scholarly journals Viewing vertebral arteries by duplex scan: what to expect

1996 ◽  
Vol XXVIII (1-2) ◽  
pp. 16-19
Author(s):  
М. Salaschek
Keyword(s):  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Carotid Arteries ◽  
Pathological Findings ◽  
Peripheral Vascular ◽  
Duplex Scan ◽  
Vertebral Arteries ◽  
The Mean ◽  
The Right ◽  
Clear Predominance

In vertebral arteries (v.a) most stenoses occur at their origins. Ultrasound studies with a 7,5 MHz sector duplex-probe are able to reveal the origins in 63 68% of the right, in 4362% of the left vertebral arteries (men omen), whereas the prevertebral and the intertrans versal parts C5/6C3/4 are visualized in 7090%. The mean cumulative lumen of both v.a. increases by age from 6,0 mm (age30) to 7,9 mm (age80) with a clear predominance of the left v.a. in 33%, of the right v.a. in 17%. Hypoplasia of one or both v.a. is present in 5,2%. In a sample of 1131 patients pathological findings occuredin 11% of the vertebral arteries (stenoses or occlusions, steal phenomena) and in 16% of the carotid arteries (stenoses 50% occlusions). In 42% of the cases with infarctions in the vertebro-basilar-supplied territories pathological duplex-findings were present, similary in 20% of infarctions in the carotid supplied territories, and in 15% of vertigo, but also in 62% of patients with peripheral vascular disease without, neurological signs or symptoms versus only in 3% of control-patients of similar age with out neurological or peripheral vascular disease.

scholarly journals Potentiation of Heparin by Dextran and its Clinical Implication

1977 ◽  
Author(s):  
M. Atik
Keyword(s):  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Clinical Implication ◽  
Bleeding Time ◽  
Platelet Adhesiveness ◽  
Peripheral Vascular ◽  
Clotting Time ◽  
Potentiation Effect ◽  
Antithrombotic Effects ◽  
The Mean

The different mechanisms underlying the antithrombotic effects of heparin and dextran are known. To document the clinically suspected potentiation effect when the two agents are used together, the following study was undertaken:In 9 patients with peripheral vascular disease, the Ivy bleeding time, the Lee-White clotting time and the platelet adhesiveness by Hellem method, were determined at control periods and at 1 and 3 hours following infusion of various doses of heparin alone. These were repeated on separate days after infusion of 500 ml of dextran in combination with same doses of heparin.While dextran alone had no effect on the clotting time, it produced a marked and statistically significant potentiation of heparin effect (P<0.01). The mean clotting time one hour after infusion of 10,000 u of heparin was increased from 36 min. with dextran to 69 min. with dextran. This effect persisted at 3 hours. The mean clotting time after 5,000 u of heparin with dextran was almost the same as after 10,000 u of heparin with dextran. The potentiation was slight at 2.500 u of heparin. Heparin did not affect platelet adhesiveness. Dextran suppressed it when it was abnormally high, but did not reduce it below the normal value of 41 ± 9%. There was no demonstrable changes in the bleeding time by either dextran or heparin at the dosage given.Our clinical experience and reports of other investigators suggest the desirability of the use of the two drugs in certain circumstances. To be effective and yet safe, it is recommended that whenever heparin is used in patients receiving dextran the dosage should be reduced to a half or a third of the usual.

scholarly journals Epidemiology of Peripheral Vascular Disease in the Long Life Family Study (LLFS)

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 55-55
Author(s):  
Allison Kuipers ◽  
Ryan Cvejkus ◽  
Emma Barinas-Mitchell ◽  
Mary Feitosa ◽  
Joanne Murabito ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Ankle Brachial Index ◽  
Posterior Tibial Artery ◽  
Epidemiologic Studies ◽  
Peripheral Vascular ◽  
Current Smoking ◽  
The Mean ◽  
Artery Disease

Abstract Atherosclerotic occlusion of peripheral arteries is a major contributor to morbidity and mortality in older adults. Our aim was to describe the epidemiology of peripheral artery disease (PAD) and other peripheral vascular disease (OPD) in the LLFS. 3248 individuals from 509 families (1182 probands, mean age 89; 2066 offspring, mean age 60) had doppler ankle-brachial index (ABI) assessment. Measures were performed twice for each posterior tibial artery and minimum of the mean ABI was used. PAD was defined as any ABI&lt;0.9. OPD was defined as any ABI &gt;1.4 or ≥1 non-compressible artery. Stepwise linear or logistic regression determined significant independent clinical and demographic predictors (P&lt;0.05) after adjustment for age, sex, study center, and familial relatedness. Overall, ABI had a median of 1.2 with 7.4% PAD (18.1% probands, 1.2% offspring; P&lt;0.001). OPD prevalence was 10.6% and was more common than PAD in offspring (8.1%). Age-adjusted OPD was higher in men (13.3%) than women (8.3%, P&lt;0.001), while age-adjusted PAD did not did not differ by sex (P=0.45). Predictors of PAD included greater age and systolic blood pressure, lower diastolic blood pressure, prevalent kidney disease, antihypertensive use, and current smoking. Predictors of OPD included greater age, male sex, and current smoking. In these exceptionally long-lived families, PAD was low compared to other epidemiologic studies. However, OPD including non-compressible arteries, a marker of arterial stiffness, was more prevalent than PAD. These findings in long-lived families highlight a need for more epidemiologic research in other peripheral vascular disease in adults from the general population.

Safety of Limited Supplemental Iodinated Contrast Administration in Azotemic Patients Undergoing CO2 Angiography

2003 ◽  
Vol 10 (2) ◽  
pp. 312-316 ◽  
Author(s):  
Kyran Dowling ◽  
Herman Kan ◽  
Gary Siskin ◽  
Brian Stainken ◽  
Jiyong Ahn ◽  
...  
Keyword(s):  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Peripheral Vascular ◽  
Contrast Administration ◽  
Relative Safety ◽  
Iodinated Contrast ◽  
Diagnostic Angiography ◽  
The Mean ◽  
Pre Treatment ◽  
Contrast Group

Purpose: To determine if limited doses of iodinated contrast significantly worsen the underlying renal insufficiency that had warranted the use of CO2 for diagnostic angiography. Methods: The records of 122 consecutive patients who had undergone CO2 angiography for peripheral vascular disease at our institution over a 5-year period were reviewed. The volume and type of iodinated contrast and the volume of CO2 administered were recorded. Serum creatinine measurements obtained before angiography and from 2 to 3 days after angiography were recorded. Results: One hundred patients had pre-angiography and post-angiography creatinine levels available for analysis (51 CO2 only, 49 CO2 with iodinated contrast). The average pre-treatment creatinine level was 2.8±1.5 mg/dL (range 1.8–6.6) for the CO2 only group and 3.0±1.4 mg/dL (range 1.8–8.2) for the CO2 plus iodinated contrast group (p=0.46). After angiography, the mean change in creatinine was +0.17±0.87 mg/dL for the CO2 only group and +0.03±0.98 mg/dL in the CO2 plus contrast group (p=0.27). Complications included 1 patient with a failing renal transplant who received iodinated contrast and ultimately required return to hemodialysis. A second patient had a transient 1-mg/dL rise of creatinine but did not require dialysis. Conclusions: This study supports the relative safety of CO2 angiography with the limited used of iodinated contrast supplementation for diagnostic studies or interventions in azotemic patients with peripheral vascular disease.

Tests for Platelet Changes, Acute Phase Reactants and Serum Lipids in Diabetes mellitus and Peripheral Vascular Disease

1982 ◽  
Vol 48 (03) ◽  
pp. 289-293 ◽  
Author(s):  
B A van Oost ◽  
B F E Veldhuyzen ◽  
H C van Houwelingen ◽  
A P M Timmermans ◽  
J J Sixma
Keyword(s):  
Diabetes Mellitus ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Acute Phase ◽  
Serum Lipids ◽  
Diabetic Patients ◽  
Peripheral Vascular ◽  
Acute Phase Reactants ◽  
Control Subjects ◽  
And Control

SummaryPlatelets tests, acute phase reactants and serum lipids were measured in patients with diabetes mellitus and patients with peripheral vascular disease. Patients frequently had abnormal platelet tests and significantly increased acute phase reactants and serum lipids, compared to young healthy control subjects. These differences were compared with multidiscriminant analysis. Patients could be separated in part from the control subjects with variables derived from the measurement of acute phase proteins and serum lipids. Platelet test results improved the separation between diabetics and control subjects, but not between patients with peripheral vascular disease and control subjects. Diabetic patients with severe retinopathy frequently had evidence of platelet activation. They also had increased acute phase reactants and serum lipids compared to diabetics with absent or nonproliferative retinopathy. In patients with peripheral vascular disease, only the fibrinogen concentration was related to the degree of vessel damage by arteriography.

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