scholarly journals Comparison of the effects of hyperbaric and normobaric oxygen treatments on the repolarisation parameters of electrocardiography in children with carbon monoxide poisoning

2021 ◽  
Vol 46 (4) ◽  
pp. 1606-1613
Author(s):  
Zafer BAĞCI ◽  
Abdullah ARSLAN ◽  
Derya ARSLAN ◽  
Ayşenur KOLSUZ
Keyword(s):  
Carbon Monoxide ◽  
Carbon Monoxide Poisoning ◽  
Normobaric Oxygen

scholarly journals An Analysis of Patients With Carbon Monoxide Poisoning Transported by a Physician-Staffed Helicopter

2019 ◽  
pp. 43-47
Author(s):  
iroki Nagasawa ◽  
Youichi Yanagawa
Keyword(s):  
Carbon Monoxide ◽  
Study Design ◽  
Carbon Monoxide Poisoning ◽  
Male Gender ◽  
Co Poisoning ◽  
Middle Aged ◽  
Normobaric Oxygen ◽  
Base Hospital ◽  
Oxygen Treatment ◽  
Before And After

OBJECTIVE: We retrospectively investigated a series of patients with carbon monoxide (CO) poisoning transported by a physician-staffed helicopter (DH) to seek evidence supporting the daily management of patients with CO poisoning. STUDY DESIGN: Subjects were divided into two groups: the carboxyhemoglobin saturation (SpCO) (+) group, which included patients who had a pulse CO-oximeter attached during transportation; and the SpCO (-) group, which included all other patients. We compared the level of SpCO before and after transportation when the level was noted. RESULTS: The subjects were predominantly middle-aged and male. Seventeen subjects (53.1%) received a diagnosis of CO poisoning based on the situation in which the subjects were found, without the carboxyhemoglobin level being measured. No subjects show deterioration of their condition after transportation, and none ultimately died. The frequency of male gender, normobaric oxygen treatment and return to the base hospital in the SpCO (+) group was significantly greater than in the SpCO (-) group. The SpCO levels after transportation were significantly lower than they had been before transportation. CONCLUSION: This is the first study to show the results of the analysis of patients with CO poisoning transported by the DH. All patients with CO poisoning were safely transported.

scholarly journals Extracorporeal Hyperoxygenation Therapy (EHT) for Carbon Monoxide Poisoning: In-Vitro Proof of Principle

Membranes ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 56
Author(s):  
Niklas B. Steuer ◽  
Peter C. Schlanstein ◽  
Anke Hannig ◽  
Stephan Sibirtsev ◽  
Andreas Jupke ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Carbon Monoxide Poisoning ◽  
Hollow Fibre ◽  
Co Poisoning ◽  
Normobaric Oxygen ◽  
Elevated Pressures ◽  
Bubble Oxygenator ◽  
Novel Method ◽  
The Difference

Carbon monoxide (CO) poisoning is the leading cause of poisoning-related deaths globally. The currently available therapy options are normobaric oxygen (NBO) and hyperbaric oxygen (HBO). While NBO lacks in efficacy, HBO is not available in all areas and countries. We present a novel method, extracorporeal hyperoxygenation therapy (EHT), for the treatment of CO poisoning that eliminates the CO by treating blood extracorporeally at elevated oxygen partial pressure. In this study, we proof the principle of the method in vitro using procine blood: Firstly, we investigated the difference in the CO elimination of a hollow fibre membrane oxygenator and a specifically designed batch oxygenator based on the bubble oxygenator principle at elevated pressures (1, 3 bar). Secondly, the batch oxygenator was redesigned and tested for a broader range of pressures (1, 3, 5, 7 bar) and temperatures (23, 30, 37 °C). So far, the shortest measured carboxyhemoglobin half-life in the blood was 21.32 min. In conclusion, EHT has the potential to provide an easily available and effective method for the treatment of CO poisoning.

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