E. Ulrich. On the issue of prevention and treatment of postoperative pneumonia with quinine-calcium. (Zbl. F. Ghir., 1936, 38, 2244-2247)

1937 ◽  
Vol 33 (7) ◽  
pp. 939-939
Author(s):  
B. Ivanov
Keyword(s):  
Postoperative Complications ◽  
Pulmonary Complications ◽  
Gluteal Region ◽  
Postoperative Pneumonia ◽  
Postoperative Pulmonary Complications ◽  
Prophylactic Administration ◽  
Prevention And Treatment

Based on his observations, a. indicates that as a result of the prophylactic administration of quinine-calcium on the day of surgery and on the next two days, the frequency of postoperative pulmonary complications is reduced by about three times, and the developing complications are relatively easy (in 2/3 cases, it was only about simple bronchitis); in cases where the prophylactic administration of quinine-calcium was not produced, the vast majority of postoperative complications were pneumonia and bronchopneumonia. A. also reports on the good results of the use of quinine-calcium as a remedy for bronchitis, pneumonia and bronchopneumonia. Using Sandoz quinine calcium, as well. for prophylactic purposes, it injects it into the muscles of the gluteal region in an amount of 10 cm3 on the day of surgery, 2 times 10 cm3 the next day and another 10 cm3 on the second day after surgery.

scholarly journals Application of Positive End-Expiratory Pressure (PEEP) in Patients During Prolonged Gynecological Surgery

2019 ◽  
Vol 46 (1) ◽  
pp. 28-33
Author(s):  
V. Koritarova ◽  
S. Georgiev
Keyword(s):  
Postoperative Complications ◽  
Pulmonary Complications ◽  
Protective Ventilation ◽  
Control Group ◽  
Gynecological Surgery ◽  
Ventilation Strategy ◽  
Postoperative Pulmonary Complications ◽  
Protective Ventilation Strategy ◽  
Group A ◽  
Group B

Abstract Introduction: A lot of clinical studies have shown that during prolonged surgery protective ventilation strategy, including low tidal volume, PEEP and recruitment maneuvers (RM) can reduce the rate of postoperative pulmonary complications, which are the second most common cause for postoperative mortality. Therefore, it is important to investigate clinical methods for preventing them. The strategy of protective ventilation is easy and safe for the patients and inexpensive for application during prolonged surgery. Aims: The objective of this trial was to study whether application of PEEP in patients during prolonged gynecological surgery could decrease the postoperative complications. Material and Methods: We compared the rates of postoperative complications in patients after prolonged open gynecological surgery, who were divided into 2 groups – group A, which was the control group on non-protective ventilation (35 patients) and group B on protective ventilation (35 patients). The patients in the control group were ventilated with tidal volume (VT) of 8-10 ml/kg without PEEP and RM; the patients in group B were ventilated with VT = 6-8 ml/kg according to their Predicted Body Weight, with a PEEP of 6 cm H2O and RM, which consisted of applying continuous positive airway pressure of 30 cm H2O for 30 seconds. RM was performed after intubation, after every disconnection from ventilator and before extubation. The study was successfully performed without a need for a change in the type of ventilation strategy because of hypoxia or hemodynamic instability. Statistical nonparametric test (e.g. chi-square) was applied. Results: Total rate of all postoperative complications observed in both groups was 27,1%. We found a significant relationship between application of PEEP and lower rates of postoperative pulmonary complications in group A (39,4%) compared to group B (12,1%), lower rate of respiratory failure (33,3% in group A vs. 9,1% in group B -) and atelectasis (21,2% in group A vs. 0% in group B). Conclusion: The protective ventilation strategy (low VT, PEEP and RM) in patients during prolonged gynecological surgery can reduce the rate of postoperative pulmonary complications such as respiratory failure and atelectasis.

scholarly journals Prospective comparison of the effects of intraoperative goal-directed fluid therapy and restrictive fluid therapy on complications in thoracoscopic lobectomy

2021 ◽  
Vol 49 (12) ◽  
pp. 030006052110627
Author(s):  
Min Li ◽  
Mingqing Peng
Keyword(s):  
Postoperative Complications ◽  
Fluid Therapy ◽  
Therapy Group ◽  
Pulmonary Complications ◽  
Fluid Volume ◽  
Postoperative Pulmonary Complications ◽  
Clinical Trial Registry ◽  
Thoracoscopic Lobectomy ◽  
Prospective Comparison ◽  
Goal Directed Fluid Therapy

Objective Restrictive fluid therapy is recommended in thoracoscopic lobectomy to reduce postoperative pulmonary complications, but it may contribute to hypovolemia. Goal-directed fluid therapy (GDFT) regulates fluid infusion to an amount required to avoid dehydration. We compared the effects of GDFT versus restrictive fluid therapy on postoperative complications after thoracoscopic lobectomy. Methods In total, 124 patients who underwent thoracoscopic lobectomy were randomized into the GDFT group (group G, n = 62) or restrictive fluid therapy group (group R, n = 62). The fluid volume and postoperative complications within 30 days of surgery were recorded. Results The total fluid volume in groups G and R was 1332 ± 364 and 1178 ± 278 mL, respectively. Group R received a smaller colloid fluid volume (523 ± 120 vs. 686 ± 180 mL), had a smaller urine output (448 ± 98 vs. 491 ± 101 mL), and received more norepinephrine (120 ± 66 vs. 4 ± 18 µg) than group G. However, there were no significant differences in postoperative pulmonary complications, acute kidney injury, length of hospital stay, or in-hospital mortality between the two groups. Conclusion Restrictive fluid therapy performs similarly to GDFT in thoracoscopic lobectomy but is a simpler fluid strategy than GDFT. Trial registration: This study has been registered at the Chinese Clinical Trial Registry (ChiCTR2100051339) ( http://www.chictr.org.cn/index.aspx ).

scholarly journals Spirometric lung age for predicting the risk of pulmonary complications after thoracic surgeries

2021 ◽  
Vol 25 (4) ◽  
pp. 563-566
Author(s):  
O. Yu. Usenko ◽  
A. V. Sydiuk ◽  
O. E. Sydiuk ◽  
A. S. Klimas ◽  
G. Yu. Savenko ◽  
...  
Keyword(s):  
Strong Association ◽  
Pulmonary Complications ◽  
Postoperative Pneumonia ◽  
Thoracic Cavity ◽  
Postoperative Pulmonary Complications ◽  
Optimal Point ◽  
Term Survival ◽  
Statistical Software ◽  
Respiratory Dysfunction ◽  
Lung Age

Annotation. Surgical interventions for diseases of the thoracic cavity are one of the most invasive surgical procedures, which are often accompanied by postoperative complications, which increase mortality, prolong hospital stays, require additional costs and correlate with poor long-term survival. However, respiratory complications remain the most common of non-surgical complications and their frequency varies from 13 to 38%. So far, several studies have shown that respiratory dysfunction is an independent risk factor for postoperative pneumonia. The aim – investigate whether it is possible to use spirometric lung age to predict the occurrence of postoperative pneumonia after thoracic surgeries. The study was performed on 192 patients with diseases of the thoracic cavity (esophagus, lungs, mediastinum), underwent surgery in the thoracoabdominal department of the Shalimov’s National Institute of Surgery and Transplantation. Statistical software EZR v.1.54 was used for statistical calculations (graphical user interface for statistical software R version 4.0.3, R Foundation for Statistical Computing, Vienna, Austria). We found a very strong association between the risk of developing pulmonary complications and the age of the lungs, AUC=0.97 (95% confidence interval from 0.94 to 0.99). When choosing the optimal point for predicting the risk of pulmonary complications obtained: Lung age critical = 99.6 years. Thus, at Lung age >99.6 years, the development of postoperative pulmonary complications is predicted. At Lung age <99.6 years, the absence of postoperative pulmonary complications is predicted. When choosing this decision point, the sensitivity is 93.5% (82.1-98.6%), specificity – 95.9% (91.3-98.5%). Therefore, spirometric age of the lungs was associated with the incidence of postoperative pulmonary complications in patients undergoing surgery for thoracic disease. This parameter deserves attention as a predictor of the probability of developing postoperative pneumonia after thoracic surgeries and can help in assessing the state of respiratory function of patients.

scholarly journals The Clinical Value of Pulmonary Rehabilitation in Reducing Postoperative Complications and Mortality of Lung Cancer Resection: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Xiaowei Mao ◽  
Yiqian Ni ◽  
Yanjie Niu ◽  
Liyan Jiang
Keyword(s):  
Postoperative Complications ◽  
Pulmonary Rehabilitation ◽  
Pulmonary Resection ◽  
Meta Analysis ◽  
Pulmonary Complications ◽  
Random Regression ◽  
Postoperative Pulmonary Complications ◽  
Clinical Value ◽  
Systemic Analysis ◽  
Complications And Mortality

Background: Pulmonary rehabilitation is one meaningful way of improving exercise tolerance and pulmonary function. Thus, it may reduce the postoperative complications and mortality of pulmonary resection. Hence, we refreshed the data and conducted this systemic analysis.Method: We searched Pubmed, Web of Science, and EMBASE using “lung OR pulmonary” AND “operation OR resection OR surgery” AND “rehabilitation or exercise.” The cut-off date was September 30, 2020. The publications were filtrated, and data were extracted from all selected studies by two reviewers. Review Manger 5.1 and the fixed or random regression model were used for calculating the pooled odds ratio (OR).Result: Finally, 13 publications were enrolled in this study. Among them, five publications reported mortality, nine reported postoperative complications, and seven reported postoperative pulmonary complications. The pooled OR of mortality was 1.32 [95% confidence interval (CI): 0.54–3.23] for the pulmonary rehabilitation group, the pooled OR of postoperative complications was 0.62 (95% CI: 0.49–0.79) for the pulmonary rehabilitation group, and the pooled OR of postoperative pulmonary complications was 0.39 (95% CI: 0.27–0.56) for the pulmonary rehabilitation group. Subgroup analysis revealed the perioperative pulmonary rehabilitation was the most important part.Conclusion: Pulmonary rehabilitation may not affect the mortality of pulmonary resection patients, however, it could decrease the number of postoperative complications, especially pulmonary complications. Perioperative pulmonary rehabilitation was the most important part of the program.

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