017 ◽
Vol 48
(2)
◽
pp. 329-337
◽
2017 ◽
Vol 48
(1)
◽
pp. 31-42
◽
2021 ◽